Inventors:
Haim H. Bau - Swarthmore PA, US
Michael G. Schrlau - Drexel Hill PA, US
Rui Zhang - Drexel Hill PA, US
Assignee:
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA - Philadelphia PA
International Classification:
C12M 1/34
B44C 1/22
G01N 27/26
B05D 5/12
US Classification:
435 29, 427 58, 216 13, 427122, 4271261, 427124, 427123, 4352871
Abstract:
Provided are probes featuring multiple electrodes, which probes have diameters in the nanometer range and may be inserted into cells or other subjects so as to monitor an electrical characteristic of the subject. The probes may also include a conductive coating on at least one probe element to improve the probes' performance. The probes may also be used to inject a fluid or other agent into the subject and simultaneously monitor changes in the subject's electrical characteristics in response to the injection. Related methods of fabricating and of using the inventive probes are also provided.