Resumes
Resumes
Larry Benowitz Phones & Addresses
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45 Moreland Ave, Newton Center, MA 02459 (617) 244-4130 (617) 969-7524
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Newton, MA
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Lowell, MA
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Pasadena, CA
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45 Moreland Ave, Newton, MA 02459 (617) 218-7887
Work
Position:
Financial Professional
Education
Degree:
High school graduate or higher
Publications
Us Patents
Methods For Modulating The Axonal Outgrowth Of Central Nervous System Neurons
View pageUS Patent:
6440455, Aug 27, 2002
Filed:
Sep 2, 1997
Appl. No.:
08/921902
Inventors:
Larry I. Benowitz - Newton Centre MA
Assignee:
Childrens Medical Center Corporation - Boston MA
International Classification:
A61K 9127
US Classification:
424450, 424422, 424423, 424484, 424486, 424489, 424490, 424497, 514 45
Abstract:
Methods for modulating the axonal outgrowth of central nervous system neurons are provided. Methods for stimulating the axonal outgrowth of central nervous system neurons following an injury (e. g. , stroke, Traumatic Brain Injury, cerebral aneurism, spinal cord injury and the like) and methods for inhibiting the axonal outgrowth of central nervous system neurons are also provided. Finally, a packed formulation comprising a pharmaceutical composition comprising an inosine nucleoside and a pharmaceutically acceptable carrier packed with instructions for use of the pharmaceutical composition for treatment of a central nervous system disorder is provided.
Methods For Modulating The Axonal Outgrowth Of Central Nervous System Neurons
View pageUS Patent:
6551612, Apr 22, 2003
Filed:
Nov 29, 2001
Appl. No.:
09/997688
Inventors:
Larry I. Benowitz - Newton Centre MA
Assignee:
Childrens Medical Center Corporation - Boston MA
International Classification:
A61K 9127
US Classification:
424450, 424422, 424423, 424484, 424486, 424489, 424490, 424497, 514 45
Abstract:
Methods for modulating the axonal outgrowth of central nervous system neurons are provided. Methods for stimulating the axonal outgrowth of central nervous system neurons following an injury (e. g. , stroke, Traumatic Brain Injury, cerebral aneurism, spinal cord injury and the like) and methods for inhibiting the axonal outgrowth of central nervous system neurons are also provided. Finally, a packed formulation comprising a pharmaceutical composition comprising an inosine nucleoside and a pharmaceutically acceptable carrier packed with instructions for use of the pharmaceutical composition for treatment of a central nervous system disorder is provided.
Methods And Compositions For Treating Ocular Disorders
View pageUS Patent:
6855690, Feb 15, 2005
Filed:
Nov 14, 2002
Appl. No.:
10/294965
Inventors:
Larry I. Benowitz - Newton MA, US
Assignee:
Children's Medical Center Corporation - Boston MA
International Classification:
A61K038/00
A61K038/16
A61K038/16
US Classification:
514 2, 514 12, 514912, 514913
Abstract:
The present invention provides a method for treating and/or preventing damage to a retina or optic nerve in a subject comprising administering to the subject a therapeutically effective amount of oncomodulin. Preferably, the subject is a mammal, most preferably, a human. In preferred embodiments, the oncomodulin may be used in combination with mannose, a mannose derivative and/or inosine.
Methods And Compositions For Modulating Axonal Outgrowth Of Central Nervous System Neurons
View pageUS Patent:
7172871, Feb 6, 2007
Filed:
Sep 7, 2000
Appl. No.:
09/656915
Inventors:
Larry I. Benowitz - Newton Centre MA, US
Assignee:
Children's Medical Center Corporation - Boston MA
International Classification:
G01N 33/00
US Classification:
435 71, 435 4, 435375
Abstract:
Methods and compositions for modulating the axonal outgrowth of central nervous system neurons are provided. Methods for stimulating the axonal outgrowth of central nervous system neurons following an injury (e. g. , stroke, Traumatic Brain Injury, cerebral aneurism, spinal cord injury and the like) and methods for inhibiting the axonal outgrowth of central nervous system neurons in conditions such as epilepsy, e. g. , posttraumatic epilepsy, and neuropathic pain syndrome, are also provided. These methods generally involve contacting the central nervous system neurons with a compound that modulates the activity of N-kinase, or analog thereof. The methods and compositions are particularly useful for modulating the axonal outgrowth of mammalian central nervous system neurons, such as mammalian cortical neurons or retinal ganglion cells. Pharmaceutical and packaged formulations that include the compounds of the invention that modulate the activity of N-kinase are also provided.
