Lynn T Vanerden

6455316, Sep 24, 2002

Apr 13, 2000

09/548848

Howard Turner - Campbell CA
G. Cameron Dales - Palo Alto CA
Lynn VanErden - Livermore CA
Johannes A. M. VanBeek - New Orleans LA
Damian A. Hajduk - San Jose CA
Ralph B. Nielsen - San Jose CA
Paul Mansky - San Francisco CA
Leonid Matsiev - Cupertino CA
Pei Wang - San Jose CA
Eric McFarland - Santa Barbara CA

Symyx Technologies, Inc. - Santa Clara CA

G01N 3110

436 37, 436 34, 436 43, 436 85, 436147, 436159, 422 62, 422104, 422196, 422197

Devices and methods for controlling and monitoring the progress and properties of multiple reactions are disclosed. The method and apparatus are especially useful for synthesizing, screening, and characterizing combinatorial libraries, but also offer significant advantages over conventional experimental reactors as well. The apparatus generally includes multiple vessels for containing reaction mixtures, and systems for controlling the stirring rate and temperature of individual reaction mixtures or groups of reaction mixtures. In addition, the apparatus may include provisions for independently controlling pressure in each vessel, and a system for injecting liquids into the vessels at a pressure different than ambient pressure. In situ monitoring of individual reaction mixtures provides feedback for process controllers, and also provides data for determining reaction rates, product yields, and various properties of the reaction products, including viscosity and molecular weight. Computer-based methods are disclosed for process monitoring and control, and for data display and analysis.

6508984, Jan 21, 2003

Jul 19, 2000

09/620310

Howard W. Turner - Campbell CA
Lynn VanErden - Livermore CA
G. Cameron Dales - Palo Alto CA
Adam Safir - Oakland CA
Ralph B. Nielsen - San Jose CA

Symyx Technologies, Inc. - Santa Clara CA

G01N 2100

422 65, 422130, 422 50, 422 681, 436 43, 436 37, 700218, 700213

A method and system for researching and developing and/or optimizing new catalysts and products in a combinatorial manner is disclosed. The method begins with starting components or a ligand library and provides methods of creating catalyst or product libraries, which are then tested in a reaction of interest. The system uses methods of robotic handling for moving libraries from station to station. The method and apparatus are especially useful for synthesizing, screening, and characterizing combinatorial catalyst libraries, but also offer significant advantages over conventional experimental methods as well.

6653138, Nov 25, 2003

Nov 28, 2000

09/728396

Howard W. Turner - Campbell CA
Lynn VanErden - Livermore CA
G. Cameron Dales - Palo Alto CA
Adam Safir - Oakland CA
Ralph B. Nielsen - San Jose CA

Symyx Technologies, Inc. - Santa Clara CA

G01N 3110

436 37, 435DIG 19, 435DIG 39, 435DIG 50, 436 43, 436164, 436166, 436174

A method and system for researching and developing and/or optimizing new catalysts and products in a combinatorial manner is disclosed. The method begins with starting components or a ligand library and provides methods of creating catalyst or product libraries, which are then tested in a reaction of interest. The system uses methods of robotic handling for moving libraries from station to station. The method and apparatus are especially useful for synthesizing, screening, and characterizing combinatorial catalyst libraries, but also offer significant advantages over conventional experimental methods as well.

6787112, Sep 7, 2004

Nov 28, 2000

09/724275

Howard Turner - Campbell CA
G. Cameron Dales - Palo Alto CA
Lynn VanErden - Livermore CA
Johannes A. M. VanBeek - New Orleans LA
Damian A. Hajduk - San Jose CA
Ralph B. Nielsen - San Jose CA
William C. Rust - Sunnyvale CA

Symyx Technologies, Inc. - Santa Clara CA

B01J 1900

422130, 422 62, 422 99, 422100, 422102, 422103, 422129, 422131, 422132, 422138, 436 43, 436 50, 436 54, 436174

Devices and methods for controlling and monitoring the progress and properties of multiple reactions are disclosed. The method and apparatus are especially useful for synthesizing, screening, and characterizing combinatorial libraries, but also offer significant advantages over conventional experimental reactors as well. The apparatus generally includes multiple vessels for containing reaction mixtures, and systems for controlling the stirring rate and temperature of individual reaction mixtures or groups of reaction mixtures. In addition, the apparatus may include provisions for independently controlling pressure in each vessel, and a system for injecting liquids into the vessels at a pressure different than ambient pressure. In situ monitoring of individual reaction mixtures provides feedback for process controllers, and also provides data for determining reaction rates, product yields, and various properties of the reaction products, including viscosity and molecular weight. Computer-based methods are disclosed for process monitoring and control, and for data display and analysis.

