Inventors:
Jorge A. Alvarado - Kentfield CA
Collin G. Murphy - Berkeley CA
Johnnie L. Hu - Portola Valley CA
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
A61K 3514
Abstract:
The treatment of glaucoma and other conditions relating to diseased trabecular meshwork in the eye is effected by administration of macrophages and/or cytokines to the eye. Increased levels of macrophages within the anterior chamber of the eye will at least partially clear obstruction of the trabecular meshwork and restore viability of trabecular cells in order to enhance release of aqueous fluid from the anterior chamber and reduce intraocular pressures. The administration of cytolines will either recruit macrophages or will effect repair of the trabecular meshwork cells directly.