Mateusz L Hupert

20090074637, Mar 19, 2009

Jun 30, 2008

12/164356

Michael C. Murphy - Baton Rouge LA, US
Dimitris E. Nikitopoulos - Baton Rouge LA, US
Steven A. Soper - Baton Rouge LA, US
Daniel S.-W. Park - Baton Rouge LA, US
Mateusz L. Hupert - Baton Rouge LA, US

B01J 19/00

422206, 422240

Passively aligned modular microfluidic devices, and a method for fabricating such passively aligned polymeric modular microfluidic devices have been reported. The modular units fabricated are plurality of integrated microdevices. Also reported are microfluidic devices wherein isolated temperature zones exist so that the temperature within each zone may be distinctly and accurately controlled, and a method for fabricating such microfluidic devices wherein there are isolated temperature zones so that the temperature within each zone may be distinctly and accurately controlled. Such devices allow one to define constant temperature zones along a microfluidic channel where different reactions or stages of reactions occur.

20190346422, Nov 14, 2019

Jul 17, 2019

16/513947

- Chapel Hill NC, US
- Ithaca NY, US
- Baton Rouge LA, US
Michael Murphy - Baton Rouge LA, US
Collin J. McKinney - Durham NC, US
John William Efcavitch - San Carlos CA, US
Mateusz Hupert - Chapel Hill NC, US

G01N 33/487
C12Q 1/6869
C12M 1/40
B01L 3/00
C12M 3/06
C12Q 1/6806

The present invention is directed to a device that comprises a biomolecular processor and one or more nanotubes. Each biomolecular processor comprises a bioreactor chamber defined by a solid substrate, a plurality of spaced support structures within said bioreactor chamber and attached to the solid substrate, and one or more capture molecules immobilized to some or all of said plurality of spaced support structures, said one or more capture molecules suitable to bind to a portion of a target nucleic acid molecule in a sample. The device also comprises one or more nanotubes defined by the solid substrate and fluidically coupled to the bioreactor chamber. Each of the one or more nanotubes has a passage extending between an input end proximate to the bioreactor chamber and an output end distal to the bioreactor chamber, and comprises one or more nanopores within the passage with each nanopore having a reduced diameter relative to the passage. Also disclosed are systems including one or more units for upstream sample preparation. Methods of using these devices or systems are also disclosed.

20180074039, Mar 15, 2018

Mar 23, 2016

15/560028

- Chapel Hill NC, US
- Ithaca NY, US
- Baton Rouge LA, US
Michael Murphy - Baton Rouge LA, US
Collin J. Mckinney - Durham NC, US
John William Efcavitch - San Carlos CA, US
Mateusz Hupert - Chapel Hill NC, US

G01N 33/487
C12Q 1/68
B01L 3/00

The present invention is directed to a device that comprises a biomolecular processor and one or more nanotubes. Each biomolecular processor comprises a bioreactor chamber defined by a solid substrate, a plurality of spaced support structures within said bioreactor chamber and attached to the solid substrate, and one or more capture molecules immobilized to some or all of said plurality of spaced support structures, said one or more capture molecules suitable to bind to a portion of a target nucleic acid molecule in a sample. The device also comprises one or more nanotubes defined by the solid substrate and fluidically coupled to the bioreactor chamber.

20160359179, Dec 8, 2016

Feb 24, 2015

15/109167

- Chapel Hill NC, US
Mateusz L. Hupert - Chapel Hill NC, US
Steven Soper - Baton Rouge LA, US

H01M 8/04089
F28F 13/06
F15D 1/00

A fluid array, comprises: (a) a fluid input header, (b) a fluid output header, and (c) a plurality of (preferably at least 26) parallel fluid channels, each of said fluid channels connected to both said fluid input header and said fluid output header in a Z-array configuration. Methods of using the same and fuel cells comprising such arrays are also described, along with methods of optimizing flow therein.

20150099642, Apr 9, 2015

Jul 23, 2012

14/234011

Francis A. Barany - New York NY, US
Steven A. Soper - Baton Rouge LA, US
George Grills - Trumansburg NY, US
Yu-wei Cheng - Chicago IL, US
Jianmin Huang - Elmhurst NY, US
Malgorzata A. Witek - Chapel Hill NC, US
Daniel San-won Park - Baton Rouge LA, US
Michael C. Murphy - Baton Rouge LA, US
Robin Lindsey McCarley - Prairieville LA, US
Mateusz L. Hupert - Chapel Hill NC, US

Board of Supervisors of Louisiana State University and Agricultural and Mechanical College - Batou Rouge LA
CORNELL UNIVERSITY - Ithaca NY

C12Q 1/68

506 2, 506 38, 435 912

The present invention is directed to methods for capturing, amplifying and identifying one or more of a plurality of target nucleotide sequences in a sample. The present invention is further directed to a device comprising a solid support having a plurality of wells or pillars and a plurality of oligonucleotides attached to the wells or pillars. Other aspects of the invention are directed to methods of making such devices.