Junfa Fan Phones & Addresses
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Santa Clara, CA
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Palo Alto, CA
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917 Catamaran St, Foster City, CA 94404
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777 Shell Blvd, Foster City, CA 94404
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910 Farragut St, Pittsburgh, PA 15206
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201 Conant Rd, Rochester, NY 14623
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San Francisco, CA
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Rockville, MD
Publications
Us Patents
Phosphorus Containing Quinazoline Compounds And Methods Of Use
View pageUS Patent:
20120196833, Aug 2, 2012
Filed:
Jul 2, 2010
Appl. No.:
13/380808
Inventors:
Wang Shen - San Mateo CA, US
Aimin Zhang - Castro Valley CA, US
Junfa Fan - Hayward CA, US
Xiaoling Zheng - Fremont CA, US
Aimin Zhang - Castro Valley CA, US
Junfa Fan - Hayward CA, US
Xiaoling Zheng - Fremont CA, US
International Classification:
A61K 31/675
A61P 35/00
C07F 9/6571
C07F 9/6584
C07F 9/655
A61P 35/00
C07F 9/6571
C07F 9/6584
C07F 9/655
US Classification:
514 80, 544244
Abstract:
Disclosed are novel quinazoline derivatives containing phosphorus substitutions and methods for the treatment of hyperproliferative diseases (e.g. cancer) using the compounds. These compounds are type I receptor protein kinase inhibitors useful in treating disorders related to abnormal protein kinase activities such as cancer and inflammation in mammals. Also disclosed are pharmaceutical compositions containing the compounds, methods for the preparation of the compounds and their pharmaceutically acceptable salts.
Substituted Anilines As Ccr(4) Antagonists
View pageUS Patent:
20130172315, Jul 4, 2013
Filed:
Nov 30, 2012
Appl. No.:
13/691571
Inventors:
Junfa Fan - Foster City CA, US
Christorpher W. Lange - El Cerrito CA, US
Manmohan Reddy Leleti - Cupertino CA, US
Yandong Li - San Jose CA, US
Venkat Reddy Mali - Cupertino CA, US
Jeffrey P. MacMahon - San Francisco CA, US
Jay Powers - Pacifica CA, US
Sreenivas Punna - Sunnyvale CA, US
Ju Yang - Palo Alto CA, US
Christorpher W. Lange - El Cerrito CA, US
Manmohan Reddy Leleti - Cupertino CA, US
Yandong Li - San Jose CA, US
Venkat Reddy Mali - Cupertino CA, US
Jeffrey P. MacMahon - San Francisco CA, US
Jay Powers - Pacifica CA, US
Sreenivas Punna - Sunnyvale CA, US
Ju Yang - Palo Alto CA, US
Assignee:
ChemoCentryx, Inc. - Mountain View CA
International Classification:
C07D 401/06
C07D 211/26
C07D 413/06
C07D 417/04
C07D 241/04
C07D 401/04
C07D 405/06
C07D 211/70
C07D 403/06
C07D 211/26
C07D 413/06
C07D 417/04
C07D 241/04
C07D 401/04
C07D 405/06
C07D 211/70
C07D 403/06
US Classification:
51421018, 546194, 514318, 546191, 514316, 546234, 514331, 544130, 5142355, 546208, 514326, 544365, 51425313, 544372, 51425401, 544393, 51425503, 544394, 544121, 5142358, 544374, 5142541, 540544, 51421115, 544 582, 5142278
Abstract:
Aniline compounds are provided which bind to CCR(4) and are useful for the treatment of diseases such as allergic diseases, autoimmune diseases, graft rejection and cancer.
