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Jay W Hooper

from New Market, MD
Age ~61

Jay Hooper Phones & Addresses

  • 6522 Twin Lake Dr, New Market, MD 21774 (301) 865-2073
  • 12903 Churchill Ridge Cir, Germantown, MD 20874
  • Frederick, MD
  • Hyde Park, MA
  • Annapolis, MD

Business Records

Name / Title
Company / Classification
Phones & Addresses
Jay Hooper
Manager
TAURUS CORPORATE PROPERTIES, LLC
22 Batterymarch St, Boston, MA 02109
Jay Hooper
Chief
BioFactura, Inc.
Biotechnology · Commercial Medical Research Srvcs
9430 Ky West Ave SUITE 125, Rockville, MD 20850
(301) 315-8002

Publications

Isbn (Books And Publications)

Introduction to Plcs

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Author

Jay F. Hooper

ISBN #

0890891192

Introduction to Plcs

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Author

Jay F. Hooper

ISBN #

0890893896

Us Patents

Dna Vaccines Against Poxviruses

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US Patent:
6562376, May 13, 2003
Filed:
Mar 7, 2001
Appl. No.:
09/800632
Inventors:
Jay W. Hooper - New Market MD
Alan L. Schmaljohn - Frederick MD
Connie S. Schmaljohn - Frederick MD
Assignee:
The United States of America as represented by the Secretary of the Army - Washington DC
International Classification:
A61K 914
US Classification:
424489, 4241991, 514 44, 435459, 4353201, 4352351
Abstract:
In this application is described a poxvirus naked DNA vaccine which protects animals against poxvirus challenge comprising IMV and EEV nucleic acids from poxvirus. Methods of use of the vaccine and its advantages are described.

Prophylactic And Therapeutic Monoclonal Antibodies

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US Patent:
6620412, Sep 16, 2003
Filed:
Sep 16, 2002
Appl. No.:
10/202532
Inventors:
Jay W. Hooper - New Market MD
Alan L. Schmaljohn - Frederick MD
Connie S. Schmaljohn - Frederick MD
Assignee:
The United States of America as represented by the Secretary of the Army - Washington DC
International Classification:
A61K 3942
US Classification:
4241471, 4242321, 5303883
Abstract:
In this application are described vaccinia monoclonal antibodies. Also provided are mixtures of antibodies of the present invention, as well as methods of using individual antibodies or mixtures thereof for the detection, prevention, and/or therapeutical treatment of vaccinia virus infections in vitro and in vivo.

Extraneous Dna Sequence That Facilitates Hantavirus Gene Expression

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US Patent:
7217812, May 15, 2007
Filed:
Mar 21, 2003
Appl. No.:
10/394388
Inventors:
Jay W. Hooper - New Market MD, US
Connie S. Schmaljohn - Frederick MD, US
Max Custer - Durham NC, US
Assignee:
United States of America as represented by the Secretary of the Army - Washington DC
International Classification:
C07H 21/04
US Classification:
536 241, 536 2372, 4242041
Abstract:
In this application is described a protective DNA vaccines against infection with HFRS- and HPS-associated hantaviruses. The vaccines were constructed by subcloning cDNA representing the medium (M) (encoding the G1 and G2 glycoproteins) into the DNA expression vector pWRG7077. Animals vaccinated with the M construct developed a neutralizing antibody response. Passive transfer experiments show that serum from vaccinated animals, when injected on days 4 or 5 after challenge, protected animals from lethal disease.

Protein Vaccines Against Poxviruses

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US Patent:
7790182, Sep 7, 2010
Filed:
Sep 20, 2006
Appl. No.:
11/523867
Inventors:
Jay W. Hooper - New Market MD, US
Genoveffa Franchini - Washington DC, US
Assignee:
The United States of America as represented by the Secretary of the Army - Washington DC
International Classification:
A61K 39/275
A61K 39/285
A61K 31/7088
US Classification:
4242321, 514 44 R
Abstract:
The invention described here entails a protein vaccine against poxviruses which contains at least two purified recombinant monkeypox virus proteins or peptides. The proteins or peptides are encoded by the open reading frames of the monkeypox ortholog genes M1R, A35R, A29L B6R, and orthologs of these proteins or peptides having 90% identity. The invention also entails a vaccine protocol against poxvirus whereby a vaccine is vaccinated with a first vaccine made up of a nucleic acid vaccine of three or more poxvirus virus genes, and subsequently vaccinated with at least one other booster vaccine made up of two or more poxvirus virus proteins.

