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Laurent B Giovangrandi

from Palo Alto, CA
Age ~52
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Also known as:
Laurent C Giovangrandi
Phone and address:
663 Channing Ave, Palo Alto, CA 94301
(650) 838-9454
Related to:
C GiovangrandiAnne C Giovangrandi, 54L B Giovangrandi, 52Charlotte GiovangrandiL Giovangrandi, 43
Connected to:
Angelo D Giovanetti, 84Arthur P Giovanetti, 49Claire E Giovanetti, 98Donato Giovanetti, 28Ellen G Giovanelli, 57Ernest J Giovanelli, 75Marco Giovanelli, 41Michael P Giovando, 57Molly M Giovanetti, 58Stephanie O Giovanetti, 63

Laurent Giovangrandi Phones & Addresses

  • 663 Channing Ave, Palo Alto, CA 94301 (650) 838-9454
  • Stanford, CA

Work

Company: Physiowave Jun 2016 Position: Chief technology officer, co-founder

Education

Degree: Doctorates, Doctor of Philosophy School / High School: Swiss Federal Institute of Technology (Epfl) 1995 to 1999

Skills

Biosensors • Biomedical Engineering • Electrophysiology • Assay Development • Nanotechnology • Mems • Signal Processing • Biomems • Medical Devices

Industries

Research

Resumes

Resumes

Laurent Giovangrandi Photo 1

Chief Technology Officer, Co-Founder

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Location:
Palo Alto, CA
Industry:
Research
Work:
Physiowave
Chief Technology Officer, Co-Founder
Education:
Swiss Federal Institute of Technology (Epfl) 1995 - 1999
Doctorates, Doctor of Philosophy Swiss Federal Institute of Technology (Epfl) 1973 - 1978
Doctorates, Doctor of Philosophy
Skills:
Biosensors
Biomedical Engineering
Electrophysiology
Assay Development
Nanotechnology
Mems
Signal Processing
Biomems
Medical Devices

Publications

Us Patents

Low Cost Fabrication Of Microelectrode Arrays For Cell-Based Biosensors And Drug Discovery Methods

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US Patent:
20060057771, Mar 16, 2006
Filed:
Mar 10, 2005
Appl. No.:
11/078904
Inventors:
Gregory Kovacs - Palo Alto CA, US
Laurent Giovangrandi - Palo Alto CA, US
International Classification:
H01L 21/50
H01L 21/48
C12M 1/34
US Classification:
438106000, 435287100
Abstract:
A method for making a plurality of low-cost microelectrode arrays (MEAs) on one substrate utilizing certain unmodified printed circuit board (PCB) fabrication processes and selected materials. In some embodiments, a MEA device is composed of a thin polymer substrate containing patterned conductive traces. Coverlays on both sides of the substrate insulate the conductive traces and defines the electrodes. Preferably, flexible PCB technology is utilized to simultaneously define the microelectrode arrays. In an embodiment, the sensor is an integrated temperature sensor/heater in which the MEA device operates to record extracellular electrical signals from electrically active cell cultures. The present invention enables economical and efficient mass production of MEA devices, making them particularly suitable for disposable applications such as drug discovery, biosensors, etc.

Systems And Methods For Monitoring Heart Function

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US Patent:
20100094147, Apr 15, 2010
Filed:
Oct 14, 2009
Appl. No.:
12/579264
Inventors:
Omer T. Inan - Palo Alto CA, US
Mozziyar Etemadi - San Francisco CA, US
Laurent B. Giovangrandi - Palo Alto CA, US
Gregory T. Kovacs - Palo Alto CA, US
Richard M. Wiard - San Jose CA, US
International Classification:
A61B 5/02
A61B 5/04
US Classification:
600500, 600509
Abstract:
Characteristics of a user's heart are detected. In accordance with an example embodiment, a ballistocardiogram (BCG) sensor is used to detect heart characteristics of a user, and provide a BCG output indicative of the detected heart characteristics. The BCG output is further processed using data from one or more additional sensors, such as to reduce noise and/or otherwise process the BCG signal to characterize the user's heart function.

Methods And System Of Determining Cardio-Respiratory Parameters

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US Patent:
20110021928, Jan 27, 2011
Filed:
Jul 14, 2010
Appl. No.:
12/836572
Inventors:
Laurent Giovangrandi - Palo Alto CA, US
Omer T. Inan - Palo Alto CA, US
Keya R. Pandia - Stanford CA, US
Assignee:
The Boards of Trustees of the Leland Stanford Junior University - Palo Alto CA
International Classification:
A61B 5/0205
US Classification:
600484
Abstract:
Embodiments of the present invention provide noninvasive methods and systems of determining and monitoring an individual's respiration pattern, respiration rate, other cardio-respiratory parameters or variations thereof.

