US Patent:
20050113302, May 26, 2005
Inventors:
John Thompson - Warwick RI, US
David Potter - Mystic CT, US
Delvin Knight - Ledyard CT, US
Antonio Gualberto - East Greenwich CT, US
Katherine Landschulz - East Lyme CT, US
Herath Mudiyenselage Chandrasiri Herath - Abingdon, GB
Christian Rohlff - Abingdon, GB
International Classification:
A61K038/10
A61K038/08
C07K007/06
C07K007/08
US Classification:
514014000, 514015000, 514016000, 530326000, 530327000, 530328000, 530329000
Abstract:
Proteins are identified that exhibit an altered expression in mammalian cardiac tissue in response to Aagonist infusion. These proteins are termed Areceptor-mediated cardioprotective proteins (APs) and protein isoforms (APIs) and are useful as pharmaceuticals and as targets in screening methods for identifying an agent capable of modulating the expression of one or more AP and/or API.