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Kanaka F Hettiarachchi

from Santa Clara, CA
Age ~47

Kanaka Hettiarachchi Phones & Addresses

  • 1177 Morton Ave, Santa Clara, CA
  • Irvine, CA
  • 19 Lorelei Ln, Menlo Park, CA 94025
  • San Diego, CA
  • La Jolla, CA

Publications

Us Patents

Multimodal Therapeutic Hybrid Particle Complex And System

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US Patent:
20110014297, Jan 20, 2011
Filed:
Sep 24, 2010
Appl. No.:
12/890243
Inventors:
Abraham Phillip Lee - Irvine CA, US
Kanaka Hettiarachchi - Menlo Park CA, US
Assignee:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - Oakland CA
International Classification:
A61K 9/14
A61K 9/00
A61K 38/16
A61K 38/17
A61M 37/00
US Classification:
424491, 424400, 514 212, 514 209, 604 23
Abstract:
A multiple layer microbubble drug delivery system, multiple layer microbubble drug delivery vehicle, method thereof and fabrication method are disclosed. The microfluidic drug delivery system for producing multiple layer microbubbles includes a first inlet which receives a gas and directs the gas into a central stream, a second inlet which receives a first liquid containing a drug substance and flow focuses the first liquid around the gas, a third inlet which receives a second liquid and flow focuses the second liquid around the first liquid and a fourth inlet which receives a third liquid and flow focuses the third liquid around the second liquid. The multiple layer microbubble drug delivery vehicle includes a gas core, a first liquid layer containing a drug and surrounding the gas core, a second liquid layer surrounding the first liquid layer to stabilize the first liquid layer and a plurality of particles outside the second liquid layer.

Polymer-Phospholipid Shelled Microbubbles

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US Patent:
20110045095, Feb 24, 2011
Filed:
Oct 25, 2010
Appl. No.:
12/911321
Inventors:
Kanaka Hettiarachchi - Menlo Park CA, US
Abraham Phillip Lee - Irvine CA, US
Assignee:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - Oakland CA
International Classification:
A61K 9/14
A61M 37/00
US Classification:
424497, 424490, 604 24
Abstract:
A multiple layer microfluidic system and multiple layer microbubble are disclosed. The microfluidic system for producing multiple layer microbubbles includes a first inlet which receives a gas and directs the gas into a central stream, a second inlet which receives an oil and flow focuses the oil around the gas, a third inlet which receives a polymer and lipid solution and flow focuses the polymer and lipid solution around the oil and a fourth inlet which receives a surfactant solution and flow focuses the surfactant solution around the polymer and lipid solution. The multiple layer microbubble includes a gas core, a polymer and lipid shell surrounding the gas core and a surfactant layer surrounding shell.

Multiple-Layer Microbubble Liposphere Drug Delivery Vehicle And System

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US Patent:
20090098168, Apr 16, 2009
Filed:
Oct 8, 2008
Appl. No.:
12/247782
Inventors:
Kanaka Hettiarachchi - Menlo Park CA, US
Abraham Phillip Lee - Irvine CA, US
Paul A. Dayton - Carrboro NC, US
Assignee:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - Oakland CA
International Classification:
A61K 9/00
A61M 37/00
US Classification:
424400, 604 23
Abstract:
A multiple layer microbubble drug delivery system, multiple layer microbubble drug delivery vehicle, method thereof and fabrication method is disclosed. The microfluidic drug delivery system for producing multiple layer microbubbles includes a first inlet which receives a gas and directs the gas into a central stream, a second inlet which receives a first liquid containing a drug substance and flow focuses the first liquid around the gas and a third inlet which receives a second liquid and flow focuses the second liquid around the first liquid. The multiple layer microbubble drug delivery vehicle includes a gas core, a first liquid layer containing a drug and surrounding the gas core and a second liquid layer surrounding the first liquid layer to stabilize the first liquid layer.
Kanaka F Hettiarachchi from Santa Clara, CA, age ~47 Get Report