US Patent:
20040091932, May 13, 2004
Inventors:
Michelle Moore - Des Moines IA, US
Friedhelm Brinkhaus - West Des Moines IA, US
Peter Salamone - West Des Moines IA, US
Michelle Fonda - Meadow Vista CA, US
Matthew Brown - Rocklin CA, US
Karen Loser - Auburn CA, US
Ingrid Gennity - Fresno CA, US
Nicholas Everett - Meadow Vista CA, US
International Classification:
G01N033/53
C12Q001/34
Abstract:
A method of producing from sources of microorganisms enzymes having multiple improved characteristics. Soil samples are collected from a wide variety of sources that are diverse geographically and environmentally. The microorganisms are screened using microbiological screens to select microorganisms that produce enzymes that are active over a broad range of temperatures. Enzymes from selected microorganisms are screened for improved thermostability, extended active temperature range, extended active pH range, extended shelf-life, and improved protease resistance.