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Lynne A Krummen

from San Francisco, CA
Age ~64
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Also known as:
Lynne Living Krummen, Lynne Apple Krummen, Lynne A K Apple, Lynne A Apple, Lynne A Apples, Lynne A Krumen, Lynne N
Phone and address:
3030 22Nd Ave, San Francisco, CA 94132
(415) 759-6554
Related to:
Aaron Apple, 30Raymond Apple, 64Megan Apple
Connected to:
Amber T Krummel, 48Brittany Krummen, 26Celine C Krummell, 74Darlene F Krummenacher, 74Jerry R Krummel, 65Jessie L Krummel, 61Joe Krummel, 38Julia M Krummel, 29Kurt A Krummen, 71Lacey E Krummel, 39

Lynne Krummen Phones & Addresses

  • 3030 22Nd Ave, San Francisco, CA 94132 (415) 759-6554
  • 2622 22Nd Ave, San Francisco, CA 94116
  • 3380 Sacramento St, San Francisco, CA 94118 (415) 923-9179
  • Bend, OR
  • Truckee, CA
  • South San Francisco, CA
  • Los Angeles, CA
  • Cincinnati, OH
  • 3030 22Nd Ave, San Francisco, CA 94132 (510) 655-3944

Work

Company: Vir biotechnology, inc. Apr 2018 Position: Svp, regulatory

Education

Degree: Doctorates, Doctor of Philosophy School / High School: Chatrapati Sahuji Maharaj Kanpur University, Kanpur 1984 to 1987

Industries

Biotechnology

Resumes

Resumes

Lynne Krummen Photo 1

Vice President Technical Development

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Location:
3030 22Nd Ave, San Francisco, CA 94132
Industry:
Biotechnology
Work:
Vir Biotechnology, Inc.
Svp, Regulatory
Genentech
Vice President Technical Development
Genentech
Vp, Globl Head Biologics Regulatory Cmc
Genentech 1990 - 2006
Senior Director, Process Development
Education:
Chatrapati Sahuji Maharaj Kanpur University, Kanpur 1984 - 1987
Doctorates, Doctor of Philosophy

Publications

Us Patents

Expression Vectors And Methods

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US Patent:
20050005310, Jan 6, 2005
Filed:
Nov 14, 2003
Appl. No.:
10/714000
Inventors:
Vanessa Chisholm - San Mateo CA, US
Craig Crowley - Portola Valley CA, US
Lynne Krummen - San Francisco CA, US
Yu-Ju Meng - Albany CA, US
Amy Shen - San Mateo CA, US
International Classification:
A01K067/00
C07H021/04
C12N009/06
US Classification:
800008000, 435069100, 435191000, 435325000, 536023200
Abstract:
Vectors and methods for efficient isolation of recombinant cells expressing high levels of a desired protein are provided. The vectors comprise an amplifiable selectable gene, a fluorescent protein gene, and a gene encoding a desired product in a manner that optimizes transcriptional and translational linkage.

Intron Fusion Construct And Method Of Using For Selecting High-Expressing Production Cell Lines

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US Patent:
20050019925, Jan 27, 2005
Filed:
Nov 14, 2003
Appl. No.:
10/715270
Inventors:
Lynne Krummen - San Francisco CA, US
Amy Shen - San Mateo CA, US
Vanessa Chisholm - San Mateo CA, US
Assignee:
Genentech, Inc. - South San Francisco CA
International Classification:
C12N015/63
C12N015/87
US Classification:
435455000, 435468000
Abstract:
This invention relates to a DNA construct, methods of selecting for high-expressing host cells, a method of producing a protein of interest in high yields and a method of producing eukaryotic cells having multiple copies of a sequence encoding a protein of interest. In one method, stable clones capable of producing a high level of a product of interest are generated from one step of a direct selection immediately after transfection.

