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Herbert Heyneker Phones & Addresses

  • Mill Valley, CA
  • 3341 Jackson St, San Francisco, CA 94118 (415) 447-4135
  • 2244 Steiner St, San Francisco, CA 94101 (415) 447-4137 (415) 776-1444
  • Bend, OR
  • Mountain View, CA
  • Hillsborough, CA
  • South San Francisco, CA
  • 2244 Steiner St, San Francisco, CA 94115 (415) 819-3858

Work

Company: Thuja capital Sep 2008 Address: Utrecht, the Netherlands Position: Adviser

Education

Degree: visiting scholar, dept. of Genetics School / High School: Stanford University 1992 to 1994

Skills

Biotechnology • Genomics • Molecular Biology • Biochemistry • Drug Discovery • Immunology • Cell Biology • Infectious Diseases • Vaccines • Antibodies • Purification

Interests

Career • Boating • Exercise • Investing • Outdoors • Electronics • Home Improvement • Reading • Music • Sports • Travel • Movies • Collecting • Home Decoration

Emails

Industries

Biotechnology

Resumes

Resumes

Herbert Heyneker Photo 1

Advisor

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Location:
3341 Jackson St, San Francisco, CA 94118
Industry:
Biotechnology
Work:
Thuja Capital - Utrecht, the Netherlands since Sep 2008
Adviser

Abingworth Jan 2003 - Jan 2008
Adviser

Eos Biotechnology May 1996 - Apr 2003
Founder and Chief Technology Officer

ProtoGene Jan 1994 - Apr 1996
Founder and Chairman of the Board

GlycoGen Mar 1990 - Nov 1992
Founder and CEO
Education:
Stanford University 1992 - 1994
visiting scholar, dept. of Genetics
UCSF 1975 - 1977
postdoctoral studies, Molecular Biology
Leiden University 1961 - 1975
PhD, Molecular Genetics
Skills:
Biotechnology
Genomics
Molecular Biology
Biochemistry
Drug Discovery
Immunology
Cell Biology
Infectious Diseases
Vaccines
Antibodies
Purification
Interests:
Career
Boating
Exercise
Investing
Outdoors
Electronics
Home Improvement
Reading
Music
Sports
Travel
Movies
Collecting
Home Decoration

Business Records

Name / Title
Company / Classification
Phones & Addresses
Herbert L. Heyneker
President
ARRAY TECHNOLOGIES
986 Celia Dr, Palo Alto, CA 94303
Herbert L. Heyneker
President
ARRAY TECHNOLOGIES, INC
225 Gtwy Blvd STE A, South San Francisco, CA 94080
Herbert L. Heyneker
President
WEBOLIGOS.COM, INC
2775 Sand Hl Rd, Menlo Park, CA 94025

Publications

Us Patents

Methods Of Making Antibody Heavy And Light Chains Having Specificity For A Desired Antigen

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US Patent:
7923221, Apr 12, 2011
Filed:
Apr 13, 1995
Appl. No.:
08/422187
Inventors:
Herbert L. Heyneker - Burlingame CA, US
William E. Holmes - Pacifica CA, US
Arthur D. Riggs - La Verne CA, US
Ronald B. Wetzel - San Francisco CA, US
Assignee:
Genentech, Inc - South San Francisco CA
City of Hope - Duarte CA
International Classification:
C12N 15/13
C12N 15/00
C12N 15/63
US Classification:
435 696, 4352521, 4352523, 43525233, 43525411, 43525421, 435 691, 435 697, 435 701, 435 7021, 435 711, 4353201, 435455, 435483, 435485, 435440, 435433, 435438
Abstract:
The invention relates to processes for producing an immunoglobulin or an immunologically functional immunoglobulin fragment containing at least the variable domains of the immunoglobulin heavy and light chains. The processes can use one or more vectors which produce both the heavy and light chains or fragments thereof in a single cell. The invention also relates to the vectors used to produce the immunoglobulin or fragment, and to cells transformed with the vectors.

