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Jonathan Sprent

from La Jolla, CA
Age ~82
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Also known as:
Jonathan Prent
Phone and address:
10550 N Torrey Pines Rd, La Jolla, CA 92037
(760) 436-6687
Connected to:
Valoree R Sprentall, 72Paul R Spressart, 74Melissa A Spresser, 60Matthew D Sprester, 43Tom Sprester, 65Marco Spretke, 42Ruben Spretz, 57Kirby A Sprewell, 32Vickie M Sprewell, 62Curtis Sprewer, 46

Jonathan Sprent Phones & Addresses

  • 10550 N Torrey Pines Rd, La Jolla, CA 92037 (760) 436-6687
  • 10666 N Torrey Pines Rd, La Jolla, CA 92037
  • 1076 Hymettus Ave, Encinitas, CA 92024 (760) 436-6687
  • Leucadia, CA
  • San Diego, CA

Publications

Us Patents

Method For Producing A Synthetic Antigen Presenting Transformed Drosophila Cell

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US Patent:
6362001, Mar 26, 2002
Filed:
Mar 16, 1998
Appl. No.:
09/042492
Inventors:
Zeling Cai - San Diego CA
Jonathan Sprent - Leucadia CA
Anders Brunmark - San Diego CA
Michael Jackson - Del Mar CA
Per A. Peterson - Rancho Santa Fe CA
Assignee:
The Scripps Research Institute - La Jolla CA
International Classification:
C12N 1563
US Classification:
435465, 435455, 435348, 435325
Abstract:
Materials and methods of activating T lymphocytes with specificity for particular antigenic peptides are described, as well as the use of activated T lymphocytes in vitro for the treatment of a variety of disease conditions. In particular, a method for producing a synthetic antigen presenting drosophila cell line for activating T lymphocytes to a specific peptide is described.

Synthetic Antigen Presenting Matrix

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US Patent:
6461867, Oct 8, 2002
Filed:
Sep 8, 1997
Appl. No.:
08/913612
Inventors:
Zeling Cai - San Diego CA
Jonathan Sprent - Leucadia CA
Anders Brunmark - San Diego CA
Michael Jackson - Del Mar CA
Per A. Peterson - Rancho Santa Fe CA
Alain Luxembourg - La Jolla CA
Didier J. Leturcq - San Diego CA
Ann M. Moriarty - Poway CA
Assignee:
The Scripps Research Institute - La Jolla CA
International Classification:
C12N 506
US Classification:
435348, 435325, 435455, 530350
Abstract:
Materials and methods of activating T lymphocytes with specificity for particular antigenic peptides are described, as well as the use of activated T lymphocytes in vitro for the treatment of a variety of disease conditions. In particular, a synthetic antigen presenting matrix for activating T lymphocytes to a specific peptide is described.

Antigen Presenting System And Methods For Activation Of T-Cells

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US Patent:
6828150, Dec 7, 2004
Filed:
Oct 8, 2002
Appl. No.:
10/266463
Inventors:
Zeling Cai - San Diego CA
Jonathan Sprent - Leucadia CA
Anders Brunmark - San Diego CA
Michael Jackson - Del Mar CA
Per A. Peterson - Rancho Santa Fe CA
Alain Luxembourg - La Jolla CA
Didier J. Leturcq - San Diego CA
Ann M. Moriarty - Poway CA
Assignee:
The Scripps Research Institute - La Jolla CA
International Classification:
C12N 500
US Classification:
435377, 435348, 435325, 435455, 435383, 530350
Abstract:
The present invention relates to synthetic antigen-presenting matrices, their methods of making and their methods of use. One such matrix is cells that have been transfected to produce MHC antigen-presenting molecules and assisting molecules such as co-stimulatory molecules. The matrices can be used to activate CD8 T-cells to produce cytokines and become cytotoxic.

