Inventors:
Antonio Gualberto - East Greenwich RI, US
Maria Luisa Paccagnella - Noank CT, US
Carrie L. Melvin - Ledyard CT, US
Madeline I. Repollet - Fort Washingtion PA, US
David Chianese - Ardmore PA, US
Mark Carle Connelly - Doylestown PA, US
Leonardus Wendelinus Mathias Marie Terstappen - Huntingdon Valley PA, US
International Classification:
G01N 33/574
Abstract:
Methods for the detection, enumeration and analysis of circulating tumor cells expressing insulin-like growth factor-1 receptors (IGF-1R) are disclosed. These methods are useful for cancer screening and staging, development of treatment regimens, and for monitoring for treatment responses, cancer recurrence or the like. Test kits that facilitate the detection, enumeration and analysis of such circulating tumor cells are also provided.