Apparatus And Method For Concurrent Chemical Synthesis

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US Patent:
20020031833, Mar 14, 2002
Filed:
Jun 5, 2001
Appl. No.:
09/875204
Inventors:
Herbert Heyneker - San Francisco CA, US
Kim Ha - San Jose CA, US
David Steinmiller - Palo Alto CA, US
Victor Simonyi - Berkeley CA, US
International Classification:
G01N035/00
US Classification:
436/046000, 422/064000
Abstract:
This invention provides an apparatus for preparing chemical libraries. The apparatus includes (1) a carousel comprising a plurality of reaction mounts having at least one reaction well; (2) a rotator that rotates the carousel step-wise; (3) a fluid delivery system; (4) a drain system; and (5) a programmable computer that controls the operation of the apparatus, including the rotator, the fluid delivery system, the drain system and other systems in the apparatus. The preparation-of chemical libraries involves rotating the carousel through a plurality of stations. At each station, a physical step in a reaction protocol is carried out on the reaction wells of the mount docked at the station.

Methods And Compositions For Economically Synthesizing And Assembling Long Dna Sequences

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US Patent:
20030068643, Apr 10, 2003
Filed:
Nov 14, 2002
Appl. No.:
10/298081
Inventors:
Thomas Brennan - San Francisco CA, US
Herbert Heyneker - San Francisco CA, US
International Classification:
C12Q001/68
C12P019/34
US Classification:
435/006000, 435/091200
Abstract:
The present invention relates to a method for synthesizing and assembling long DNA sequences from short synthetic oligonucleotides. More specifically, the present invention is a cost-effective method for producing large segments of DNA of interest.

Methods And Compositions For Economically Synthesizing And Assembling Long Dna Sequences

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US Patent:
20030186226, Oct 2, 2003
Filed:
Mar 7, 2000
Appl. No.:
09/519927
Inventors:
Thomas Brennan - San Francisco CA, US
Herbert Heyneker - San Francisco CA, US
International Classification:
C12Q001/68
C12P013/14
C12P019/34
C07H021/04
US Classification:
435/006000, 435/091200, 536/025300
Abstract:
The present invention relates to a cost-effective method of assembling long DNA sequences from short synthetic oligonucleotides. More specifically, short oligonucleotides are synthesized in situ on a solid support and subsequently cleaved from the solid support prior to or during the assembly into the full-length DNA sequences.

Production Of Recombinant Polypeptides By Bovine Species And Transgenic Methods

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US Patent:
20050198698, Sep 8, 2005
Filed:
Nov 12, 2004
Appl. No.:
10/987587
Inventors:
Herman DeBoer - Roelofarendsveen, NL
Rein Strijker - Oegstgeest, NL
Herbert Heyneker - Hillsborough CA, US
Gerard Plantenburg - Voorschoten, NL
Sang Lee - Leiden, NL
Frank Pieper - Utrecht, NL
Paul Krimpenfort - Heemstede, NL
Assignee:
Pharming B.V., a Netherlands corporation - Leiden
International Classification:
A01K067/027
C07H021/04
US Classification:
800015000, 536023200
Abstract:
Transgenes for producing recombinant polypeptides transgenic bovine species. A transgene for producing recombinant polypeptides in the milk of transgenic bovine species comprises at least one expression regulation sequence, a secretory DNA sequence encoding a secretory signal sequence which is functional in mammary secretory cells of the bovine species and a recombinant DNA sequence encoding the recombinant polypeptide. Also included are methods for producing transgenic bovine species. The method includes introducing the above transgene into an embryonal target cell of a bovine species, transplanting the transgenic embryonic target cell formed thereby into a recipient bovine parent and identifying at least one female offspring which is capable of producing the recombinant polypeptide in its milk. The invention also includes transgenic bovine species capable of producing recombinant polypeptides in transgenic milk as well as the milk from such transgenic bovine species and food formulations containing one or more recombinant polypeptide. Methods are also provided for producing transgenic non-human mammals having a desirable phenotype. The method comprises first methylating a transgene followed by introduction into fertilized oocytes. The oocytes are then cultured to form pre-implantation embryos. Thereafter, at least one cell is removed from each of the pre-implantation embryos and the DNA digested with a restriction endonuclease capable of cleaving the methylated transgene but incapable of cleaving the unmethylated form of the transgene. Those pre-implantation embryos which have integrated the transgene contain DNA which is resistant to cleavage by the restriction endonuclease in the region containing the transgene.