Synthetic Antigen Presenting Matrix With Liposome Support

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US Patent:
20030072796, Apr 17, 2003
Filed:
Mar 25, 2002
Appl. No.:
10/105200
Inventors:
Zeling Cai - San Diego CA, US
Jonathan Sprent - Leucadia CA, US
Anders Brunmark - San Diego CA, US
Michael Jackson - Del Mar CA, US
Per Peterson - Rancho Santa Fe CA, US
Assignee:
The Scripps Research Institute
International Classification:
A61K009/127
A61K038/17
C07K014/74
US Classification:
424/450000, 530/350000, 514/012000
Abstract:
Materials and methods for activating T lymphocytes with specificity for particular antigenic peptides are described, as well as the use of activated T lymphocytes in vitro for the treatment of a variety of disease conditions. In particular, a method for producing a synthetic antigen presenting cell line for activating T lymphocytes to a specific peptide is described.

Synthetic Antigen Presenting Matrix

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US Patent:
20030077318, Apr 24, 2003
Filed:
Mar 25, 2002
Appl. No.:
10/105504
Inventors:
Zeling Cai - San Diego CA, US
Jonathan Sprent - Leucadia CA, US
Anders Brunmark - San Diego CA, US
Michael Jackson - Del Mar CA, US
Per Peterson - Rancho Santa Fe CA, US
Assignee:
The Scripps Research Institute
International Classification:
A61K009/127
A61K038/17
C07K014/74
US Classification:
424/450000, 514/012000, 530/350000
Abstract:
Materials and methods for activating T lymphocytes with specificity for particular antigenic peptides are described, as well as the use of activated T lymphocytes in vitro for the treatment of a variety of disease conditions. In particular, a method for producing a synthetic antigen presenting cell line for activating T lymphocytes to a specific peptide is described.

Antigen Presenting System And Methods For Activation Of T-Cells

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US Patent:
20030077708, Apr 24, 2003
Filed:
Mar 25, 2002
Appl. No.:
10/105678
Inventors:
Zeling Cai - San Diego CA, US
Jonathan Sprent - Leucadia CA, US
Anders Brunmark - San Diego CA, US
Michael Jackson - Del Mar CA, US
Per Peterson - Rancho Santa Fe CA, US
Assignee:
The Scripps Research Institute
International Classification:
A61K048/00
C12P021/02
C12N005/06
C07K014/74
US Classification:
435/069100, 514/012000, 530/350000, 424/093210, 435/320100, 435/325000
Abstract:
Materials and methods for activating T lymphocytes with specificity for particular antigenic peptides are described, as well as the use of activated T lymphocytes in vitro for the treatment of a variety of disease conditions. In particular, a method for producing a synthetic antigen presenting cell line for activating T lymphocytes to a specific peptide is described.

Antigen Presenting System And Methods For Activation Of T-Cells

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US Patent:
20050152916, Jul 14, 2005
Filed:
Dec 7, 2004
Appl. No.:
11/005750
Inventors:
Zeling Cai - San Diego CA, US
Jonathan Sprent - Leucadia CA, US
Anders Brunmark - San Diego CA, US
Michael Jackson - Del Mar CA, US
Per Peterson - Rancho Santa Fe CA, US
Alain Luxembourg - La Jolla CA, US
Didier Leturcq - San Diego CA, US
Ann Moriarty - Poway CA, US
International Classification:
A61K039/00
C07K014/74
US Classification:
424185100, 530350000
Abstract:
The present invention relates to synthetic antigen-presenting matrices, their methods of making and their methods of use. One such matrix is cells that have been transfected to produce MHC antigen-presenting molecules and assisting molecules such as co-stimulatory molecules. The matrices can be used to activate CD8 T-cells to produce cytokines and become cytotoxic.

Antigen Presenting System And Methods For Activation Of T-Cells

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US Patent:
62250426, May 1, 2001
Filed:
Mar 16, 1998
Appl. No.:
9/039982
Inventors:
Zeling Cai - San Diego CA
Jonathan Sprent - Leucadia CA
Anders Brunmark - San Diego CA
Michael Jackson - Del Mar CA
Per A. Peterson - Rancho Santa Fe CA
Assignee:
The Scripps Research Institute - La Jolla CA
International Classification:
A01N 102
C12P 2106
C12N 510
C12N 1512
US Classification:
435 2
Abstract:
The present invention relates to methods for activating T lymphocytes using a synthetic matrix, and for specifically activating T lymphocytes reactive to a specific peptide.
Control profile
Jonathan Sprent from La Jolla, CA, age ~82 Get Report