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Lois Dinterman Phones & Addresses

  • 3703 W Antioch Dr, Oxford, NC 27565
  • 416 Pine St, Oxford, NC 27565 (919) 693-7934
  • Stovall, NC
  • 87 Kings Nest Dr, Kearneysville, WV 25430 (304) 724-0013
  • 575 Nc Highway 87, Pittsboro, NC 27312 (919) 542-0194
  • Middletown, MD

Publications

Us Patents

Dendritic Cell Compositions And Methods

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US Patent:
8501470, Aug 6, 2013
Filed:
Jan 17, 2012
Appl. No.:
13/351510
Inventors:
Tamara Monesmith - Durham NC, US
Irina Tcherepanova - Rougemont NC, US
Lois Dinterman - Kearneysville WV, US
Assignee:
Argos Therapeutics, Inc. - Durham NC
International Classification:
C12N 5/07
US Classification:
435325
Abstract:
Methods are provided for the production of dendritic cells from monocytes that have been incubated at a temperature of 1 C. -34 C. for a period of approximately 6 to 96 hours from the time they are isolated from a subject. After the incubation period, the monocytes can then be induced to differentiate into dendritic cells. Mature dendritic cells made by the methods of the invention have increased levels of one or more of CD80, CD83, CD86, MHC class I molecules, or MHC class II molecules as compared to mature dendritic cells prepared from monocytes that have not been held at 1 C. -34 C. for at least 6 hours from the time they were isolated from a subject. Dendritic cells made by the methods of the invention are useful for the preparation of vaccines and for the stimulation of T cells.

Dendritic Cell Compositions And Methods

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US Patent:
20090053251, Feb 26, 2009
Filed:
Apr 7, 2006
Appl. No.:
11/918076
Inventors:
Tamara Monesmith - Durham NC, US
Irina Tcherepanova - Rougemont NC, US
Lois Dinterman - Kearneysville WV, US
International Classification:
A61K 39/00
C12N 5/08
A61P 31/00
US Classification:
4241841, 435372
Abstract:
Methods are provided for the production of dendritic cells from monocytes that have been incubated at a temperature of 1 C.-34 C. for a period of approximately 6 to 96 hours from the time they are isolated from a subject. After the incubation period, the monocytes can then be induced to differentiate into dendritic cells. Mature dendritic cells made by the methods of the invention have increased levels of one or more of CD80, CD83, CD86, MHC class I molecules, or MHC class II molecules as compared to mature dendritic cells prepared from monocytes that have not been held at 1 C.-34 C. for at least 6 hours from the time they were isolated from a subject. Dendritic cells made by the methods of the invention are useful for the preparation of vaccines and for the stimulation of T cells.

Dendritic Cell Compositions And Methods

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US Patent:
20130280805, Oct 24, 2013
Filed:
Jun 28, 2013
Appl. No.:
13/929889
Inventors:
Tamara Monesmith - Durham NC, US
Irina Tcherepanova - Rougemont NC, US
Lois Dinterman - Kearneysville WV, US
International Classification:
C12N 5/0784
US Classification:
435372, 435377
Abstract:
Methods are provided for the production of dendritic cells from monocytes that have been incubated at a temperature of 1 C.-34 C. for a period of approximately 6 to 96 hours from the time they are isolated from a subject. After the incubation period, the monocytes can then be induced to differentiate into dendritic cells. Mature dendritic cells made by the methods of the invention have increased levels of one or more of CD80, CD83, CD86, MHC class I molecules, or MHC class II molecules as compared to mature dendritic cells prepared from monocytes that have not been held at 1 C.-34 C. for at least 6 hours from the time they were isolated from a subject. Dendritic cells made by the methods of the invention are useful for the preparation of vaccines and for the stimulation of T cells.

Dendritic Cell Compositions And Methods

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US Patent:
20160102291, Apr 14, 2016
Filed:
Oct 9, 2015
Appl. No.:
14/879336
Inventors:
- Durham NC, US
Tamara Monesmith - Durham NC, US
Irina Tcherepanova - Rougemont NC, US
Lois Dinterman - Oxford NC, US
International Classification:
C12N 5/0784
Abstract:
Methods are provided for the production of dendritic cells from monocytes that have been incubated at a temperature of 1 C.-34 C. for a period of approximately 6 to 96 hours from the time they are isolated from a subject. After the incubation period, the monocytes can then be induced to differentiate into dendritic cells. Mature dendritic cells made by the methods of the invention have increased levels of one or more of CD80, CD83, CD86, MHC class I molecules, or MHC class II molecules as compared to mature dendritic cells prepared from monocytes that have not been held at 1 C.-34 C. for at least 6 hours from the time they were isolated from a subject. Dendritic cells made by the methods of the invention are useful for the preparation of vaccines and for the stimulation of T cells.

Dendritic Cell Compositions And Methods

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US Patent:
20150132844, May 14, 2015
Filed:
Jun 18, 2014
Appl. No.:
14/307991
Inventors:
- Durham NC, US
Tamara Monesmith - Durham NC, US
Irina Tcherepanova - Rougemont NC, US
Lois Dinterman - Oxford NC, US
International Classification:
C12N 5/0784
US Classification:
435347, 435377, 435372
Abstract:
Methods are provided for the production of dendritic cells from monocytes that have been incubated at a temperature of 1 C.-34 C. for a period of approximately 6 to 96 hours from the time they are isolated from a subject. After the incubation period, the monocytes can then be induced to differentiate into dendritic cells. Mature dendritic cells made by the methods of the invention have increased levels of one or more of CD80, CD83, CD86, MHC class I molecules, or MHC class II molecules as compared to mature dendritic cells prepared from monocytes that have not been held at 1 C.-34 C. for at least 6 hours from the time they were isolated from a subject. Dendritic cells made by the methods of the invention are useful for the preparation of vaccines and for the stimulation of T cells.
Lois Moser Dinterman from Oxford, NC, age ~67 Get Report