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Lina Q Setti

from Fremont, CA
Age ~65
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Related to:
Sandra L Setti, 40Gabriel Setti, 38Andres Setti, 34Eduardo Setti, 68
Connected to:
Maria F Setti, 51Mary T Setti, 71Patricia B Setti, 42Patricia Settimelli, 91Alessandro Settimi, 47Harry A Settimi, 66Tellie E Settimi, 77Nita M Settina, 60William A Settina, 58Glenn R Setting, 53

Lina Setti Phones & Addresses

  • 320 Paloma Ter, Fremont, CA 94536 (650) 303-2783
  • 804 Delaware St, San Mateo, CA 94401 (650) 579-2718
  • Nutley, NJ
  • 320 Paloma Ter, Fremont, CA 94536 (650) 579-2718

Work

Company: Global blood therapeutics Jun 1, 2014 Position: Scientist i

Education

Degree: Masters School / High School: University of Alberta 1993 to 1997 Specialities: Organic Chemistry

Skills

Purification • Medicinal Chemistry • Small Molecules • Pharmaceutical Industry • Organic Synthesis • Protein Chemistry • Drug Discovery • Organic Chemistry • Nmr • Characterization • Drug Design • Lc Ms • Hplc • Drug Development • Chemical Synthesis • Inflammation • Biotechnology • Lead Change • Liquid Chromatography Mass Spectrometry • High Performance Liquid Chromatography

Languages

Spanish

Industries

Pharmaceuticals

Resumes

Resumes

Lina Setti Photo 1

Scientist I

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Location:
San Francisco, CA
Industry:
Pharmaceuticals
Work:
Global Blood Therapeutics
Scientist I
Novartis Aug 2010 - Jun 2014
Scientist I
Roche 1999 - Nov 2009
Medicinal Chemist -Research Associate Iii
Roche 1998 - 1999
Research Associate I
Naeja Pharmaceutical Inc. 1997 - 1997
Research Associate
Education:
University of Alberta 1993 - 1997
Masters, Organic Chemistry
Skills:
Purification
Medicinal Chemistry
Small Molecules
Pharmaceutical Industry
Organic Synthesis
Protein Chemistry
Drug Discovery
Organic Chemistry
Nmr
Characterization
Drug Design
Lc Ms
Hplc
Drug Development
Chemical Synthesis
Inflammation
Biotechnology
Lead Change
Liquid Chromatography Mass Spectrometry
High Performance Liquid Chromatography
Languages:
Spanish

Publications

Us Patents

Pyrimido[5,4-E] [1,2,4]Triazine-5, 7-Diamine Compounds As Protein Tyrosine Phosphatase Inhibitors

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US Patent:
20030153756, Aug 14, 2003
Filed:
Dec 10, 2002
Appl. No.:
10/315769
Inventors:
Kevin Guertin - Verona NJ, US
Lina Setti - San Mateo CA, US
International Classification:
C07D487/02
US Classification:
544/184000
Abstract:
The invention relates to pyrimido[5,4-e][1,2,4]triazine-5,7-diamine compounds which are useful for inhibiting protein tyrosine phosphatases, particularly PTP1B.

Tricyclic Compounds As Histone Methyltransferase Inhibitors

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US Patent:
20200361896, Nov 19, 2020
Filed:
Aug 13, 2018
Appl. No.:
16/639047
Inventors:
- SOUTH SAN FRANCISCO CA, US
Zhe LI - San Diego CA, US
Qing XU - Foster City CA, US
Calvin YEE - Daly City CA, US
Lina SETTI - Fremont CA, US
Hing SHAM - Palo Alto CA, US
International Classification:
C07D 401/12
C07D 221/22
C07D 221/06
C07D 471/04
C07D 401/14
Abstract:
The present disclosure provides tricyclic compounds of formula (I) that are histone methyltransferases G9a and/or GLP inhibitors and are therefore useful for the treatment of diseases treatable by inhibition of G9a and/or GLP such as cancers and hemoglobinopathies (e.g., beta-thalassemia and sickle cell disease). Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.