Aza-Aryl 1H-Pyrazol-1-Yl Benzene Sulfonamides
View pageUS Patent:
20130225580, Aug 29, 2013
Filed:
Feb 28, 2013
Appl. No.:
13/781412
Inventors:
Junfa FAN - Foster City CA, US
Pingchen FAN - Fremont CA, US
Antoni KRASINSKI - San Jose CA, US
Lianfa LI - San Jose CA, US
Rebecca M. LUI - Santa Clara CA, US
Jeffrey P. McMAHON - San Francisco CA, US
Jay P. POWERS - Pacifica CA, US
Yibin ZENG - Foster City CA, US
Penglie ZHANG - Foster City CA, US
Pingchen FAN - Fremont CA, US
Antoni KRASINSKI - San Jose CA, US
Lianfa LI - San Jose CA, US
Rebecca M. LUI - Santa Clara CA, US
Jeffrey P. McMAHON - San Francisco CA, US
Jay P. POWERS - Pacifica CA, US
Yibin ZENG - Foster City CA, US
Penglie ZHANG - Foster City CA, US
Assignee:
CHEMOCENTRYX, INC. - Mountain View CA
International Classification:
C07D 405/14
A61K 31/4709
A61K 45/06
C07D 403/10
A61K 31/4725
C07D 231/42
A61K 31/415
A61K 31/502
A61K 31/5377
C07D 401/04
C07D 401/10
A61K 31/517
A61K 31/4709
A61K 45/06
C07D 403/10
A61K 31/4725
C07D 231/42
A61K 31/415
A61K 31/502
A61K 31/5377
C07D 401/04
C07D 401/10
A61K 31/517
US Classification:
5142352, 546167, 514314, 435375, 544284, 51426623, 5483721, 514407, 544237, 514248, 544128, 546162, 514313, 546143, 514310
Abstract:
Compounds are provided that act as potent antagonists of the CCR(9) receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR(9). The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR(9)-mediated diseases, and as controls in assays for the identification of CCR(9) antagonists.
Heteroaryl Btk Inhibitors
View pageUS Patent:
20120157442, Jun 21, 2012
Filed:
Sep 3, 2010
Appl. No.:
13/393191
Inventors:
Minna Bui - Oakland CA, US
Patrick Conlon - Wakefield MA, US
Daniel A. Erlanson - San Francisco CA, US
Junfa Fan - Foster City CA, US
Bing Guan - Needham MA, US
Brian T. Hopkins - Newton MA, US
Alexey Ishchenko - Somerville MA, US
Tracy J. Jenkins - Belmont MA, US
Gnanasambandam Kumaravel - Westford MA, US
Doug Marcotte - Worcester MA, US
Noel Powell - Westford MA, US
Daniel Scott - Weston MA, US
Art Taveras - Southborough MA, US
Deping Wang - Sharon MA, US
Min Zhong - Palo Alto CA, US
Patrick Conlon - Wakefield MA, US
Daniel A. Erlanson - San Francisco CA, US
Junfa Fan - Foster City CA, US
Bing Guan - Needham MA, US
Brian T. Hopkins - Newton MA, US
Alexey Ishchenko - Somerville MA, US
Tracy J. Jenkins - Belmont MA, US
Gnanasambandam Kumaravel - Westford MA, US
Doug Marcotte - Worcester MA, US
Noel Powell - Westford MA, US
Daniel Scott - Weston MA, US
Art Taveras - Southborough MA, US
Deping Wang - Sharon MA, US
Min Zhong - Palo Alto CA, US
Assignee:
SUNESIS PHARMACEUTICALS, INC. - South San Francisco CA
BIOGEN IDEC MA INC. - Weston MA
BIOGEN IDEC MA INC. - Weston MA
International Classification:
A61K 31/553
A61K 31/519
A61K 31/5377
C07D 401/04
A61K 31/506
A61P 35/02
A61K 31/55
C12N 9/99
A61P 37/06
A61P 29/00
A61P 35/00
C07D 487/04
C07D 471/04
A61K 31/519
A61K 31/5377
C07D 401/04
A61K 31/506
A61P 35/02
A61K 31/55
C12N 9/99
A61P 37/06
A61P 29/00
A61P 35/00
C07D 487/04
C07D 471/04
US Classification:
51421115, 544280, 5142651, 544117, 5142342, 544262, 5142621, 544329, 514256, 544279, 51426411, 51425216, 540600, 51421706, 544230, 540544, 435184
Abstract:
The present invention provides compounds useful as inhibitors of Btk, compositions thereof, and methods of using the same.
