Katalin Ganzler

56652160, Sep 9, 1997

Oct 7, 1991

7/774044

Barry L. Karger - Newton MA
Katalin Ganzler - Melrose MA
Aharon S. Cohen - Brookline MA

Northeastern University - Boston MA

G01N 2726
G01N 27447

204605

A capillary column for high performance electrophoretic separation and detection of SDS proteins and system for using the same is disclosed. A preferred column includes a capillary, a static or dynamic layer of coating material on the inner surface of the capillary wall, and a hydrophilic polymer network which is UV-transparent in the tube, filling it. The capillary column is particularly useful in any electrophoresis system requiring UV-transparent materials.

53707770, Dec 6, 1994

May 15, 1992

7/884101

Andras Guttman - Palo Alto CA
Chia-Hui Shieh - Irvine CA
Barry L. Karger - Newton MA
Stephen J. Pentoney - Yorba Linda CA
Kenneth D. Konrad - Long Beach CA
Sushma Rampal - Yorba Linda CA
Katalin Ganzler - Melrose MA

Beckman Instruments, Inc. - Fullerton CA

G01N 2726
G01N 27447

2041828

Disclosed herein are capillary columns for capillary electrophoretic analysis of sample constituents. In an embodiment, the columns comprise a bifunctional layer comprising a positively charged amine group adsorbed to the inner wall of the capillary and an active functional group; a gel composition; hydrophilic polymer; and a separation composition capable of being removed from the column, interspersed within the remainder of the column. The disclosed columns are particularly well suited for the analysis of surfactant: proteinaceous material complexes, nucleic acid sequence, and analysis of restriction fragments according to size.