Puumala Virus Full-Length M Segment-Based Dna Vaccines

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US Patent:
8183358, May 22, 2012
Filed:
Feb 12, 2008
Appl. No.:
12/449504
Inventors:
Jay Hooper - New Market MD, US
Assignee:
The United States of America, as represented by the Secretary of the Army - Washington DC
International Classification:
A61K 39/12
C12N 15/00
US Classification:
536 2372, 4241861, 4353201
Abstract:
The invention contemplates a new synthetic, codon-optimized Puumala virus (PUUV) full-length M gene open reading frame (ORF) that encodes a unique consensus amino acid sequence. The PUUV ORF was cloned into a plasmid to form the first stable PUUV full-length M gene that elicits neutralizing antibodies. The gene can be engineered into a molecular vaccine system, and is useful to protect mammals against infection with Puumala virus.

Dna Immunogenic Composition Comprising A Full-Length Modified Poxvirus L1R Gene Fused To A Tpa Leader Sequence

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US Patent:
8513005, Aug 20, 2013
Filed:
Jul 7, 2008
Appl. No.:
12/217584
Inventors:
Jay W. Hooper - New Market MD, US
Joseph W. Golden - Hagerstown MD, US
Assignee:
The United States of America as Represented by the Secretary of the Army - Washington DC
International Classification:
C12N 15/00
US Classification:
4353201, 435455
Abstract:
The invention described here encompasses DNA and protein vaccines against poxviruses, and relevant immunogenic compositions, comprising at a minimum a nucleic acid encoding a modified full-length poxvirus L1R gene or its ortholog. The L1R gene is modified so that an endoplasmic reticulum-targeting sequence is operably linked on the 5′ end. Preferably the nucleic acid sequences for other poxviruses antigens are also included, such as A33R, B5R and/or A27L. These vaccines and compositions provide improved neutralizing antibody response elicited by molecular poxvirus vaccines, over known vaccines using unmodified L1R.

Prophylactic And Therapeutic Monoclonal Antibodies

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US Patent:
20020009447, Jan 24, 2002
Filed:
Feb 9, 2001
Appl. No.:
09/781124
Inventors:
Jay Hooper - New Market MD, US
Alan Schmaljohn - Frederick MD, US
Connie Schmaljohn - Frederick MD, US
International Classification:
A61K039/42
C07K016/00
C12P021/08
US Classification:
424/147100, 530/388300
Abstract:
In this application are described vaccinia monoclonal antibodies. Also provided are mixtures of antibodies of the present invention, as well as methods of using individual antibodies or mixtures thereof for the detection, prevention, and/or therapeutical treatment of vaccinia virus infections in vitro and in vivo.

Protein Vaccines Against Poxviruses

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US Patent:
20110081368, Apr 7, 2011
Filed:
May 28, 2010
Appl. No.:
12/802034
Inventors:
Jay W. Hooper - New Market MD, US
Genoveffa Franchini - Washington DC, US
International Classification:
A61K 39/275
A61K 39/285
A61P 31/20
US Classification:
4241861, 4242321
Abstract:
The invention described here entails a protein vaccine against poxviruses which contains at least two purified recombinant monkeypox virus proteins or peptides. The proteins or peptides are encoded by the open reading frames of the monkeypox ortholog genes M1R, A35R, A29L B6R, and orthologs of these proteins or peptides having 90% identity. The invention also entails a vaccine protocol against poxvirus whereby a vaccine is vaccinated with a first vaccine made up of a nucleic acid vaccine of three or more poxvirus virus genes, and subsequently vaccinated with at least one other booster vaccine made up of two or more poxvirus virus proteins.

Wikipedia References

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Jay Hooper

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Jay Hooper (Politician)

Jay W Hooper from New Market, MD, age ~61 Get Report