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Liping Karen Yu

from Santa Clara, CA
Age ~61

Liping Yu Phones & Addresses

  • 734 Ridge Rd, Santa Clara, CA 95051
  • Port St Lucie, FL
  • Cupertino, CA
  • 914 Rutgers Ct, Allen, TX 75002
  • Palo Alto, CA
  • Dallas, TX
  • Port St Lucie, FL

Publications

Us Patents

Multiple Graphics Adapter Connection Systems

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US Patent:
8066515, Nov 29, 2011
Filed:
Nov 17, 2004
Appl. No.:
10/991169
Inventors:
Philip B. Johnson - Campbell CA, US
Liping Yu - Mountain View CA, US
Ludger Mimberg - San Jose CA, US
Ross F. Jatou - San Jose CA, US
Assignee:
NVIDIA Corporation - Santa Clara CA
International Classification:
H01R 12/00
US Classification:
439 61
Abstract:
A system provides a digital multi-bit connection between two or more graphics adapters. Each graphics adapter is manufactured as a printed circuit board including a finger-type edge connector. When two or more graphics adapters are installed in a system the edge connectors of each graphics adapter may be coupled to each other via a connection device that provides a portion of the digital multi-bit connection. The remainder of the digital multi-bit connection is provided by conductive traces coupling each finger of the edge connector to a graphics processing unit that is affixed to the graphics adapter. The connection device may be installed by an end-user as each additional graphics adapter is installed in the system.

Rapid Particle Detection Assay

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US Patent:
20090325192, Dec 31, 2009
Filed:
Dec 15, 2008
Appl. No.:
12/316707
Inventors:
Hrair Kirakossian - San Jose CA, US
Liping Yu - San Jose CA, US
Douglas A. Petry - San Ramon CA, US
International Classification:
G01N 33/53
G01N 21/00
G01N 33/553
G01N 33/543
US Classification:
435 72, 422 8205, 436164, 436526, 436518
Abstract:
The present invention proves instruments and methods for detecting and/or quantitating an analyte in a fluid sample. The fluid sample is placed in a sample chamber having a small, shallow detection region. The analyte is magnetically labeled using magnetic particles coated with a binding reagent, and is detectably labeled using a fluorescent dye or other detection reagent. The magnetically labeled analyte is concentrated into the detection region using a focusing magnet positioned underneath the sample chamber detection region. Concentrated analyte is measured using excitation optics positioned on top of the sample chamber detection region, adapted to illuminate only the detection region, and detection optics positioned on top of the detection region, adapted to detect only light emitted from the detection region. In a preferred embodiment, the invention provides a simple, rapid assay for measuring the concentration of CD4T cells in a whole blood sample.

Devices And Methods For Separating Magnetically Labeled Moieties In A Sample

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US Patent:
20130330739, Dec 12, 2013
Filed:
Apr 5, 2012
Appl. No.:
13/984019
Inventors:
Liping Yu - San Jose CA, US
Assignee:
BECTON, DICKINSON AND COMPANY - Franklin Lakes NJ
International Classification:
G01N 1/34
US Classification:
435 71, 422527, 4352871, 436501
Abstract:
Devices for separating magnetically labeled moieties in a sample are provided. Aspects of the devices include a magnetic field source, a first magnetic field guide having a wedge-shaped portion with an apex edge, and a second magnetic field guide having a wedge-shaped portion with an apex edge. The apex edge of the first magnetic field guide is aligned substantially across from and parallel to the apex edge of the second magnetic field guide, and the device is configured to separate magnetically labeled moieties from non-magnetically labeled moieties in the sample. Also provided are methods of using the devices, as well as systems and kits configured for use with the devices and methods.

High-Throughput Single-Cell Analysis Combining Proteomic And Genomic Information

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US Patent:
20210395817, Dec 23, 2021
Filed:
Jul 14, 2021
Appl. No.:
17/375377
Inventors:
- Franklin Lakes NJ, US
Liping Yu - San Jose CA, US
International Classification:
C12Q 1/6874
C12Q 1/6806
G01N 15/14
C12Q 1/6804
C12Q 1/6886
Abstract:
Disclosed herein are methods for single-cell sequencing. In some examples, the methods include enriching a sample comprising a plurality of cells for cells of interest to produce an enriched cell sample; isolating one or more cells of interest in the enriched cell sample; and obtaining sequence information of one or more polynucleotides from each of the one or more isolated cells. Obtaining sequence information may include generating a molecularly indexed polynucleotide library from the one or more isolated cells. Enriching the sample may include focusing cells of interest in the sample using acoustic focusing.

