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Jurgen Michael Lehmann

from Santa Fe, NM
Age ~65
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Also known as:
Jurgen M Lehmann, Juergen M Lehmann, Jurgen M Lehman, Juergen Lehman
Phone and address:
64 Avenida De Compadres, Santa Fe, NM 87508
(505) 983-9251
Related to:
Marcus LehmannJuergen LehmanAlmu Lehman
Connected to:
Alvin L Lehmann, 87Belinda M Lehmann, 66Bette M Lehmann, 105Brandon Lehmann, 32Brittany Lehmann, 38Brittany S Lehmann, 37Carlos A Lehmann, 59Carmen L Lehmann, 61Cherie C Lehmann, 53Chyrl A Lehmann, 58

Jurgen Lehmann Phones & Addresses

  • 64 Avenida De Compadres, Santa Fe, NM 87508 (505) 983-9251
  • 515 Centre St APT 7, Newton, MA 02458 (617) 965-1482
  • Boston, MA
  • 160 Winding Way, San Carlos, CA 94070
  • Chapel Hill, NC
  • Wichita, KS
  • Foster City, CA
  • 515 Centre St APT 7, Newton, MA 02458

Work

Company: Newco Jan 2012 Address: Greater Boston Area Position: Entrepreneur

Education

Degree: Post-doc School / High School: Burnham Institute 1989 to 1991

Skills

Molecular Biology • Drug Discovery • Lead Optimization • Cell Based Assays • High Throughput Screening • Oncology • Pharmaceuticals • R&D • Immunology • In Vitro • In Vivo • Science • Life Sciences • Cell Biology • Cell Culture • Biotechnology • Biochemistry • Protein Chemistry • Pharmaceutical Industry • Lifesciences • Biopharmaceuticals • Lead Change • Clinical Development • Medicinal Chemistry • Cell • Bioinformatics

Industries

Biotechnology

Resumes

Resumes

Jurgen Lehmann Photo 1

Drug Discovery Consultant

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Location:
Newton, MA
Industry:
Biotechnology
Work:
NewCo - Greater Boston Area since Jan 2012
Entrepreneur
Syndexa Pharmaceuticals - Greater Boston Area Sep 2006 - Sep 2011
VP of Drug Discovery
- - Strasbourg Area, France Jan 2005 - Aug 2006
Independent Consultant
CareX S.A. - Strasbourg Area, France 2001 - 2004
Chief Scientific Officer & Co-founder
Tularik - San Francisco Bay Area 1999 - 2001
Program Director
Education:
Burnham Institute 1989 - 1991
Post-doc Ludwig-Maximilians Universität München 1985 - 1989
Ph.D., Biochemistry Ludwig-Maximilians Universität München 1980 - 1985
Pharmacist, Pharmacy
Skills:
Molecular Biology
Drug Discovery
Lead Optimization
Cell Based Assays
High Throughput Screening
Oncology
Pharmaceuticals
R&D
Immunology
In Vitro
In Vivo
Science
Life Sciences
Cell Biology
Cell Culture
Biotechnology
Biochemistry
Protein Chemistry
Pharmaceutical Industry
Lifesciences
Biopharmaceuticals
Lead Change
Clinical Development
Medicinal Chemistry
Cell
Bioinformatics

Business Records

Name / Title
Company / Classification
Phones & Addresses
Jurgen Lehmann
Vice President R And D
Syndexa Pharmaceuticals
Pharmaceutical Preparations
767 Concord Ave, Cambridge, MA 02138
Jurgen Lehmann
Vice President R And D
Syndexa Pharmaceuticals
767 Concord Ave, Cambridge, MA 02138
(617) 349-1660
Jurgen Lehmann
Sales And Marketing Executive
SYNDEXA SECURITY CORPORATION
Mfg Pharmaceutical Preparations
480 Arsenal St, Watertown, MA 02472
Jurgen Lehmann
Vice President R And D
Syndexa Pharmaceuticals
Pharmaceutical Preparations
767 Concord Ave, Cambridge, MA 02138

Publications

Us Patents

Use Of Fxr Ligands

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US Patent:
6984650, Jan 10, 2006
Filed:
Aug 8, 2003
Appl. No.:
10/637190
Inventors:
Curt Dale Haffner - Durham NC, US
Patrick Reed Maloney - Durham NC, US
Timothy Mark Willson - Durham NC, US
Steven Gerard Blanchard - Durham NC, US
Steven A. Kliewer - Dallas TX, US
Jurgen M. Lehmann - San Carlos CA, US
Derek James Parks - Durham NC, US
Julie Beth Stimmel - Durham NC, US
Assignee:
Smithkline Beecham Corporation - Philadelphia PA
International Classification:
A61K 31/415
US Classification:
514340, 514378
Abstract:
The present invention includes nuclear receptor heterodimer and nuclear receptor-coactivator peptide assays for identifying ligands for nuclear receptors, utilizing scintillation proximity and fluorescence resonance energy transfer (FRET), and methods of using identified ligands.

Car Modulators: Screening And Treatment Of Hypercholesterolemia

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US Patent:
20020152479, Oct 17, 2002
Filed:
Jan 12, 2001
Appl. No.:
09/760364
Inventors:
Jurgen Lehmann - San Carlos CA, US
Andrew Shiau - San Francisco CA, US
International Classification:
A61K031/57
G01N033/00
A01K067/00
US Classification:
800/003000, 514/177000
Abstract:
This invention provides methods that are useful for identifying therapeutic agents for the treatment of a CAR-mediated disorder or condition. The methods include determining whether the candidate therapeutic agent can: interact directly with CAR, modulate CAR-mediated gene expression, decrease CAR antagonist elevation of a cholesterol indicator in a mammal, or decrease a cholesterol level indicator in a mammal with a defective CAR. Also provided are CAR agonists.

