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Jean S Kahan

from Medford, NJ
Age ~83
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Also known as:
Jean Sawyer Kahan
Phone and address:
657 Medford Leas, Medford, NJ 08055
(908) 233-7118
Related to:
Frederick Marvion Kahan, 90Fred M Kahan, 89
Connected to:
Alex Kahan, 90Avi Kahan, 35Helene R Kahan, 75Joanne Kahan, 62Leiba L Kahan, 60Liz Kahan, 89Matthew Kahan, 35Michael L Kahan, 55Norma Kahan, 66Robin F Kahan, 65

Jean Kahan Phones & Addresses

  • 657 Medford Leas, Medford, NJ 08055 (908) 233-7118
  • Rahway, NJ
  • Scotch Plains, NJ
  • Long Beach, CA
  • 2022 Brookside Dr, Scotch Plains, NJ 07076

Publications

Us Patents

Thienamycin Production

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US Patent:
40060608, Feb 1, 1977
Filed:
Nov 18, 1975
Appl. No.:
5/632938
Inventors:
Jean S. Kahan - Rahway NJ
Frederick M. Kahan - Rahway NJ
Edward O. Stapley - Metuchen NJ
Robert T. Goegelman - Linden NJ
Sebastian Hernandez - Madrid, ES
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
C12D 914
US Classification:
195 80R
Abstract:
The antibiotic thienamycin is active against both gram-positive and gram-negative bacteria. The antibiotic is produced by growing a newly-found and hitherto undescribed species of Streptomyces on suitable fermentation media.

Antibiotics

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US Patent:
40815480, Mar 28, 1978
Filed:
Sep 3, 1976
Appl. No.:
5/720483
Inventors:
Jean S. Kahan - Rahway NJ
Frederick M. Kahan - Rahway NJ
Edward O. Stapley - Metuchen NJ
Robert T. Goegelman - Linden NJ
Sebastian Hernandez - Madrid, ES
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
A61K 3140
US Classification:
424274
Abstract:
The antibiotic thienamycin is active against both gram-positive and gram-negative bacteria. The antibiotic is produced by growing a newly-found and hitherto undescribed species of Streptomyces on suitable fermentation media.

Antibiotics

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US Patent:
39503577, Apr 13, 1976
Filed:
Nov 25, 1974
Appl. No.:
5/526992
Inventors:
Jean S. Kahan - Rahway NJ
Frederick M. Kahan - Rahway NJ
Edward O. Stapley - Metuchen NJ
Robert T. Goegelman - Linden NJ
Sebastian Hernandez - Madrid, ES
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
C07D20712
US Classification:
26032627
Abstract:
The antibiotic thienamycin is active against both gram-positive and gram-negative bacteria. The antibiotic is produced by growing a newly-found and hitherto undescribed species of Streptomyces on suitable fermentation media.

Culture Of Streptomyces Cattleya

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US Patent:
43048676, Dec 8, 1981
Filed:
Jan 3, 1978
Appl. No.:
5/866574
Inventors:
Jean S. Kahan - Rahway NJ
Frederick M. Kahan - Rahway NJ
Edward O. Stapley - Metuchen NJ
Robert T. Goegelman - Linden NJ
Sebastian Hernandez - Madrid, ES
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
C12N 120
US Classification:
435253
Abstract:
The antibiotic thienamycin is active against both gram-positive and gram-negative bacteria. The antibiotic is produced by growing a newly-found and hitherto undescribed species of Streptomyces on suitable fermentation media.

Process For Deacylating N-Acyl-6-Substituted-2-[2-Aminoethylthio]-1-Carbadethiapen-2-Em-3-Carbox Ylic Acids

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US Patent:
42073952, Jun 10, 1980
Filed:
Nov 2, 1978
Appl. No.:
5/956951
Inventors:
Patrick J. Cassidy - Rahway NJ
Jean S. Kahan - Rahway NJ
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
C12P 1718
US Classification:
435119
Abstract:
Disclosed is a process for enzymatically cleaving the acyl group from N-acyl-6-substituted-2-substituted-1-carbadethiapen-2-em-3-carboxylic acids. The acylated substrate and the deacylated product are antibiotics.

Enzymatic Cleavage Of N-Acyl-Thienamycins

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US Patent:
41621930, Jul 24, 1979
Filed:
Aug 19, 1977
Appl. No.:
5/825883
Inventors:
Jean S. Kahan - Rahway NJ
Frederick M. Kahan - Rahway NJ
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
C12D 1306
US Classification:
43121
Abstract:
A method is disclosed for cleaving N-acyl-thienamycin compounds to yield thienamycin. The new method disclosed herein utilizes enzymes which are penicillin amidohydrolases to treat the starting compounds resulting in the antibiotic thienamycin.

Process For Producing Antibiotic Desacetyl 890A.sub.10

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US Patent:
42647347, Apr 28, 1981
Filed:
Sep 11, 1979
Appl. No.:
6/074289
Inventors:
Jean S. Kahan - Rahway NJ
Frederick M. Kahan - Rahway NJ
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
C12P 1718
US Classification:
435119
Abstract:
This invention relates to the new antibiotic, desacetyl 890A. sub. 10, active against both gram-positive and gram-negative bacteria, which is produced by treating 890A. sub. 10 with an N-acetyl-890A. sub. 10 amidohydrolase produced by a soil microorganism isolated by enrichment techniques. This invention also relates to the process by which 890A. sub. 10 is enzymatically deacetylated.

Acetylthienamycin Production

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US Patent:
42295343, Oct 21, 1980
Filed:
Apr 5, 1979
Appl. No.:
6/027531
Inventors:
Jean S. Kahan - Rahway NJ
Frederick M. Kahan - Rahway NJ
Robert T. Goegelman - Linden NJ
Edward O. Stapley - Metuchen NJ
Sebastian Hernandez - Madrid, ES
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
C12P 1718
US Classification:
435119
Abstract:
The antibiotic N-acetyl thienamycin and its non-toxic pharmaceutically acceptable salts are active against both gram-positive and gram-negative bacteria. The antiobiotic is produced by growing a species of Streptomyces on suitable fermentation media or alternatively by acetylation of thienamycin.
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Jean S Kahan from Medford, NJ, age ~83 Get Report