Inventors:
- Seattle WA, US
Kristin M. Bedard - Seattle WA, US
Kerry W. Fowler - Seattle WA, US
Ikenna Madu - Seattle WA, US
Shari Kaiser - Seattle WA, US
Assignee:
Kineta, Inc. - Seattle WA
International Classification:
C07D 513/04
C07D 417/12
C07D 277/82
C07D 417/04
C07D 417/06
Abstract:
Disclosed herein are compounds, pharmaceutical compositions, and related methods for the treatment of viral infection, including RNA viral infection in subjects. The compounds, pharmaceutical compositions, and methods can modulate the innate immune antiviral response in vertebrate cells, including activating the RIG-I pathway.