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Hari Manev

from Chicago, IL
Age ~53

Hari Manev Phones & Addresses

  • 505 Lake Shore Dr, Chicago, IL 60611
  • Washington, DC
  • Pittsburgh, PA
  • 505 N Lake Shore Dr APT 3108, Chicago, IL 60611

Work

Position: Sales Occupations

Resumes

Resumes

Hari Manev Photo 1

Hari Manev

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Location:
Chicago, IL
Industry:
Research
Work:
University of Illinois at Chicago
Professor-Pharmacology Scientist
Skills:
Translational Medicine
Psychiatry
Cell Biology
In Vivo
Animal Models
Neuroscience
Confocal Microscopy
Aging
Cell
Dna
Epigenetics
Scientific Writing
Translational Research
Drug Discovery
Molecular Biology
Lifesciences
Neuropharmacology
In Vitro
Cancer
Pharmacology
Genetics
Biochemistry
Science
Physiology
Fluorescence Microscopy
Microscopy
Hari Manev Photo 2

Author

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Location:
Chicago, IL
Work:
Hari Manev
Author

Publications

Us Patents

Sulfated Lyso-Ganglioside Derivatives

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US Patent:
57958696, Aug 18, 1998
Filed:
Nov 2, 1995
Appl. No.:
8/530267
Inventors:
Aurelio Romeo - Rome, IT
Gunter Kirschner - Abano Terme, IT
Carlo Chizzolini - Padua, IT
Hari Manev - Pittsburgh PA
Laura Facci - Vicenza, IT
Assignee:
Fidia S.p.A. - Abano Terme
International Classification:
A61K 3170
C07H 1500
US Classification:
514 25
Abstract:
Semisynthetic analogues of gangliosides selected from the group consisting of N-sulfo-, N-hydrocarbyl-sulfonyl- and N-hydrocarbyloxy-sulfonyl-N,N'-dilyso-gangliosides and the N'-acyl derivatives thereof, N'-sulfo-, N'-hydrocarbylsulfonyl- and N'-hydrocarbyloxy-sulfonyl-N,N'-dilyso-gangliosides and the N-acyl derivatives thereof, N,N'-di or polysulfo-N,N'-di- or poly-lyso-gangliosides, N,N'-di- or polyhydrocarbylsulfonyl-N,N'-di- or poly-lyso-gangliosides and N,N'-di- or polyhydrocarbyloxy-N,N'-di- or poly-lyso-gangliosides, and functional derivatives thereof, and salts of these compounds, have protective activity against neurotoxicity induced by excitatory amino acids and are foreseen to be used in therapy in the nervous system and in modulating of the expression of determinants such as CD. sub. 4 on the surface of human cells in the immune system.

O-Sulfated Gangliosides And Lyso-Ganglioside Derivatives

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US Patent:
58497170, Dec 15, 1998
Filed:
Jan 31, 1996
Appl. No.:
8/530275
Inventors:
Aurelio Romeo - Rome, IT
Gunter Kirschner - Abano Terme, IT
Carlo Chizzolini - Padova, IT
Hari Manev - Pittsburgh PA
Laura Facci - Vicenza, IT
Assignee:
Fidia S.p.A. - Abano Terme
International Classification:
A61K 3170
C07H 1500
US Classification:
514 25
Abstract:
Disclosed are derivatives of gangliosides and of N-acyl-N-lyso-gangliosides, of N'-acyl-N'-lyso-gangliosides and N,N'-di- or poly-acyl-N,N'-di-lyso-gangliosides, in which at least one of the hydroxyl groups in the saccharide, sialic or ceramide residues is esterified with sulfuric acid, functional derivatives thereof, and their salts with either inorganic or organic bases and the acid addition salts, except persulfated derivatives at the hydroxyl, sialic and ceramide groups of the GM. sub. 1, GD. sub. 1a, GD. sub. 1b and GT. sub. 1b gangliosides. Such compounds have antineurotoxic and neurotogenic activity and may therefore be used in pharmaceutical preparations. Also a marked modulating effect on the expression of the CD. sub. 4 molecule in immune system cells has been shown.

Derivatives Of Neuraminic Acid

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US Patent:
56772858, Oct 14, 1997
Filed:
Apr 26, 1995
Appl. No.:
8/379602
Inventors:
Aurelio Romeo - Rome, IT
Gunter Kirschner - Abano Terme, IT
Hari Manev - Pittsburgh PA
Martino Trimarco - Padua, IT
Gino Toffano - Padua, IT
Assignee:
Fidia S.P.A. - Abano Terme
International Classification:
A61K 3170
A61K 3816
A61K 3814
C07H 1500
US Classification:
514 25
Abstract:
Provided are new derivatives of neuraminic acid of formula (I), where Ac represents an acyl residue of an aliphatic, araliphatic, aromatic, alicyclic, or heterocyclic carboxylic acid, including carboxylic amides, their 2-hydrocarbyl-glycosides, and their peracylated derivatives at the hydroxy groups of both these series of amides. These compositions are therapeutically useful in providing a protective effect against the neurotoxicity induced by excitatory amino acids, and can therefore be used in therapies of the central nervous system. ##STR1##.
Hari Manev from Chicago, IL, age ~53 Get Report