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Jared A Iacovelli

from San Diego, CA
Age ~47
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Also known as:
Jared Adam Iacovelli, Jared A Lacovelli, Jared T
Related to:
Gail Iacovelli
Connected to:
Alexa E Iacovelli, 35Gloria Iacovella, 61Jason C Iacovelli, 49Peter T Iacovelli, 68Renald C Iacovelli, 98Shaun H Iacovelli, 43Billi J Iacovetta, 69Chad Iacovetta, 41Glenn T Iacovetta, 65Lisa Iacovetti, 52

Jared Iacovelli Phones & Addresses

  • San Diego, CA
  • 20 Rich St #2, Waltham, MA 02451 (215) 765-1832
  • Cambridge, MA
  • 838 Newkirk St, Philadelphia, PA 19130 (215) 765-1832
  • 838 N Newkirk St APT F1, Philadelphia, PA 19130
  • Apalachin, NY
  • Ithaca, NY
  • Scottsdale, AZ
  • Celebration, FL

Publications

Us Patents

Messenger Ribonucleic Acids For Enhancing Immune Responses And Methods Of Use Thereof

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US Patent:
20200261572, Aug 20, 2020
Filed:
Nov 1, 2019
Appl. No.:
16/671921
Inventors:
- Cambridge MA, US
Jared IACOVELLI - Waltham MA, US
Kristine MCKINNEY - Cambridge MA, US
Kristen HOPSON - Arlington MA, US
International Classification:
A61K 39/39
A61K 31/7088
A61P 35/00
A61K 39/00
A61K 39/02
C12N 7/00
A61K 39/12
C07K 14/47
A61K 9/51
Abstract:
The disclosure features isolated mRNAs encoding a polypeptide that enhances immune responses to an antigen(s) of interest, such as polypeptides that activate Type I interferon pathway signaling or NFkB signaling, including mRNAs comprising one or more modified nucleobase. The disclosure also features methods of using the same, for example, for enhancing immune responses when administered with an antigen(s) of interest, such as to stimulate anti-cancer immune responses or anti-pathogen immune responses.

Immunomodulatory Therapeutic Mrna Compositions Encoding Activating Oncogene Mutation Peptides

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US Patent:
20190351039, Nov 21, 2019
Filed:
Feb 1, 2018
Appl. No.:
16/482473
Inventors:
- Cambridge MA, US
Jared IACOVELLI - Waltham MA, US
Kristine MCKINNEY - Cambridge MA, US
Nicholas VALIANTE - Cambridge MA, US
International Classification:
A61K 39/00
A61K 9/50
A61K 39/39
A61K 9/51
A61K 9/00
Abstract:
The disclosure features immunomodulatory therapeutic compositions of an mRNA encoding an activating oncogene mutation peptide and an mRNA encoding a polypeptide that enhances immune responses to the activating oncogene mutation peptide, for example an mRNA encoding an immune potentiator. The disclosure also features methods of using the same, for example, to stimulate anti-cancer immune responses.

Immunomodulatory Therapeutic Mrna Compositions Encoding Activating Oncogene Mutation Peptides

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US Patent:
20190175727, Jun 13, 2019
Filed:
Feb 19, 2019
Appl. No.:
16/279372
Inventors:
- Cambridge MA, US
Jared IACOVELLI - Waltham MA, US
Kristine MCKINNEY - Cambridge MA, US
Nicholas VALIANTE - Cambridge MA, US
International Classification:
A61K 39/39
C07K 14/725
A61K 9/50
A61P 35/00
Abstract:
The disclosure features immunomodulatory therapeutic compositions of an mRNA encoding an activating oncogene mutation peptide and an mRNA encoding a polypeptide that enhances immune responses to the activating oncogene mutation peptide, for example an mRNA encoding an immune potentiator. The disclosure also features methods of using the same, for example, to stimulate anti-cancer immune responses.

Messenger Ribonucleic Acids For Enhancing Immune Responses And Methods Of Use Thereof

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US Patent:
20180311343, Nov 1, 2018
Filed:
Jun 1, 2018
Appl. No.:
15/995519
Inventors:
- Cambridge MA, US
Jared IACOVELLI - Waltham MA, US
Kristine MCKINNEY - Cambridge MA, US
Kristen HOPSON - Arlington MA, US
International Classification:
A61K 39/39
A61P 35/00
A61K 39/00
A61K 9/51
C07K 14/47
A61K 39/12
C12N 7/00
A61K 39/02
Abstract:
The disclosure features isolated mRNAs encoding a polypeptide that enhances immune responses to an antigen(s) of interest, such as polypeptides that activate Type I interferon pathway signaling or NFkB signaling, including mRNAs comprising one or more modified nucleobase. The disclosure also features methods of using the same, for example, for enhancing immune responses when administered with an antigen(s) of interest, such as to stimulate anti-cancer immune responses or anti-pathogen immune responses.
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Jared A Iacovelli from San Diego, CA, age ~47 Get Report