Enhanced Microfluidic Electromagnetic Measurements

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US Patent:
20120084022, Apr 5, 2012
Filed:
Sep 30, 2011
Appl. No.:
13/250605
Inventors:
Laurent Giovangrandi - Palo Alto CA, US
Antonio J. Ricco - Los Gatos CA, US
Gregory Kovacs - Palo Alto CA, US
Assignee:
The Board of Trustees of the Leland Stanford Junior University - Palo Alto CA
International Classification:
G01F 1/58
G06F 19/00
US Classification:
702 45, 7386112
Abstract:
Techniques for enhanced microfluidic impedance spectroscopy include causing a core fluid to flow into a channel between two sheath flows of one or more sheath fluids different from the core fluid. Flow in the channel is laminar. A dielectric constant of a fluid constituting either sheath flow is much less than a dielectric constant of the core fluid. Electrical impedance is measured in the channel between at least a first pair of electrodes. In some embodiments, enhanced optical measurements include causing a core fluid to flow into a channel between two sheath flows of one or more sheath fluids different from the core fluid. An optical index of refraction of a fluid constituting either sheath flow is much less than an optical index of refraction of the core fluid. An optical property is measured in the channel.

Systems And Methods For Monitoring The Circulatory System

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US Patent:
20130310700, Nov 21, 2013
Filed:
Jan 26, 2012
Appl. No.:
13/982185
Inventors:
Richard M. Wiard - Campbell CA, US
Laurent B. Giovangrandi - Palo Alto CA, US
Gregory T. Kovacs - Palo Alto CA, US
Assignee:
The Board of Trustees of the Leland Stanford Junior University - Palo Alto CA
International Classification:
A61B 5/02
A61B 5/11
A61B 5/0402
A61B 5/021
US Classification:
600485, 600500
Abstract:
In accordance with embodiments of the present disclosure, a ballistocardiogram (BCG) sensor is used to detect heart and vascular characteristics of a user, and provide a BCG output indicative of the detected cardiovascular characteristics. The BCG output can be used for various purposes, such as detecting arterial aging. Secondary sensors can be used in conjunction with the BCG and can be used to determine the central arterial blood pressure, when used in conjunction with a peripheral blood pressure measurement.

Motion Artifact Mitigation Methods And Devices For Pulse Photoplethysmography

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US Patent:
20140058217, Feb 27, 2014
Filed:
Aug 23, 2013
Appl. No.:
13/974758
Inventors:
Laurent B. Giovangrandi - Palo Alto CA, US
Assignee:
The Board of Trustees of the Leland Stanford Junior University - Palo Alto CA
International Classification:
A61B 5/0295
US Classification:
600301, 600322
Abstract:
Aspects of the present disclosure are directed toward devices, apparatus, and methods for interfacing a PPG apparatus with the skin surface of a patient and sensing artifacts due to surface motion attributable to contact-based surface motion at or near where the apparatus in contact with the skin surface of the patient. The devices, apparatus, and methods include circuitry that contacts the skin surface of the patient, illuminates tissue at the surface, and senses a pulse photoplethysmography (PPG) signal of the patient in response thereto. Further, the circuitry senses artifacts due to surface motion, and responds to the sensed PPG signal by processing the sensed PPG signal relative to the sensed artifacts to produce a version of the sensed PPG signal that is indicative local blood volume and composition of the patient, and filtered to suppress noise therein due to the contact-based surface motion.

Non-Invasive Assessment Of Glymphatic Flow And Neurodegeneration From A Wearable Device

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US Patent:
20230080140, Mar 16, 2023
Filed:
Oct 4, 2022
Appl. No.:
17/937952
Inventors:
- Los Altos Hills CA, US
Gregory T.A. Kovacs - Palo Alto CA, US
Laurent B. Giovangrandi - Palo Alto CA, US
Carl J. Weber - Portola Valley CA, US
Joerg C. Student - San Francisco CA, US
Nathan Whipple - San Francisco CA, US
Jonathan I. Kaplan - Palo Alto CA, US
International Classification:
A61B 5/00
A61B 5/0205
A61B 5/372
Abstract:
A computer-implemented method and system includes accessing neurophysiological and neurovascular data recorded during sleep. A function mapping is executed from said neurophysiological and neurovascular data to a target that is one of a glymphatic flow marker, a molecular analysis marker of neurodegeneration, or a neuroimaging marker of neurodegeneration. A target prediction model is output based on the function mapping. The target prediction model can receive new neurophysiological and neurovascular data and output a predicted marker of neurodegeneration.

Multifunction Scale With Large-Area Display

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US Patent:
20170211968, Jul 27, 2017
Filed:
Feb 6, 2017
Appl. No.:
15/425737
Inventors:
- Santa Clara CA, US
Richard M. Wiard - Campbell CA, US
Laurent B. Giovangrandi - Palo Alto CA, US
International Classification:
G01G 19/50
G01G 21/28
G01G 23/36
G01G 23/38
A61B 5/00
A61B 5/053
A61B 5/024
A61B 5/0245
G01G 21/22
G01G 19/52
A61B 5/1171
Abstract:
Weighing scale apparatuses (devices and systems) and methods are implemented using a variety of biometric-based devices and methods. According to one such implementation, a weighing scale uses a base unit to integrate a support structure, a display, and circuitry to measure and determine the physiological parameters of the user, including a user-weight metric. The support structure includes a platform region that utilizes sensor circuitry to collect physiological data from the user, which is then processed by user-targeted circuitry to determine the physiological parameters (e.g., weight and heart-related measurements) of the user. Such parameters are then associated with the user and saved to a data-access circuit, and also forwarded to a display which communicates the physiological parameters among other information to the user through the platform region; the display encompassing substantially all of the platform region, including the region(s) upon which the user would stand for weight measurements.
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Laurent B Giovangrandi from Palo Alto, CA, age ~52 Get Report