Bruton's Tyrosine Kinase Inhibitors
View pageUS Patent:
20120157443, Jun 21, 2012
Filed:
Sep 3, 2010
Appl. No.:
13/393192
Inventors:
Minna Bui - Oakland CA, US
Patrick Conlon - Wakefield MA, US
Julio H. Cuervo - Arlington MA, US
Daniel A. Erlanson - San Francisco CA, US
Junfa Fan - Foster City CA, US
Bing Guan - Needham MA, US
Brian T. Hopkins - Newton MA, US
Tracy J. Jenkins - Belmont MA, US
Gnanasambandam Kumaravel - Westford MA, US
Alexey A. Lugovskoy - Woburn MA, US
Doug Marcotte - Worcester MA, US
Noel Powell - Westford MA, US
Daniel Scott - Weston MA, US
Laura Silvian - Waban MA, US
Art Taveras - Southborough MA, US
Deping Wang - Sharon MA, US
Min Zhong - Palo Alto CA, US
Patrick Conlon - Wakefield MA, US
Julio H. Cuervo - Arlington MA, US
Daniel A. Erlanson - San Francisco CA, US
Junfa Fan - Foster City CA, US
Bing Guan - Needham MA, US
Brian T. Hopkins - Newton MA, US
Tracy J. Jenkins - Belmont MA, US
Gnanasambandam Kumaravel - Westford MA, US
Alexey A. Lugovskoy - Woburn MA, US
Doug Marcotte - Worcester MA, US
Noel Powell - Westford MA, US
Daniel Scott - Weston MA, US
Laura Silvian - Waban MA, US
Art Taveras - Southborough MA, US
Deping Wang - Sharon MA, US
Min Zhong - Palo Alto CA, US
Assignee:
SUNESIS PHARMACEUTICALS, INC. - South San Francisco CA
BIOGEN IDEC MA INC. - Weston MA
BIOGEN IDEC MA INC. - Weston MA
International Classification:
A61K 31/553
C07D 487/04
A61K 31/519
C07D 401/04
A61K 31/506
C07D 473/34
A61K 31/52
C07D 417/14
C07D 413/12
C07D 401/14
A61K 31/55
A61P 37/06
A61P 29/00
A61P 35/00
A61P 35/02
C12N 9/99
C07D 487/04
A61K 31/519
C07D 401/04
A61K 31/506
C07D 473/34
A61K 31/52
C07D 417/14
C07D 413/12
C07D 401/14
A61K 31/55
A61P 37/06
A61P 29/00
A61P 35/00
A61P 35/02
C12N 9/99
US Classification:
51421115, 435184, 544280, 5142651, 544262, 5142621, 544329, 514256, 544298, 514269, 544277, 51426322, 544327, 51425216, 540544, 540524, 51421208
Abstract:
The present invention provides compounds useful as inhibitors of Btk, compositions thereof, and methods of using the same.
Substituted Anilines As Ccr(4) Antagonists
View pageUS Patent:
20220194929, Jun 23, 2022
Filed:
Sep 9, 2021
Appl. No.:
17/470464
Inventors:
- San Carlos CA, US
Junfa FAN - Palo Alto CA, US
Christopher W. LANGE - Hayward CA, US
Manmohan Reddy LELETI - Dublin CA, US
Yandong LI - San Diego CA, US
Venkat Reddy MALI - Cupertino CA, US
Jeffrey P. McMAHON - San Francisco CA, US
Jay POWERS - Pacifica CA, US
Sreenivas PUNNA - Sunnyvale CA, US
Ju YANG - Palo Alto CA, US
Junfa FAN - Palo Alto CA, US
Christopher W. LANGE - Hayward CA, US
Manmohan Reddy LELETI - Dublin CA, US
Yandong LI - San Diego CA, US
Venkat Reddy MALI - Cupertino CA, US
Jeffrey P. McMAHON - San Francisco CA, US
Jay POWERS - Pacifica CA, US
Sreenivas PUNNA - Sunnyvale CA, US
Ju YANG - Palo Alto CA, US
International Classification:
C07D 413/06
C07D 401/04
C07D 403/06
C07D 405/06
C07D 417/04
C07D 211/56
C07D 295/135
C07D 211/62
C07D 401/06
C07D 211/26
C07D 211/70
C07D 241/04
C07D 207/16
C07D 211/34
A61K 31/451
A61K 31/454
A61K 31/4545
A61K 31/495
A61K 31/496
A61K 31/5377
C07D 401/04
C07D 403/06
C07D 405/06
C07D 417/04
C07D 211/56
C07D 295/135
C07D 211/62
C07D 401/06
C07D 211/26
C07D 211/70
C07D 241/04
C07D 207/16
C07D 211/34
A61K 31/451
A61K 31/454
A61K 31/4545
A61K 31/495
A61K 31/496
A61K 31/5377
Abstract:
Aniline compounds are provided which bind to CCR(4) and are useful for the treatment of diseases such as allergic diseases, autoimmune diseases, graft rejection and cancer.