Biaryl Amide Compounds As Kinase Inhibitors

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US Patent:
20190175606, Jun 13, 2019
Filed:
Feb 12, 2019
Appl. No.:
16/274165
Inventors:
- Basel, CH
Paul Andrew BARSANTI - Pleasant Hill CA, US
Matthew T. BURGER - Cambridge MA, US
Michael Patrick DILLON - Castro Valley CA, US
Alan DIPESA - Boston MA, US
Cheng HU - San Mateo CA, US
Yan LOU - Pleasanton CA, US
Gisele A. NISHIGUCHI - Arlington MA, US
Yue PAN - Lexington MA, US
Valery Rostislavovich POLYAKOV - Moraga CA, US
Savithri RAMURTHY - Walnut Creek CA, US
Alice C. RICO - Castro Valley CA, US
Lina Quattrocchio SETTI - Fremont CA, US
Aaron SMITH - Fremont CA, US
Sharadha SUBRAMANIAN - San Ramon CA, US
Benjamin R. TAFT - Emeryville CA, US
Huw Roland TANNER - San Francisco CA, US
Lifeng WAN - Emeryville CA, US
Naeem YUSUFF - Cambridge MA, US
International Classification:
A61K 31/5377
C07D 493/10
C07D 403/12
C07D 413/14
C07D 413/12
C07D 403/04
C07D 401/12
C07D 277/42
C07D 239/48
C07D 239/47
C07D 239/42
C07D 237/20
C07D 213/74
A61K 45/06
A61K 31/541
C07D 413/04
C07D 491/08
C07B 59/00
C07D 417/12
C07D 237/24
C07D 491/04
A61K 31/444
A61K 31/501
C07D 513/04
C07D 491/048
A61K 31/5375
C07D 213/81
C07D 213/82
C07D 213/84
C07D 237/22
C07D 409/14
C07D 498/08
C07D 495/04
C07D 493/04
C07D 491/107
C07D 263/58
C07D 487/04
C07D 471/04
C07D 241/20
C07D 405/12
C07D 405/04
C07D 401/04
C07D 233/88
C07D 213/75
C07D 405/14
C07D 401/14
Abstract:
The present invention provides compounds of Formula (I)as described herein, and salts thereof, and therapeutic uses of these compounds for treatment of disorders associated with Raf kinase activity. The invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds and a therapeutic co-agent.

Histone Methyltransferase Inhibitors

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US Patent:
20190047981, Feb 14, 2019
Filed:
Feb 15, 2017
Appl. No.:
16/076307
Inventors:
- South San Francisco CA, US
Zhe Li - San Diego CA, US
Lina Q. Setti - Fremont CA, US
International Classification:
C07D 401/12
C07D 401/14
C07D 405/14
A61P 35/00
A61P 37/00
A61P 29/00
A61P 7/00
Abstract:
The present disclosure provides certain compounds that are histone methyltransferases G9a and/or GLP inhibitors and are therefore useful for the treatment of diseases treatable by inhibition of G9a and/or GLP such as cancers and hemoglobinpathies such as beta-thalassemia and sickle cell disease. Also provided are pharmaceutical compositions containing such compounds as well as processes and intermediates for preparing such compounds.

Bridged Bicyclic Kallikrein Inhibitors

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US Patent:
20180194780, Jul 12, 2018
Filed:
Nov 8, 2017
Appl. No.:
15/807331
Inventors:
- South San Francisco CA, US
Manuel Zancanella - San Mateo CA, US
Chul Yu - San Ramon CA, US
Lina Q. Setti - Fremont CA, US
Hing Sham - Palo Alto CA, US
Qing Xu - Foster City CA, US
Calvin W. Yee - Daly City CA, US
Ming Yu - Foster City CA, US
International Classification:
C07D 519/00
C07D 493/08
C07D 491/18
C07D 487/08
C07D 471/08
C07B 59/00
C07D 401/12
C07D 307/81
C07D 213/73
C07D 405/12
Abstract:
Provided herein are kallikrein modulating compounds, pharmaceutical compositions comprising the same, and uses thereof.