Systems And Methods For Enhanced Scoda

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US Patent:
20110272282, Nov 10, 2011
Filed:
Nov 10, 2009
Appl. No.:
13/128387
Inventors:
Andrea Marziali - North Vancouver, CA
David John Broemeling - Vancouver, CA
Joel Pel - Vancouver, CA
Jason Donald Thompson - Vancouver, CA
Jaryn Perkins - Vancouver, CA
Thomas Willis - San Francisco CA, US
Herbert Heyneker - San Francisco CA, US
Darren Gray - La Jolla CA, US
Carolina Tropini - Redwood City CA, US
Assignee:
University of British Columbia - Vancouver, British Columbia
International Classification:
C07K 1/26
C25B 9/00
US Classification:
204456, 204450, 204600, 204547
Abstract:
Methods and apparatus for concentrating particles may be applied, for example, to concentrating DNA, RNA, proteins and the like. Proteins may be pre-treated to facilitate concentration by scodaphoresis. The pre-treatment may comprise, for example, heating or chemical treatment to denature and/or apply a net charge to the protein, binding handle particles to the protein and combinations thereof. High-conductivity samples may be subjected to a conductivity-reduction step to facilitate electrical injection of target particles into scodaphoresis media. The conductivity-reduction step may comprise a buffer exchange process or a salt extraction process, for example. Methods and apparatus can allow two or more different types of target particles to be extracted from the same sample and separately concentrated. These various aspects may be applied individually or in any combination.

Microfluidic Cell Separation In The Assay Of Blood

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US Patent:
20130143197, Jun 6, 2013
Filed:
Aug 12, 2011
Appl. No.:
13/816933
Inventors:
Herbert Heyneker - San Francisco CA, US
Assignee:
GPB SCIENTIFIC, LLC - Richmond VA
International Classification:
G01N 33/569
US Classification:
435 2, 4352872
Abstract:
The present invention is directed to methods for assaying blood samples to quantitate the types of white blood cells present. In addition, the invention includes equipment that can be used for these methods. One feature of the methodology is the use of micro fluidic devices for the separation of white blood cells from red blood cells.

Transgenic Bovines And Milk From Transgenic Bovines

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US Patent:
60138572, Jan 11, 2000
Filed:
Jun 5, 1995
Appl. No.:
8/464167
Inventors:
Herman A. Deboer - Roelofarendsveen, NL
Rein Strijker - Oegstgeest, NL
Herbert L. Heyneker - Hillsborough CA
Gerard Platenburg - Voorschoten, NL
Sang He Lee - Leiden, NL
Frank Pieper - Utrecht, NL
Paul J. A. Krimpenfort - Heemstede, NL
Assignee:
Pharming B.V. - Ca Leiden
International Classification:
A01K 67027
A01K 6700
C12P 2100
A23C 1110
US Classification:
800 15
Abstract:
Transgenes for producing recombinant polypeptides transgenic bovine species. A transgene for producing recombinant polypeptides in the milk of transgenic bovine species comprises at least one expression regulation sequence, a secretory DNA sequence encoding a secretory signal sequence which is functional in mammary secretory cells of the bovine species and a recombinant DNA sequence encoding the recombinant polypeptide. Also included are methods for producing transgenic bovine species. The method includes introducing the above transgene into an embryonal target cell of a bovine species, transplanting the transgenic embryonic target cell formed thereby into a recipient bovine parent and identifying at least one female offspring which is capable of producing the recombinant polypeptide in its milk. The invention also includes transgenic bovine species capable of producing recombinant polypeptides in transgenic milk as well as the milk from such transgenic bovine species and food formulations containing one or more recombinant polypeptide. Methods are also provided for producing transgenic non-human mammals having a desirable phenotype.
Herbert L Heyneker from Mill Valley, CA, age ~81 Get Report