Activators Of The Nuclear Orphan Receptor Peroxisome Proliferator-Activated Receptor Gamma

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US Patent:
59945540, Nov 30, 1999
Filed:
Dec 9, 1998
Appl. No.:
9/207936
Inventors:
Steven Anthony Kliewer - Cary NC
Jurgen M. Lehmann - Chapel Hill NC
Timothy M. Willson - Durham NC
Assignee:
Glaxo Wellcome Inc. - Research Triangle Park NC
International Classification:
C09D491052
G01N 3353
C07D40310
US Classification:
548183
Abstract:
The present invention provides radiolabeled 5-{4-[2-(Methyl-pyridine-2-yl-amino)-ethoxy]-benzyl}-thiazolidine-2,4-dion e. In another aspect, the present invention provides a method for determining whether a compound does or does not interact directly with PPAR-gamma, comprising the step of specifically binding a radiolabeled compound of this invention to the ligand binding domain of PPAR-gamma.

Bridged Bicyclic Aromatic Compounds And Their Use In Modulating Gene Expression Of Retinoid Receptors

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US Patent:
54668611, Nov 14, 1995
Filed:
Nov 25, 1992
Appl. No.:
7/982305
Inventors:
Marcia L. Dawson - Menlo Park CA
James F. Cameron - Palo Alto CA
Peter D. Hobbs - Moss Beach CA
Ling Jong - Sunnyvale CA
Magnus Pfahl - Solana Beach CA
Jurgen M. Lehmann - Solana Beach CA
Assignee:
SRI International - Menlo Park CA
La Jolla Cancer Research Foundation - La Jolla CA
International Classification:
C07C 6976
C07C 6336
US Classification:
560100
Abstract:
Bridged bicyclic aromatic compounds are provided having the structure ##STR1## wherein R. sup. 1, R. sup. 2, R. sup. 3, R. sup. 4, R. sup. 5 and n are as defined herein. The novel compounds are useful for modulating gene expression of retinoic acid receptors, vitamin D receptors and thyroid receptors. Pharmaceutical compositions and methods for modulating gene expression are provided as well.

Bridged Bicyclic Aromatic Compounds And Their Use In Modulating Gene Expression Of Retinoid Receptors

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US Patent:
58377255, Nov 17, 1998
Filed:
May 24, 1995
Appl. No.:
8/448991
Inventors:
Marcia I. Dawson - Menlo Park CA
James F. Cameron - Palo Alto CA
Peter D. Hobbs - Moss Beach CA
Ling Jong - Sunnyvale CA
Magnus Pfahl - Solana Beach CA
Jurgen M. Lehmann - Solana Beach CA
Assignee:
SRI International - Menlo Park CA
La Jolla Cancer Research Foundation - La Jolla CA
International Classification:
A61K 31335
A61K 3138
C07D31700
C07D33902
US Classification:
514467
Abstract:
Bridged bicyclic aromatic compounds are provided having the structure ##STR1## wherein R. sup. 1, R. sup. 2, R. sup. 3, R. sup. 4, R. sup. 5 and n are as defined herein. The novel compounds are useful for modulating gene expression of retinoic acid receptors, vitamin D receptors and thyroid receptors. Pharmaceutical compositions and methods for modulating gene expression are provided as well.

Activators Of The Nuclear Orphan Receptor Peroxisome Proliferator-Activated Receptor Gamma

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US Patent:
59027266, May 11, 1999
Filed:
Feb 25, 1998
Appl. No.:
9/028988
Inventors:
Steven Anthony Kliewer - Cary NC
Jurgen M. Lehmann - Chapel Hill NC
Timothy M. Willson - Durham NC
Assignee:
Glaxo Wellcome Inc. - Research Triangle Park NC
International Classification:
G01N33/53
US Classification:
435 71
Abstract:
The present invention provides activator compounds, including agonists, to the peroxisome proliferator-activated receptor gamma. Particular PPAR. gamma. activators are set forth, as are a pharmaceutical composition for treating diabetes, non-insulin-dependent diabetes mellitus, cardiovascular disorders, and methods for such treatment.

Isbn (Books And Publications)

Italienische, Franzosische Und Spanische Gemalde Des 16. Bis 18. Jahrhunderts

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Author

Jurgen M. Lehmann

ISBN #

3921566088

Italienische, Franzosische Und Spanische Meister in Der Kasseler Gemaldegalerie

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Author

Jurgen M. Lehmann

ISBN #

3925050027

Das Nord- Und Ostseeaquarium: Besatz, Einrichtung U. Pflege

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Author

Jurgen Lehmann

ISBN #

3440045455

Bekennen, Erzahlen, Berichten: Studien Zu Theorie Und Geschichte Der Autobiographie

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Author

Jurgen Lehmann

ISBN #

3484180986

Der Einfluss Der Philosophie Des Deutschen Idealismus in Der Russischen Literaturkritik Des 19. Jahrhunderts: D. organ. Kritik Apollon A. Grigorevs

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Author

Jurgen Lehmann

ISBN #

3533024695

Der Einfluss Der Philosophie Des Deutschen Idealismus in Der Russischen Literaturkritik Des 19. Jahrhunderts: D. organ. Kritik Apollon A. Grigorevs

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Author

Jurgen Lehmann

ISBN #

3533024709

Konflikt, Grenze, Dialog: Kulturkontrastive Und Interdisziplinare Textzugange Festschrift Fur Horst Turk Zum 60. Geburtstag

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Author

Jurgen Lehmann

ISBN #

3631308256

Simulations- Und Planspiele in Der Schule

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Author

Jurgen Lehmann

ISBN #

3781503224

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Jurgen Michael Lehmann from Santa Fe, NM, age ~65 Get Report