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Magda M Gagliardi

from Newtown, CT
Age ~94
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Also known as:
Magda M Gagliard
Phone and address:
837 Brookside Ct, Newtown, CT 06470
Related to:
Christina M Gagliardi, 48Julie A Gagliardi, 57Lauren GagliardiLauren Gagliardi, 67Beverly Spencer, 74
Connected to:
Aislinn S Gagliardi, 43Aldo L Gagliardi, 41Alex G Gagliardi, 39Andre C Gagliardi, 34Anthony Gagliardi, 56Ben S Gagliardo, 88Beth A Gagliardi, 39Bianca Gagliardi, 59Collin J Gagliardi, 29Crystal A Gagliardi, 43

Magda Gagliardi Phones & Addresses

  • 837 Brookside Ct, Newtown, CT 06470
  • 16 Wisteria Ct, Monmouth Junction, NJ 08852 (732) 355-1766
  • Somerset, NJ

Publications

Us Patents

Hiv Integrase Inhibitors

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US Patent:
6395743, May 28, 2002
Filed:
Oct 12, 2000
Appl. No.:
09/689174
Inventors:
Brian Heimbuch - North Brunswick NJ
Sheo Singh - Edison NJ
Deborah L. Zink - Manalapan NJ
Magda Gagliardi - Monmouth Junction NJ
Olga Genilloud - Madrid, ES
Ana Teran - Madrid, ES
Assignee:
Merck Co., Inc. - Rahway NJ
International Classification:
A61K 3144
US Classification:
514278, 514409, 548407, 546 15, 435 76
Abstract:
Compounds useful in the inhibition of HIV integrase, the prevention or treatment of infection by HIV and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in combination with other antivirals, immunomodulators, antibiotics or vaccines are described. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described. The culture Actinoplanes sp. MA7220 (ATCC 202188) is also disclosed, as well as processes for making compounds of the present invention employing the culture.

New Cyclic Fr-900520 Microbial Biotransformation Agent

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US Patent:
52906892, Mar 1, 1994
Filed:
Sep 28, 1992
Appl. No.:
7/951973
Inventors:
George M. Garrity - Westfield NJ
Magda M. Gagliardi - Somerset NJ
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
C12P 1718
C12P 104
US Classification:
435119
Abstract:
Described is a process for producing a new immunosuppressant, a C-19/C-22 cyclic hemiketal (Compound I) biotransformation analog of FR-900520, under novel fermentation conditions utilizing the novel microorganism, Streptomyces sp. (Merck Culture Collection MA6969) ATCC No. 55280. The macrolide immunosuppressant is useful in preventing human host rejection of foreign organ transplants, e. g. bone marrow, liver, lung, kidney and heart transplants.

Cyclic Fr-900520 Microbial Biotransformation Agent

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US Patent:
52682811, Dec 7, 1993
Filed:
Sep 28, 1992
Appl. No.:
7/952102
Inventors:
George M. Garrity - Westfield NJ
Magda M. Gagliardi - Somerset NJ
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
C12P 1718
C12P 104
US Classification:
435119
Abstract:
Described is a process for producing a new immunosuppressant, a C-19/C-22 cyclic hemiketal (Compound I) biotransformation analog of FR-900520, under novel fermentation conditions utilizing the novel microorganism, Streptomyces sp. (Merck Culture Collection MA6968) ATCC No. 55279. The macrolide immunosuppressant is useful in preventing human host rejection of foreign organ transplants, e. g. bone marrow, liver, lung, kidney and heart transplants.

Microorganism For Producing C-31 Desmethyl Fr-900520 Cyclic Hemiketal Immunosuppressant Agent

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US Patent:
51983583, Mar 30, 1993
Filed:
Aug 28, 1991
Appl. No.:
7/738974
Inventors:
Magda M. Gagliardi - Somerset NJ
George M. Garrity - Westfield NJ
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
C12N 100
US Classification:
4352521
Abstract:
Described is a process for producing a new immunosuppressant, a C-31 desmethyl, C-19/C-22 cyclic hemiketal biotransformation analog (Compound I) of FR-900520, under novel fermentation conditions utilizing the novel microorganism, Streptomyces, lavendulae ATCC No. 55209. Also disclosed is the C-31 methylated derivative (Compound II) of Compound I produced by enzymatic methylation using 31-O-desmethylimmunomycin O-methyl transferase, (DIMT), a methyl transferase enzyme. The macrolide immunosuppressants are useful in preventing human host rejection of foreign organ transplants, e. g. bone marrow, liver, lung, kidney and heart transplants.

Cholesterol Lowering Compound

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US Patent:
54687713, Nov 21, 1995
Filed:
Feb 2, 1994
Appl. No.:
8/190110
Inventors:
Magda M. Gagliardi - Somerset NJ
Byron H. Arison - Watchung NJ
George M. Garrity - Westfield NJ
Leeyuan Huang - Watchung NJ
John G. MacConnell - Westfield NJ
Raymond F. White - Palmyia VA
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
A61K 3135
C07D31904
US Classification:
514452
Abstract:
A compound of structural formula ##STR1## having antihypercholesterolemic utility is produced by culturing a Streptomyces sp. in a nutrient medium in the presence of a substrate of structural formula: ##STR2##.
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Magda M Gagliardi from Newtown, CT, age ~94 Get Report