6864092, Mar 8, 2005

Nov 28, 2000

09/723926

Howard Turner - Campbell CA, US
G. Cameron Dales - Palo Alto CA, US
Lynn VanErden - Livermore CA, US
Johannes A. M. VanBeek - New Orleans LA, US
Damian A. Hajduk - San Jose CA, US
Ralph B. Nielsen - San Jose CA, US
Paul Mansky - San Francisco CA, US
Leonid Matsiev - Cupertino CA, US
Pei Wang - San Jose CA, US
Eric McFarland - Santa Barbara CA, US

Symyx Technologies, Inc. - Santa Clara CA

G01N031/10

436 37, 422 62, 422102, 422104, 422130, 422131, 422135, 436 85, 436147, 436159

Devices and methods for controlling and monitoring the progress and properties of multiple reactions are disclosed. The method and apparatus are especially useful for synthesizing, screening, and characterizing combinatorial libraries, but also offer significant advantages over conventional experimental reactors as well. The apparatus generally includes multiple vessels for containing reaction mixtures, and systems for controlling the stirring rate and temperature of individual reaction mixtures or groups of reaction mixtures. In addition, the apparatus may include provisions for independently controlling pressure in each vessel, and a system for injecting liquids into the vessels at a pressure different than ambient pressure. In situ monitoring of individual reaction mixtures provides feedback for process controllers, and also provides data for determining reaction rates, product yields, and various properties of the reaction products, including viscosity and molecular weight. Computer-based methods are disclosed for process monitoring and control, and for data display and analysis.

6890492, May 10, 2005

Nov 28, 2000

09/724276

Howard Turner - Campbell CA, US
G. Cameron Dales - Palo Alto CA, US
Lynn VanErden - Livermore CA, US
Johannes A. M. Van Beek - New Orleans LA, US
Damian A. Hajduk - San Jose CA, US
Ralph B. Nielsen - San Jose CA, US
Paul Mansky - San Francisco CA, US
Leonid Matsiev - Cupertino CA, US
Pei Wang - San Jose CA, US
Eric McFarland - Santa Barbara CA, US

Symyx Technologies, Inc. - Santa Clara CA

B01J019/00
B01F007/00

422130, 366244, 366249, 366251, 366252, 366273, 366279, 422131, 422135, 422138, 436 37

Devices and methods for controlling and monitoring the progress and properties of multiple reactions are disclosed. The method and apparatus are especially useful for synthesizing, screening, and characterizing combinatorial libraries, but also offer significant advantages over conventional experimental reactors as well. The apparatus generally includes multiple vessels for containing reaction mixtures, and systems for controlling the stirring rate and temperature of individual reaction mixtures or groups of reaction mixtures. In addition, the apparatus may include provisions for independently controlling pressure in each vessel, and a system for injecting liquids into the vessels at a pressure different than ambient pressure. In situ monitoring of individual reaction mixtures provides feedback for process controllers, and also provides data for determining reaction rates, product yields, and various properties of the reaction products, including viscosity and molecular weight. Computer-based methods are disclosed for process monitoring and control, and for data display and analysis.

6924149, Aug 2, 2005

Aug 28, 2002

10/229424

Howard Turner - Campbell CA, US
G. Cameron Dales - Saratoga CA, US
Lynn VanErden - Livermore CA, US
Johannes A. M. Van Beek - Amsterdam, NL
Damian A. Hajduk - San Jose CA, US
Ralph B. Nielsen - San Jose CA, US
William C. Rust - Sunnyvale CA, US

Symyx Technologies, Inc. - Santa Clara CA

G01N007/00

436148, 436 37, 436181, 422105, 422112, 422129, 422130

Devices and methods for controlling and monitoring the progress and properties of multiple reactions are disclosed. The method and apparatus are especially useful for synthesizing, screening, and characterizing combinatorial libraries, but also offer significant advantages over conventional experimental reactors as well. The apparatus generally includes multiple vessels for containing reaction mixtures, and systems for controlling the stirring rate and temperature of individual reaction mixtures or groups of reaction mixtures. In addition, the apparatus may include provisions for independently controlling pressure in each vessel, and a system for injecting liquids into the vessels at a pressure different than ambient pressure. In situ monitoring of individual reaction mixtures provides feedback for process controllers, and also provides data for determining reaction rates, product yields, and various properties of the reaction products, including viscosity and molecular weight Computer-based methods are disclosed for process monitoring and control, and for data display and analysis.

7288229, Oct 30, 2007

May 8, 2001

09/850916

Howard Turner - Campbell CA, US
G. Cameron Dales - Palo Alto CA, US
Lynn VanErden - Livermore CA, US
Johannes A. M. van Beek - Brussels, NL

Symyx Technologies, Inc. - Santa Clara CA

B01J 19/18
B01J 8/10
B01F 13/08
G01N 33/44

422130, 366273, 366274, 422 62, 422109, 422131, 422138, 436 37, 436 43, 436 85, 436147, 436159

An apparatus and method for carrying out and monitoring the progress and properties of multiple reactions is disclosed. The method and apparatus are especially useful for synthesizing, screening, and characterizing combinatorial libraries, but also offer significant advantages over conventional experimental reactors as well. The apparatus generally includes multiple vessels for containing reaction mixtures, and systems for controlling the stirring rate and temperature of individual reaction mixtures or groups of reaction mixtures. In addition, the apparatus may include provisions for independently controlling pressure in each vessel, and a system for injecting liquids into the vessels at a pressure different than ambient pressure. In situ monitoring of individual reaction mixtures provides feedback for process controllers, and also provides data for determining reaction rates, product yields, and various properties of the reaction products, including viscosity and molecular weight.