Inventors:
Jessica Renee DesNoyer - San Jose CA, US
Stephen Dirk Pacetti - San Jose CA, US
Syed Faiyaz Shmed Hossainy - Fremont CA, US
Lothar Kleiner - Los Altos CA, US
Yiwen Tang - San Jose CA, US
Gina Zhang - Fremont CA, US
Assignee:
Advanced Cardiovascular Systems, Inc. - Santa Clara CA
International Classification:
A61K 31/00
A61L 31/10
A61L 27/34
A61L 29/08
C08G 63/02
US Classification:
424422, 424423, 514 1, 514 2, 525 542, 525 5421, 525 543, 525 5442, 525 58, 525 60, 525165, 525166, 525169, 525170, 525410, 525415, 525420, 525423, 525424, 525425, 525426, 525430, 623900, 423900
Abstract:
Provided herein is a PEA polymer blend and coatings or implantable devices formed therefrom. The PEA polymer blend is formed of a PEA polymer and a material capable of hydrogen bonding with the PEA. The PEA polymer blend can form a coating on an implantable device, one example of which is a stent. The coating can optionally include a biobeneficial material and/or optionally with a bioactive agent. The implantable device can be used to treat or prevent a disorder such as one of atherosclerosis, thrombosis, restenosis, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, and combinations thereof.