Methods And Compositions For Treating Ocular Disorders
View pageUS Patent:
7238529, Jul 3, 2007
Filed:
Sep 3, 2004
Appl. No.:
10/933684
Inventors:
Larry I. Benowitz - Newton MA, US
Yuqin Yin - Brighton MA, US
Yuqin Yin - Brighton MA, US
Assignee:
Children's Medical Center Corporation - Boston MA
International Classification:
A61K 38/18
US Classification:
435975, 514 2, 514 12, 530350
Abstract:
The present invention provides a method for treating and/or preventing damage to a retina or optic nerve in a subject comprising administering to the subject a therapeutically effective amount of oncomodulin. Preferably, the subject is a mammal, most preferably, a human. In preferred embodiments, the oncomodulin may be used in combination with mannose, a mannose derivative and/or inosine.
Methods For Modulating The Axonal Outgrowth Of Central Nervous System Neurons
View pageUS Patent:
7338666, Mar 4, 2008
Filed:
May 19, 2005
Appl. No.:
11/132701
Inventors:
Larry I. Benowitz - Newton MA, US
International Classification:
A61K 9/127
A61K 9/16
A61K 31/52
A61K 9/16
A61K 31/52
US Classification:
424450, 514 45
Abstract:
Methods for modulating the axonal outgrowth of central nervous system neurons are provided. Methods for stimulating the axonal outgrowth of central nervous system neurons following an injury (e. g. , stroke, Traumatic Brain Injury, cerebral aneurism, spinal cord injury and the like) and methods for inhibiting the axonal outgrowth of central nervous system neurons are also provided. Finally, a packed formulation comprising a pharmaceutical composition comprising an inosine nucleoside and a pharmaceutically acceptable carrier packed with instructions for use of the pharmaceutical composition for treatment of a central nervous system disorder is provided.
Therapeutic Compositions Of Oncomodulin
View pageUS Patent:
7407937, Aug 5, 2008
Filed:
May 17, 2007
Appl. No.:
11/804295
Inventors:
Larry I. Benowitz - Newton MA, US
Yuqin Yin - Brighton MA, US
Yuqin Yin - Brighton MA, US
Assignee:
Children's Medical Center Corporation - Boston MA
International Classification:
A61K 38/18
C07K 14/475
C07K 14/475
US Classification:
514 12, 530350
Abstract:
The present invention provides a method for treating and/or preventing damage to a retina or optic nerve in a subject comprising administering to the subject a therapeutically effective amount of oncomodulin. Preferably, the subject is a mammal, most preferably, a human. In preferred embodiments, the oncomodulin may be used in combination with mannose, a mannose derivative and/or inosine.
Methods And Compositions For Treating Ocular Disorders
View pageUS Patent:
7625864, Dec 1, 2009
Filed:
Jun 30, 2008
Appl. No.:
12/164938
Inventors:
Larry I. Benowitz - Newton MA, US
Yuqin Yin - Brighton MA, US
Yuqin Yin - Brighton MA, US
Assignee:
Children's Medical Center Corporation - Boston MA
International Classification:
A61K 38/00
A61K 38/16
A61K 38/16
US Classification:
514 2, 514 12, 514912, 514913
Abstract:
The present invention provides a method for treating and/or preventing damage to a retina or optic nerve in a subject comprising administering to the subject a therapeutically effective amount of oncomodulin. Preferably, the subject is a mammal, most preferably, a human. In preferred embodiments, the oncomodulin may be used in combination with mannose, a mannose derivative and/or inosine.