US Patent:
20120070410, Mar 22, 2012
Inventors:
Julius L. Apuy - San Diego CA, US
Darren E. Insko - San Diego CA, US
Joyce J. James - San Diego CA, US
International Classification:
A61K 31/429
A61P 35/02
A61P 29/00
A61P 37/06
A61P 25/28
A61P 3/10
A61P 1/00
A61P 31/00
A61K 31/5377
C07H 15/26
A61K 31/706
A61K 31/704
A61K 31/7068
A61K 31/664
A61K 31/573
A61K 31/7076
A61K 31/513
A61K 38/21
A61K 31/4745
A61K 31/553
A61K 31/498
A61K 31/517
A61K 31/496
C07D 513/04
US Classification:
424 854, 548151, 514366, 544133, 5142332, 536 174, 514 32, 514 34, 514 49, 514110, 514171, 514 48, 514274, 514283, 51421108, 514249, 51425217, 51425406
Abstract:
Compounds, compositions and methods are provided for modulating the activity of receptor kinases and for the treatment, prevention, or amelioration of one or more symptoms of disease or disorder mediated by receptor kinases.