Antibodies With Altered Effector Functions

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US Patent:
20050152894, Jul 14, 2005
Filed:
Sep 3, 2004
Appl. No.:
10/934087
Inventors:
Lynne Krummen - San Francisco CA, US
Dorothea Reilly - San Francisco CA, US
Stefanie Weikert - Redwood City CA, US
International Classification:
A61K039/395
C12N005/06
C07K016/46
US Classification:
424133100, 424178100, 530387300, 530391100, 435328000
Abstract:
The invention provides antibodies with altered effector functions, and methods of using these antibodies in the treatment of various diseases. The invention further provides compositions, kits and articles of manufacture for practicing methods of the invention.

Expression Vectors And Methods

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US Patent:
20070037254, Feb 15, 2007
Filed:
Sep 25, 2006
Appl. No.:
11/535038
Inventors:
Vanessa Chisholm - Bathe PA, US
Craig Crowley - Portola Valley CA, US
Lynne Krummen - San Francisco CA, US
Yu-Ju Meng - Albany CA, US
Assignee:
Genentech, Inc. - South San Francisco CA
International Classification:
C12P 21/06
C07K 14/705
C07K 14/475
C07K 14/435
C12N 9/22
C07H 21/04
C12N 5/06
US Classification:
435069100, 435456000, 435358000, 435199000, 530350000, 530388100, 530399000, 536023200
Abstract:
Vectors and methods for efficient isolation of recombinant cells expressing high levels of a desired protein are provided. The vectors comprise an amplifiable selectable gene, a fluorescent protein gene, and a gene encoding a desired product in a manner that optimizes transcriptional and translational linkage.

Expression Vectors And Methods

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US Patent:
20070054303, Mar 8, 2007
Filed:
Sep 25, 2006
Appl. No.:
11/535003
Inventors:
Vanessa Chisholm - Bathe PA, US
Craig Crowley - Portola Valley CA, US
Lynne Krummen - San Francisco CA, US
Yu-Ju Meng - Albany CA, US
Amy Shen - San Mateo CA, US
Assignee:
Genentech, Inc. - South San Francisco CA
International Classification:
C12Q 1/68
C07H 21/04
C12P 21/06
C07K 14/435
C07K 16/46
C07K 16/30
US Classification:
435006000, 435069100, 435320100, 435325000, 530350000, 536023500, 530388800, 530391100
Abstract:
Vectors and methods for efficient isolation of recombinant cells expressing high levels of a desired protein are provided. The vectors comprise an amplifiable selectable gene, a fluorescent protein gene, and a gene encoding a desired product in a manner that optimizes transcriptional and translational linkage.

Antibodies With Altered Effector Functions

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US Patent:
20070269371, Nov 22, 2007
Filed:
Feb 28, 2007
Appl. No.:
11/713577
Inventors:
Lynne Krummen - San Francisco CA, US
Dorothea Reilly - San Francisco CA, US
Stefanie Weikert - Redwood City CA, US
International Classification:
A61K 39/395
A61K 35/00
A61P 37/00
US Classification:
424001490, 424133100, 424134100, 424178100
Abstract:
The invention provides antibodies with altered effector functions, and methods of using these antibodies in the treatment of various diseases. The invention further provides compositions, kits and articles of manufacture for practicing methods of the invention.

Glycoprotein Production Process

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US Patent:
20020045207, Apr 18, 2002
Filed:
Oct 19, 1998
Appl. No.:
09/175202
Inventors:
LYNNE A. KRUMMEN - SAN FRANCISCO CA, US
MARY B. SLIWKOWSKI - SAN CARLOS CA, US
TOM WARNER - SAN CARLOS CA, US
International Classification:
C12P021/06
US Classification:
435/069100, 435/193000
Abstract:
Glycoprotein production methods and host cell lines are provided. The production methods and host cells include the functional expression of a galactosyltransferase and a sialyltransferase alone or in combination with a host cell line selected for lack of functional expression of a glycohydrolytic enzyme such as a sialidase.
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Lynne A Krummen from San Francisco, CA, age ~64 Get Report