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Marie Piechocki Phones & Addresses

  • 16260 Pine Ridge Dr, Fraser, MI 48026 (586) 415-1842
  • Saint Clair Shores, MI
  • Toledo, OH
  • Hamtramck, MI
  • 16260 Pine Ridge Dr N #22, Fraser, MI 48026 (586) 415-1842

Work

Position: Homemaker

Publications

Us Patents

Vaccines Targeting Cellular Death Receptors

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US Patent:
20120189572, Jul 26, 2012
Filed:
Nov 6, 2009
Appl. No.:
13/128046
Inventors:
Wei-Zen Wei - Grosse Pointe Farms MI, US
Gen Sheng Wu - Troy MI, US
Marie P. Piechocki - Fraser MI, US
Richard F. Jones - Fayetteville NY, US
International Classification:
A61K 39/00
A61P 35/00
G01N 33/53
A61P 37/04
A61K 39/395
G01N 21/64
A61K 39/39
US Classification:
424 851, 4241841, 436513, 4241921, 4242391, 4242041, 4242321, 4242331, 4242071, 4242571, 4242581, 4241721, 435 792
Abstract:
The invention provides therapeutics and methods to induce a mammalian host, including a human, to produce antibodies, which agonize death receptors and cause the apoptotic death of target cells within the host's body. The therapeutics are vaccine compositions, including genetic vaccines encoding death receptor antigens of the tumor necrosis factor receptor family. Also provided are means and methods for overcoming host immunological tolerance to death receptors. The vaccines are useful against cancer cells and other death receptor bearing target cells within the host, and can be used in both therapeutic and prophylactic settings. The vaccines are also useful for diagnostic testing of the immunocompetence of a host.

Vaccines Targeting Cellular Death Receptors

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US Patent:
20140205538, Jul 24, 2014
Filed:
Jan 15, 2014
Appl. No.:
14/155592
Inventors:
Wei-Zen Wei - Grosse Pointe Farms MI, US
Gen Sheng Wu - Troy MI, US
Marie P. Piechocki - Fraser MI, US
Richard F. Jones - Fayetteville NY, US
Assignee:
Wayne State University - Detroit MI
International Classification:
A61K 39/00
A61K 38/19
A61K 49/00
A61K 39/395
US Classification:
424 91, 4241841, 4242771, 4241731
Abstract:
The invention provides therapeutics and methods to induce a mammalian host, including a human, to produce antibodies, which agonize death receptors and cause the apoptotic death of target cells within the host's body. The therapeutics are vaccine compositions, including genetic vaccines encoding death receptor antigens of the tumor necrosis factor receptor family. Also provided are means and methods for overcoming host immunological tolerance to death receptors. The vaccines are useful against cancer cells and other death receptor bearing target cells within the host, and can be used in both therapeutic and prophylactic settings. The vaccines are also useful for diagnostic testing of the immunocompetence of a host.
Marie P Piechocki from Fraser, MIDeceased Get Report