Search

Jason D Buenrostro

from Belmont, MA
Age ~36
Get Report
Related to:
Renee Elizabeth Bontempi, 65Martin Buenrostro, 33Irma BuenrostroBertha Buenrostro, 51Israel Caravez, 72Irma Buenrostro, 54
Connected to:
Abraham Buenrostro, 29Alba Buenrostro, 37Aldo U Buenrostro, 38Dana Buenrostro, 40Elena Buenrostro, 49Federico Buenrostro, 75Julian Buenrostro, 54Leonel Buenrostro, 61Liliana I Buenrostro, 47Lucy Buenrostro, 73

Jason Buenrostro Phones & Addresses

  • Belmont, MA
  • 3523 Altamont Way, Redwood City, CA 94062 (650) 722-1081
  • Cambridge, MA
  • Santa Clara, CA

Work

Company: Stanford university school of medicine Jun 2011 Position: Phd student

Education

Degree: Doctor of Philosophy (PhD) School / High School: Stanford University School of Medicine 2011 to 2016 Specialities: Genetics

Skills

Molecular Biology • Genomics • Genetics • Bioinformatics • Dna Sequencing • Sequencing • High Throughput Screening • Pcr • Life Sciences • Fluorescence Microscopy • Cell Biology • Cancer • Lifesciences • Cell • Polymerase Chain Reaction • Technology Development • Personalized Medicine

Languages

English • Spanish

Industries

Biotechnology

Resumes

Resumes

Jason Buenrostro Photo 1

Assistant Professor

View page
Location:
Palo Alto, CA
Industry:
Biotechnology
Work:
Stanford University School of Medicine since Jun 2011
PhD student
Stanford University School of Medicine Jun 2009 - Jun 2011
Research Assistant
Santa Clara University 2007 - 2009
Research Assistant
Education:
Stanford University School of Medicine 2011 - 2016
Doctor of Philosophy (PhD), Genetics Santa Clara University 2005 - 2009
Bachelor of Science, Biology Santa Clara University 2005 - 2009
Bachelor of Science, Bioengineering Woodside Priory 2001 - 2005
Skills:
Molecular Biology
Genomics
Genetics
Bioinformatics
Dna Sequencing
Sequencing
High Throughput Screening
Pcr
Life Sciences
Fluorescence Microscopy
Cell Biology
Cancer
Lifesciences
Cell
Polymerase Chain Reaction
Technology Development
Personalized Medicine
Languages:
English
Spanish

Publications

Us Patents

Direct Capture, Amplification And Sequencing Of Target Dna Using Immobilized Primers

View page
US Patent:
20120157322, Jun 21, 2012
Filed:
Sep 21, 2011
Appl. No.:
13/239226
Inventors:
Samuel Myllykangas - Espoo, FI
Jason Buenrostro - Redwood City CA, US
Hanlee P. Ji - Stanford CA, US
International Classification:
C40B 20/00
C40B 40/06
C12P 19/34
US Classification:
506 2, 435 912, 506 16
Abstract:
Certain embodiments provide a method for capturing a genomic fragment. The method may comprise: obtaining a substrate comprising a first population of surface-bound oligonucleotides and a second population of surface-bound oligonucleotides; hybridizing a first member of the first population of surface-bound oligonucleotides to a selection oligonucleotide comprising a region that hybridizes with the first member and a region that contains a genomic sequence; extending the first member of the first population of surface-bound oligonucleotides to produce a support-bound selection primer that comprises a sequence that is complementary to the genomic sequence; hybridizing the support-bound selection primer to a nucleic acid fragment comprising the genomic sequence; extending the support-bound selection primer to produce an extension product that contains a sequence that flanks the genomic sequence, e.g., in a genome; and amplifying the extension product on the substrate.

Transposition Of Native Chromatin For Personal Epigenomics

View page
US Patent:
20220325342, Oct 13, 2022
Filed:
Jun 6, 2022
Appl. No.:
17/833686
Inventors:
- Stanford CA, US
Jason D. Buenrostro - Redwood City CA, US
Howard Y. Chang - Stanford CA, US
William J. Greenleaf - Menlo Park CA, US
International Classification:
C12Q 1/6874
C12Q 1/6869
G16B 30/00
C12Q 1/6806
G16H 50/20
G16B 20/00
Abstract:
Provided herein is a method for analyzing polynucleotides such as genomic DNA. In certain embodiments, the method comprises: (a) treating chromatin isolated from a population of cells with an insertional enzyme complex to produce tagged fragments of genomic DNA; (b) sequencing a portion of the tagged fragments to produce a plurality of sequence reads; and (c) making an epigenetic map of a region of the genome of the cells by mapping information obtained from the sequence reads to the region. A kit for performing the method is also provided.

Transposition Of Native Chromatin For Personal Epigenomics

View page
US Patent:
20210285045, Sep 16, 2021
Filed:
Dec 7, 2020
Appl. No.:
17/114278
Inventors:
- Stanford CA, US
Jason D. Buenrostro - Redwood City CA, US
Howard Y. Chang - Stanford CA, US
William J. Greenleaf - Menlo Park CA, US
International Classification:
C12Q 1/6874
C12Q 1/6869
G16B 30/00
C12Q 1/6806
G16H 50/20
G16B 20/00
Abstract:
Provided herein is a method for analyzing polynucleotides such as genomic DNA. In certain embodiments, the method comprises: (a) treating chromatin isolated from a population of cells with an insertional enzyme complex to produce tagged fragments of genomic DNA; (b) sequencing a portion of the tagged fragments to produce a plurality of sequence reads; and (c) making an epigenetic map of a region of the genome of the cells by mapping information obtained from the sequence reads to the region. A kit for performing the method is also provided.