High-Throughput Single-Cell Analysis Combining Proteomic And Genomic Information

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US Patent:
20200308642, Oct 1, 2020
Filed:
Apr 30, 2020
Appl. No.:
16/863280
Inventors:
- Franklin Lakes NJ, US
Liping Yu - San Jose CA, US
International Classification:
C12Q 1/6874
C12Q 1/6806
G01N 15/14
C12Q 1/6804
C12Q 1/6886
Abstract:
Disclosed herein are methods for single-cell sequencing. In some examples, the methods include enriching a sample comprising a plurality of cells for cells of interest to produce an enriched cell sample; isolating one or more cells of interest in the enriched cell sample; and obtaining sequence information of one or more polynucleotides from each of the one or more isolated cells. Obtaining sequence information may include generating a molecularly indexed polynucleotide library from the one or more isolated cells. Enriching the sample may include focusing cells of interest in the sample using acoustic focusing.

Devices And Methods For Separating Magnetically Labeled Moieties In A Sample

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US Patent:
20180136098, May 17, 2018
Filed:
Dec 26, 2017
Appl. No.:
15/854455
Inventors:
- Franklin Lakes NJ, US
Liping Yu - San Jose CA, US
International Classification:
G01N 1/34
B03C 1/035
B03C 1/033
Abstract:
Devices for separating magnetically labeled moieties in a sample are provided. Aspects of the devices include a magnetic field source, a first magnetic field guide having a wedge-shaped portion with an apex edge, and a second magnetic field guide having a wedge-shaped portion with an apex edge. The apex edge of the first magnetic field guide is aligned substantially across from and parallel to the apex edge of the second magnetic field guide, and the device is configured to separate magnetically labeled moieties from non-magnetically labeled moieties in the sample. Also provided are methods of using the devices, as well as systems and kits configured for use with the devices and methods.

Devices And Methods For Acoustic Particle Separation

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US Patent:
20170363522, Dec 21, 2017
Filed:
Jun 1, 2017
Appl. No.:
15/611651
Inventors:
- Franklin Lakes NJ, US
Liping Yu - San Jose CA, US
International Classification:
G01N 1/40
B01L 3/00
Abstract:
Aspects of the present disclosure include an acoustic separator for acoustically separating components of a sample, such as a biological sample. Acoustic separators according to certain embodiments include an acoustic field generator soldered to a flow channel having a fluid flow path where the acoustic field generator produces an acoustic field in the fluid flow path. Methods of soldering an acoustic field generator to a flow channel having a fluid flow path are also described. Methods for acoustically separating components of a sample as well as systems and kits, including one or more acoustic separators, suitable for practicing the subject methods are also provided.

Devices And Methods For Processing A Biological Sample

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US Patent:
20150177111, Jun 25, 2015
Filed:
Dec 11, 2014
Appl. No.:
14/567892
Inventors:
- Franklin Lakes NJ, US
Liping Yu - San Jose CA, US
Smita Ghanekar - Fremont CA, US
Jianying Cao - San Jose CA, US
International Classification:
G01N 1/40
G01N 15/14
G01N 1/28
Abstract:
Aspects of the present disclosure include methods for processing a biological sample. Methods according to certain embodiments include disrupting a biological sample to produce a disrupted biological sample and acoustically separating larger components from smaller components in the disrupted biological sample. In certain embodiments, methods may include monitoring aggregation while the biological sample is being processed. Methods, in certain instances, also include acoustically separating cells from cellular debris and non-cellular macromolecules as well as magnetically separating magnetically labelled moieties from unlabeled moieties. Systems, including a disrupter, one or more acoustic concentrator devices, feedback monitors and magnetic separation devices suitable for practicing the subject methods are also described.
Liping Karen Yu from Santa Clara, CA, age ~61 Get Report