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Katalin Kariko

from Jenkintown, PA
Age ~69

Katalin Kariko Phones & Addresses

  • 1022 Kipling Rd, Jenkintown, PA 19046 (215) 884-1923
  • Rydal, PA
  • Bethesda, MD
  • Philadelphia, PA

Work

Company: University of pennsylvania Position: Researcher

Education

Degree: Graduate or professional degree

Emails

Industries

Research

Resumes

Resumes

Katalin Kariko Photo 1

Researcher At University Of Pennsylvania

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Position:
Researcher at University of Pennsylvania, Adjunct Associate Professor at University of Pennsylvania, School of Medicine
Location:
Greater Philadelphia Area
Industry:
Research
Work:
University of Pennsylvania
Researcher

University of Pennsylvania, School of Medicine since 1989
Adjunct Associate Professor

Business Records

Name / Title
Company / Classification
Phones & Addresses
Katalin Kariko
Owner
Rna Rx
Commercial Physical Research
1022 Kipling Rd, Meadowbrook, PA 19046
(215) 884-1923
Katalin Kariko
Partner
Rnarx, LLC
Nonclassifiable Establishments · Services-Misc
175 Strafford Ave, Wayne, PA 19087

Publications

Us Patents

Rna Containing Modified Nucleosides And Methods Of Use Thereof

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US Patent:
8278036, Oct 2, 2012
Filed:
Aug 21, 2006
Appl. No.:
11/990646
Inventors:
Katalin Kariko - Rydal PA, US
Drew Weissman - Wynnewood PA, US
Assignee:
The Trustees of the University of Pennsylvania - Philadelphia PA
International Classification:
C12Q 1/68
US Classification:
435 6, 435325, 435375
Abstract:
This invention provides RNA, oligoribonucleotide, and polyribonucleotide molecules comprising pseudouridine or a modified nucleoside, gene therapy vectors comprising same, methods of synthesizing same, and methods for gene replacement, gene therapy, gene transcription silencing, and the delivery of therapeutic proteins to tissue in vivo, comprising the molecules. The present invention also provides methods of reducing the immunogenicity of RNA, oligoribonucleotide, and polyribonucleotide molecules.

Rna Preparations Comprising Purified Modified Rna For Reprogramming Cells

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US Patent:
20110143397, Jun 16, 2011
Filed:
Dec 7, 2010
Appl. No.:
12/962468
Inventors:
Katalin Kariko - Rydal PA, US
Drew Weissman - Wynnewood PA, US
Gary Dahl - Madison WI, US
Anthony Person - Madison WI, US
Judith Meis - Fitchburg WI, US
Jerome Jendrisak - Madison WI, US
International Classification:
C12N 5/071
C12P 21/00
US Classification:
435 703, 435377, 435366
Abstract:
The present invention provides compositions and methods for reprogramming somatic cells using purified RNA preparations comprising single-strand mRNA encoding an iPS cell induction factor. The purified RNA preparations are preferably substantially free of RNA contaminant molecules that: i) would activate an immune response in the somatic cells, ii) would decrease expression of the single-stranded mRNA in the somatic cells, and/or iii) active RNA sensors in the somatic cells. In certain embodiments, the purified RNA preparations are substantially free of partial mRNAs, double-stranded RNAs, un-capped RNA molecules, and/or single-stranded run-on mRNAs.

Rna Containing Modified Nucleosides And Methods Of Use Thereof

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US Patent:
20130111615, May 2, 2013
Filed:
Aug 14, 2012
Appl. No.:
13/585517
Inventors:
Katalin Kariko - Rydal PA, US
Drew Weissman - Wynnewood PA, US
International Classification:
C07H 21/02
US Classification:
800 18, 435369, 435354, 536 231, 536 232, 536 235, 424400, 514 44 R
Abstract:
This invention provides RNA, oligoribonucleotide, and polyribonucleotide molecules comprising pseudouridine or a modified nucleoside, gene therapy vectors comprising same, methods of synthesizing same, and methods for gene replacement, gene therapy, gene transcription silencing, and the delivery of therapeutic proteins to tissue in vivo, comprising the molecules. The present invention also provides methods of reducing the immunogenicity of RNA, oligoribonucleotide, and polyribonucleotide molecules.

Purification And Purity Assessment Of Rna Molecules Synthesized With Modified Nucleosides

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US Patent:
20210292786, Sep 23, 2021
Filed:
Jun 4, 2021
Appl. No.:
17/338795
Inventors:
- Philadelphia PA, US
Katalin Kariko - Rydal PA, US
International Classification:
C12N 15/85
C07K 14/505
C07K 14/52
C07H 21/02
C07K 14/475
C12P 19/34
Abstract:
This invention provides purified preparations of an RNA, oligoribonucleotide, or polyribonucleotide comprising a modified nucleoside, and methods of assessing purity of purified preparations of an RNA, oligoribonucleotide, or polyribonucleotide comprising a modified nucleoside.

Purification And Purity Assessment Of Rna Molecules Synthesized With Modified Nucleosides

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US Patent:
20170327842, Nov 16, 2017
Filed:
Jul 31, 2017
Appl. No.:
15/664036
Inventors:
- Philadelphia PA, US
Katalin Kariko - Rydal PA, US
International Classification:
C12N 15/85
C07K 14/505
C07K 14/52
C07K 14/475
C12P 19/34
C07H 21/02
A61K 48/00
Abstract:
This invention provides purified preparations of an RNA, oligoribonucleotide, or polyribonucleotide comprising a modified nucleoside, and methods of assessing purity of purified preparations of an RNA, oligoribonucleotide, or polyribonucleotide comprising a modified nucleoside.

Purification And Purity Assessment Of Rna Molecules Synthesized With Modified Nucleosides

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US Patent:
20160032316, Feb 4, 2016
Filed:
Mar 13, 2014
Appl. No.:
14/776525
Inventors:
- Philadelphia PA, US
Katalin Kariko - Rydal PA, US
Assignee:
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA - Philadelphia PA
International Classification:
C12N 15/85
C07K 14/505
C07K 14/475
C12P 19/34
C07H 21/02
Abstract:
This invention provides purified preparations of an RNA, oligoribonucleotide, or polyribonucleotide comprising a modified nucleoside, and methods of assessing purity of purified preparations of an RNA, oligoribonucleotide, or polyribonucleotide comprising a modified nucleoside.
Katalin Kariko from Jenkintown, PA, age ~69 Get Report