Lineage Tracing Using Mitochondrial Genome Mutations And Single Cell Genomics

View page
US Patent:
20210246503, Aug 12, 2021
Filed:
Jun 11, 2019
Appl. No.:
17/251451
Inventors:
- Cambridge MA, US
- Boston MA, US
Vijay G. Sankaran - Boston MA, US
Jason Buenrostro - Cambridge MA, US
Christoph Muus - Cambridge MA, US
International Classification:
C12Q 1/6869
C12Q 1/6827
A61K 45/06
C12Q 1/6886
Abstract:
Embodiments disclosed herein provide methods of using somatic mutations in mitochondrial genomes to retrospectively infer cell lineages in native contexts and to serve as genetic barcodes to measure clonal dynamics in complex cellular populations. Further, somatic mutations in mitochondrial DNA (mtDNA) are tracked by single cell genomic approaches for simultaneous analysis of single cell lineage and state. Applicants further show that mitochondrial mutations can be readily detected with contemporary single cell transcriptomic and epigenomic technologies to concomitantly capture gene expression profiles and chromatin accessibility, respectively.

Transposition Of Native Chromatin For Personal Epigenomics

View page
US Patent:
20200332359, Oct 22, 2020
Filed:
Jul 1, 2020
Appl. No.:
16/918924
Inventors:
- Stanford CA, US
Jason D. Buenrostro - Redwood City CA, US
Howard Y. Chang - Stanford CA, US
William J. Greenleaf - Menlo Park CA, US
International Classification:
C12Q 1/6874
C12Q 1/6869
G16B 30/00
C12Q 1/6806
G16H 50/20
G16B 20/00
Abstract:
Provided herein is a method for analyzing polynucleotides such as genomic DNA. In certain embodiments, the method comprises: (a) treating chromatin isolated from a population of cells with an insertional enzyme complex to produce tagged fragments of genomic DNA; (b) sequencing a portion of the tagged fragments to produce a plurality of sequence reads; and (c) making an epigenetic map of a region of the genome of the cells by mapping information obtained from the sequence reads to the region. A kit for performing the method is also provided.

Enrichment Of Dna Sequencing Libraries From Samples Containing Small Amounts Of Target Dna

View page
US Patent:
20200139335, May 7, 2020
Filed:
Jan 15, 2020
Appl. No.:
16/743501
Inventors:
- Stanford CA, US
Meredith L. Carpenter - San Mateo CA, US
Jason D. Buenrostro - Redwood City CA, US
William J. Greenleaf - Menlo Park CA, US
International Classification:
B01J 19/00
C12Q 1/6806
C12N 15/10
C12Q 1/6809
Abstract:
Provided herein is a method for capturing DNA molecules in solution. The method may comprise: extracting DNA from a sample that comprises endogenous DNA and environmental DNA to produce extracted DNA; ligating universal adaptors to the extracted DNA; hybridizing the extracted DNA, in solution, with affinity-tagged RNA probes generated by: in vitro transcribing a library of fragmented reference genomic DNA that has been ligated to an RNA promoter adaptor, in the presence of an affinity-tagged ribonucleotide; binding the product with a capture agent that is tethered to a substrate in the presence of RNA oligonucleotides that are complementary to the adaptors, thereby capturing the hybridized DNA molecules on the substrate; washing the substrate to remove any unbound DNA molecules; and releasing the captured DNA molecules. A kit for performing the method is also provided.

Transposition Of Native Chromatin For Personal Epigenomics

View page
US Patent:
20190316196, Oct 17, 2019
Filed:
May 21, 2019
Appl. No.:
16/418796
Inventors:
- Stanford CA, US
Jason D. Buenrostro - Redwood City CA, US
Howard Y. Chang - Stanford CA, US
William J. Greenleaf - Menlo Park CA, US
International Classification:
C12Q 1/6874
C12Q 1/6806
C12Q 1/6869
Abstract:
Provided herein is a method for analyzing polynucleotides such as genomic DNA. In certain embodiments, the method comprises: (a) treating chromatin isolated from a population of cells with an insertional enzyme complex to produce tagged fragments of genomic DNA; (b) sequencing a portion of the tagged fragments to produce a plurality of sequence reads; and (c) making an epigenetic map of a region of the genome of the cells by mapping information obtained from the sequence reads to the region. A kit for performing the method is also provided.

Transposition Of Native Chromatin For Personal Epigenomics

View page
US Patent:
20190309362, Oct 10, 2019
Filed:
May 21, 2019
Appl. No.:
16/418889
Inventors:
- Stanford CA, US
Jason D. Buenrostro - Redwood City CA, US
Howard Y. Chang - Stanford CA, US
William J. Greenleaf - Menlo Park CA, US
International Classification:
C12Q 1/6874
C12Q 1/6806
C12Q 1/6869
Abstract:
Provided herein is a method for analyzing polynucleotides such as genomic DNA. In certain embodiments, the method comprises: (a) treating chromatin isolated from a population of cells with an insertional enzyme complex to produce tagged fragments of genomic DNA; (b) sequencing a portion of the tagged fragments to produce a plurality of sequence reads; and (c) making an epigenetic map of a region of the genome of the cells by mapping information obtained from the sequence reads to the region. A kit for performing the method is also provided.
Control profile
Jason D Buenrostro from Belmont, MA, age ~36 Get Report