Inventors:
Joseph C. McAuliffe - Sunnyvale CA, US
Wyatt Charles Smith - Tiburon CA, US
Michael S. Starch - Midland MI, US
Assignee:
Dow Corning Corporation - Midland MI
International Classification:
A61K 31/7012
A61K 31/7024
A61K 31/695
A61K 31/25
A61K 31/215
A61K 31/22
A61K 31/23
C07H 13/02
C07H 13/04
C07F 7/04
C07F 7/08
C07F 7/18
US Classification:
514 54, 514 63, 514530, 514548, 514551, 514552, 514546, 536 55, 536 553, 536119, 556437, 556430, 556457, 556489, 556482
Abstract:
Novel ester derivatives of ascorbic acid and 2-keto-acid saccharides are provided wherein the ester is introduced by ester bond formation between at least one hydroxy-functionality on the ascorbic acid or 2-keto-acid saccharide and a carboxy-functional organosiloxane, or between a 2-keto-gulonic acid and a hydroxy-functional organosiloxane, as well as methods for their synthesis. Treatment, cosmetic, and personal care formulations comprising the novel esters are also provided, including controlled release forms thereof.