Bruton's Tyrosine Kinase Inhibitors
View pageUS Patent:
20230046457, Feb 16, 2023
Filed:
May 12, 2022
Appl. No.:
17/743214
Inventors:
- Cardiff CA, US
- Cambridge MA, US
Julio H. CUERVO - Arlington MA, US
Daniel A. ERLANSON - San Francisco CA, US
Junfa FAN - Foster City CA, US
Bing GUAN - Needham MA, US
Brian T. HOPKINS - Newton MA, US
Tracy J. JENKINS - Watertown MA, US
Gnanasambandam KUMARAVEL - Westford MA, US
Alexey A. LUGOVSKOY - Woburn MA, US
Doug MARCOTTE - Worcester MA, US
Noel POWELL - Westford MA, US
Daniel SCOTT - Weston MA, US
Laura SILVIAN - Waban MA, US
Art TAVERAS - Southborough MA, US
Deping WANG - Sharon MA, US
Min ZHONG - Palo Alto CA, US
- Cambridge MA, US
Julio H. CUERVO - Arlington MA, US
Daniel A. ERLANSON - San Francisco CA, US
Junfa FAN - Foster City CA, US
Bing GUAN - Needham MA, US
Brian T. HOPKINS - Newton MA, US
Tracy J. JENKINS - Watertown MA, US
Gnanasambandam KUMARAVEL - Westford MA, US
Alexey A. LUGOVSKOY - Woburn MA, US
Doug MARCOTTE - Worcester MA, US
Noel POWELL - Westford MA, US
Daniel SCOTT - Weston MA, US
Laura SILVIAN - Waban MA, US
Art TAVERAS - Southborough MA, US
Deping WANG - Sharon MA, US
Min ZHONG - Palo Alto CA, US
International Classification:
C07D 487/14
C07D 401/04
C07D 401/14
C07D 413/14
C07D 417/14
C07D 471/04
C07D 473/34
C07D 487/04
C07D 401/04
C07D 401/14
C07D 413/14
C07D 417/14
C07D 471/04
C07D 473/34
C07D 487/04
Abstract:
The present invention provides compounds useful as inhibitors of Btk, compositions thereof, and methods of using the same.
Bruton's Tyrosine Kinase Inhibitors
View pageUS Patent:
20200399283, Dec 24, 2020
Filed:
Jan 21, 2020
Appl. No.:
16/748410
Inventors:
- South San Francisco CA, US
- Cambridge MA, US
Julio H. CUERVO - Arlington MA, US
Daniel A. ERLANSON - San Francisco CA, US
Junfa FAN - Foster City CA, US
Bing GUAN - Needham MA, US
Brian T. HOPKINS - Newton MA, US
Tracy J. JENKINS - Watertown MA, US
Gnanasambandam KUMARAVEL - Westford MA, US
Alexey A. LUGOVSKOY - Woburn MA, US
Doug MARCOTTE - Worcester MA, US
Noel POWELL - Westford MA, US
Daniel SCOTT - Weston MA, US
Laura SILVIAN - Waban MA, US
Art TAVERAS - Southborough MA, US
Deping WANG - Sharon MA, US
Min ZHONG - Palo Alto CA, US
- Cambridge MA, US
Julio H. CUERVO - Arlington MA, US
Daniel A. ERLANSON - San Francisco CA, US
Junfa FAN - Foster City CA, US
Bing GUAN - Needham MA, US
Brian T. HOPKINS - Newton MA, US
Tracy J. JENKINS - Watertown MA, US
Gnanasambandam KUMARAVEL - Westford MA, US
Alexey A. LUGOVSKOY - Woburn MA, US
Doug MARCOTTE - Worcester MA, US
Noel POWELL - Westford MA, US
Daniel SCOTT - Weston MA, US
Laura SILVIAN - Waban MA, US
Art TAVERAS - Southborough MA, US
Deping WANG - Sharon MA, US
Min ZHONG - Palo Alto CA, US
International Classification:
C07D 487/14
C07D 401/04
C07D 401/14
C07D 413/14
C07D 417/14
C07D 471/04
C07D 473/34
C07D 487/04
C07D 401/04
C07D 401/14
C07D 413/14
C07D 417/14
C07D 471/04
C07D 473/34
C07D 487/04
Abstract:
The present invention provides compounds useful as inhibitors of Btk, compositions thereof, and methods of using the same.