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Jeffrey Barminko Phones & Addresses

  • East Brunswick, NJ
  • Highland Park, NJ
  • 21 North St, Old Bridge, NJ 08857 (732) 501-6145
  • New York, NY

Publications

Us Patents

Therapeutic Encapsulated Embryonic Stem Cells And Mesenchymal Stromal Cells

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US Patent:
20120020931, Jan 26, 2012
Filed:
Jun 2, 2011
Appl. No.:
13/151912
Inventors:
Martin L. Yarmush - Newton MA, US
Rene S. Schloss - East Brunswick NJ, US
Martin Grumet - New York NY, US
Jeffrey Barminko - Old Bridge NJ, US
Jae Hwan Kim - Highland Park NJ, US
Tim Maguire - Piscataway NJ, US
Jean-Pierre Dolle - Metuchen NJ, US
Lulu Li - New Brunswick NJ, US
Assignee:
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY - New Brunswick NJ
International Classification:
C12N 11/10
A61P 25/00
A61K 35/12
US Classification:
424 937, 435178
Abstract:
This application discloses alginate microencapsulation-mediated differentiation of embryonic stem cells and use of the stem cell differentiation method for the development of effective treatment of various diseases and disorders. The microencapsulation of embryonic stem (ES) cells results in decreased cell aggregation and enhanced neural lineage differentiation through incorporating the soluble inducer retinoic acid (RA) into the permeable microcapsule system. This application also discloses a micro-encapsulation system for immobilizing mesenchymal stromal cells (MSCs) while sustaining the molecular communication. Thus, the invention provides the use of encapsulated mesenchymal stromal cells in the cellular transplantation therapies. Moreover, the invention provides methods for delivery of encapsulated MSCs into the central nervous system and therapies derived therefrom, such as, the treatment of spinal cord injury (SCI) and other inflammatory conditions.

Therapeutic Encapsulated Mesenchymal Stromal Cells

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US Patent:
20170100435, Apr 13, 2017
Filed:
Oct 20, 2016
Appl. No.:
15/298271
Inventors:
- New Brunswick NJ, US
Martin L. Yarmush - Newton MA, US
Rene S. Schloss - East Brunswick NJ, US
Jeffrey Barminko - Old Bridge NJ, US
Assignee:
Rutgers, The State University of New Jersey - New Brunswick NJ
International Classification:
A61K 35/28
A61K 9/48
Abstract:
This application discloses a micro-encapsulation system for immobilizing mesenchymal stromal cells (MSCs) while sustaining the molecular communication. Thus, the invention provides the use of encapsulated mesenchymal stromal cells in the cellular transplantation therapies. Moreover, the invention provides methods for delivery of encapsulated MSCs into the central nervous system and therapies derived therefrom, such as, the treatment of spinal cord injury (SCI) and other inflammatory conditions.
Jeffrey A Barminko from East Brunswick, NJ, age ~39 Get Report