Compounds And Compositions As Raf Kinase Inhibitors

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US Patent:
20180170917, Jun 21, 2018
Filed:
Sep 11, 2015
Appl. No.:
15/510609
Inventors:
- Basel, CH
Matthew T. BURGER - Belmont MA, US
Michael Patrick DILLON - Castro Valley CA, US
Yan LOU - Pleasanton CA, US
Gisele A. NISHIGUCHI - Arlington MA, US
Savithri RAMURTHY - Emeryville CA, US
Alice C. RICO - Castro Valley CA, US
Vivek RAUNIYAR - Cambridge MA, US
Martin SENDZIK - Belmont MA, US
Sharadha SUBRAMANIAN - San Ramon CA, US
Lina Quattrocchio SETTI - Fremont CA, US
Benjamin R. TAFT - Oakland CA, US
Huw Rowland TANNER - San Francisco CA, US
Lifeng WAN - Union City CA, US
International Classification:
C07D 405/14
C07D 405/12
C07D 305/06
C07D 413/14
A61P 35/00
Abstract:
The present invention provides compounds of Formula (I) and (II) as described herein, and salts thereof, and therapeutic uses of these compounds for treatment of disorders associated with Raf kinase activity. The invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds and a therapeutic co-agent.

Biaryl Amide Compounds As Kinase Inhibitors

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US Patent:
20170260207, Sep 14, 2017
Filed:
May 22, 2017
Appl. No.:
15/601423
Inventors:
- Basel, CH
Paul Andrew BARSANTI - Pleasant Hill CA, US
Matthew T. BURGER - Cambridge MA, US
Michael Patrick DILLON - Cambridge MA, US
Alan DIPESA - Bronx NY, US
Cheng HU - San Mateo CA, US
Yan LOU - Pleasanton CA, US
Gisele A. NISHIGUCHI - Cambridge MA, US
Yue PAN - Cambridge MA, US
Valery Rostislavovich POLYAKOV - Emeryville CA, US
Savithri RAMURTHY - Cambridge MA, US
Alice C. RICO - Emeryville CA, US
Lina Quattrocchio SETTI - Fremont CA, US
Aaron SMITH - Emeryville CA, US
Sharadha SUBRAMANIAN - Emeryville CA, US
Benjamin R. TAFT - Emeryville CA, US
Huw Roland TANNER - San Francisco CA, US
Lifeng WAN - Emeryville CA, US
Naeem YUSUFF - Cambridge MA, US
International Classification:
C07D 513/04
A61K 31/5377
C07D 213/74
C07D 237/22
C07D 213/84
C07D 213/81
C07D 213/75
C07D 401/14
C07D 405/14
C07D 413/12
C07D 413/14
C07D 491/08
A61K 31/444
C07D 241/20
C07D 401/04
C07D 237/24
C07D 237/20
A61K 31/501
C07D 239/48
C07D 403/04
C07D 487/04
C07D 471/04
C07D 263/58
C07D 495/04
C07D 491/04
C07D 409/14
C07D 413/04
C07B 59/00
C07D 401/12
Abstract:
The present invention provides compounds of Formula (I) as described herein, and salts thereof, and therapeutic uses of these compounds for treatment of disorders associated with Raf kinase activity. The invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds and a therapeutic co-agent.

Bridged Bicyclic Kallikrein Inhibitors

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US Patent:
20160362427, Dec 15, 2016
Filed:
Jun 9, 2016
Appl. No.:
15/177641
Inventors:
- South San Francisco CA, US
Manuel Zancanella - San Mateo CA, US
Chul Yu - San Ramon CA, US
Lina Setti - Fremont CA, US
Hing Sham - Palo Alto CA, US
Qing Xu - Foster City CA, US
Calvin Yee - Daly City CA, US
Ming Yu - Foster City CA, US
International Classification:
C07D 519/00
C07D 405/12
C07D 307/81
C07D 491/18
C07B 59/00
C07D 401/12
C07D 487/08
C07D 471/08
C07D 493/08
C07D 213/73
Abstract:
Provided herein are kallikrein modulating compounds, pharmaceutical compositions comprising the same, and uses thereof.
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Lina Q Setti from Fremont, CA, age ~65 Get Report