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Hongfan Fan Jin

from Oklahoma City, OK
Age ~48
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Also known as:
Hongfan F Jin, Jin Hongfan
Related to:
Jamie L Caldwell, 54Jin HongfanEdward Wilkins, 75Sarah Williams, 63Christopher Williams, 58Eugene Williams, 65Paul Williams
Connected to:
Aihua Jin, 52Aiwen J Jin, 67Alex Jin, 36Alice Jin, 34Anita Jin, 84Annie Jin, 56Ben Jin, 47Cathy Y Jin, 58Claire Y Jin, 28Daniel D Jin, 77

Hongfan Jin Phones & Addresses

  • Oklahoma City, OK
  • San Diego, CA
  • Madison, WI

Work

Company: Pfenex inc May 2017 to Sep 2018 Position: Senior scientist, molecular biology and clinical bioanalytical team leader

Education

Degree: Doctorates, Doctor of Philosophy School / High School: University of Oklahoma Health Sciences Center Specialities: Microbiology, Immunology

Skills

Molecular Biology • Protein Expression • Cell Culture • Biopharmaceuticals • Biotechnology • Microbiology • Bioinformatics • Life Sciences • Lifesciences • Protein Chemistry • Clinical Research • Bioanalytical Analysis • Biochemistry • High Throughput Screening • Metabolic Engineering • R&D • Transcriptomics • Vaccines

Ranks

Certificate: Clinical Trials Design and Management

Industries

Biotechnology

Resumes

Resumes

Hongfan Jin Photo 1

Director, Microbial Engineering

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Location:
San Diego, CA
Industry:
Biotechnology
Work:
Pfenex Inc May 2017 - Sep 2018
Senior Scientist, Molecular Biology and Clinical Bioanalytical Team Leader
Pfenex Inc May 2017 - Sep 2018
Group Leader, Clinical Bioanalytical and Molecular Biology
Pfenex Inc Dec 2009 - May 2017
Senior Scientist, Molecular Biology
The Dow Chemical Company 2001 - 2009
Senior Research Specialist, Project Leader
2001 - 2009
Director, Microbial Engineering
Education:
University of Oklahoma Health Sciences Center
Doctorates, Doctor of Philosophy, Microbiology, Immunology Nankai University
Bachelors, Bachelor of Science, Microbiology Institute of Botany, Academia Sinica, Beijing, P.r. China
Master of Science, Masters, Genetics
Skills:
Molecular Biology
Protein Expression
Cell Culture
Biopharmaceuticals
Biotechnology
Microbiology
Bioinformatics
Life Sciences
Lifesciences
Protein Chemistry
Clinical Research
Bioanalytical Analysis
Biochemistry
High Throughput Screening
Metabolic Engineering
R&D
Transcriptomics
Vaccines
Certifications:
Clinical Trials Design and Management

Publications

Us Patents

High Level Expression Of Recombinant Toxin Proteins

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US Patent:
8530171, Sep 10, 2013
Filed:
Mar 28, 2011
Appl. No.:
13/073955
Inventors:
Diane M. Retallack - Poway CA, US
Lawrence Chew - San Diego CA, US
Hongfan Jin - San Diego CA, US
Henry W. Talbot - San Diego CA, US
Assignee:
Pfenex Inc. - San Diego CA
International Classification:
C07K 14/195
C12P 21/00
G01N 33/53
US Classification:
435 71
Abstract:
The present invention relates to the field of recombinant toxin protein production in bacterial hosts. In particular, the present invention relates to production processes for obtaining high levels of a recombinant CRM197, Diphtheria Toxin, Pertussis Toxin, Tetanus Toxoid Fragment C, Cholera Toxin B, Cholera holotoxin, and Exotoxin A, from a bacterial host.

Process For Improved Protein Expression By Strain Engineering

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US Patent:
8603824, Dec 10, 2013
Filed:
Jul 26, 2005
Appl. No.:
11/189375
Inventors:
Thomas M. Ramseier - Poway CA, US
Hongfan Jin - San Diego CA, US
Charles H. Squires - Poway CA, US
Assignee:
Pfenex, Inc. - San Diego CA
International Classification:
C12N 15/67
C12N 15/63
C12N 15/64
C12N 15/65
C12N 15/52
US Classification:
435471, 435 691, 435 6, 435 71, 4352872
Abstract:
This invention is a process for improving the production levels of recombinant proteins or peptides or improving the level of active recombinant proteins or peptides expressed in host cells. The invention is a process of comparing two genetic profiles of a cell that expresses a recombinant protein and modifying the cell to change the expression of a gene product that is upregulated in response to the recombinant protein expression. The process can improve protein production or can improve protein quality, for example, by increasing solubility of a recombinant protein.

Methods For G-Csf Production In A Pseudomonas Host Cell

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US Patent:
20110245474, Oct 6, 2011
Filed:
Mar 30, 2011
Appl. No.:
13/076315
Inventors:
Hongfan Jin - San Diego CA, US
Lawrence Chew - San Diego CA, US
Assignee:
Pfenex Inc. - San Diego CA
International Classification:
C07K 14/535
C12P 21/00
US Classification:
530399, 435 691
Abstract:
The present invention relates to the field of recombinant protein production in bacterial hosts. It further relates to expression of soluble, active recombinant protein by using secretion signals to direct the protein to the periplasmic space of a bacterial cell. In particular, the present invention relates to a production process for obtaining soluble hG-CSF protein from a bacterial host.

Fusion Partners For Peptide Production

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US Patent:
20160159877, Jun 9, 2016
Filed:
Nov 30, 2015
Appl. No.:
14/954766
Inventors:
- San Diego CA, US
Adam Chapman - San Diego CA, US
Torben R. Bruck - Lakeside CA, US
Hongfan Jin - San Diego CA, US
International Classification:
C07K 14/635
C07K 14/62
C07K 14/535
C12N 9/64
Abstract:
The present invention relates to the field of medicine, in particular, to the production of large amounts of a soluble recombinant polypeptide as part of a fusion protein comprising an N-terminal fusion partner linked to the polypeptide of interest.

Process For Improved Protein Expression By Strain Engineering

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US Patent:
20140162279, Jun 12, 2014
Filed:
Nov 4, 2013
Appl. No.:
14/071273
Inventors:
- SAN DIEGO CA, US
HONGFAN JIN - SAN DIEGO CA, US
CHARLES H. SQUIRES - PAWAY CA, US
Assignee:
PFENEX INC. - SAN DIEGO CA
International Classification:
C12N 15/63
US Classification:
435 615
Abstract:
This invention is a process for improving the production levels of recombinant proteins or peptides or improving the level of active recombinant proteins or peptides expressed in host cells. The invention is a process of comparing two genetic profiles of a cell that expresses a recombinant protein and modifying the cell to change the expression of a gene product that is upregulated in response to the recombinant protein expression. The process can improve protein production or can improve protein quality, for example, by increasing solubility of a recombinant protein.
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Hongfan Fan Jin from Oklahoma City, OK, age ~48 Get Report