US Patent:
20100291152, Nov 18, 2010
Inventors:
Clifford Shone - Wiltshire, GB
Xiaomi Tong - Leesburg VA, US
Joanna Clancy - Wilmington NC, US
Mili Gu - Gaithersburg MD, US
International Classification:
A61K 39/07
A61K 39/08
A61P 31/04
C07K 1/113
Abstract:
The invention provides processes for improving the ability of a peptide to stimulate an immune response, comprising exposing the peptide to a chemical modifying agent. It further provides compositions comprising an antigenic peptide, wherein the peptide has been treated with a chemical modifying agent to improve its ability to stimulate an immune response. It also provides methods of stimulating an immune response in a mammal, comprising administering to the mammal an effective amount of a vaccine.
