US Patent:
20130210805, Aug 15, 2013
Inventors:
Robert G. Aslanian - Rockaway NJ, US
Christopher W. Boyce - Flemington NJ, US
Brian A. McKittrick - New Vernon NJ, US
Kevin D. McCormick - Basking Ridge NJ, US
Anandan Palani - Bridgewater NJ, US
Jun Qin - Somerset NJ, US
Haiqun Tang - Belle Mead NJ, US
Dong Xiao - Warren NJ, US
Younong Yu - East Brunswick NJ, US
John P. Caldwell - Ringwood NJ, US
Elizabeth Helen Kelley - Lynnfield MA, US
Hongjun Zhang - Newton MA, US
Phieng Siliphaivanh - Newton MA, US
Rachel N. MacCoss - Oxford, GB
Joey L. Methot - Westwood MA, US
Jolicia Polivina Gauuan - Schenectady NY, US
Qin Jiang - Latham NY, US
Andrew J. Leyhane - Latham NY, US
Johny Biju - Piscataway NJ, US
Li Dong - Lawrenceville NJ, US
Xian Huang - Warren NJ, US
Ning Shao - Watchung NJ, US
Wei Zhou - Scotch Plains NJ, US
Pawan K. Dhondi - Elizabeth NJ, US
International Classification:
C07D 239/91
A61K 31/517
A61K 45/06
C07D 403/10
C07D 417/10
C07D 413/10
C07D 405/10
C07D 413/14
C07D 498/10
C07D 403/14
A61K 31/55
C07D 401/14
A61K 31/5395
C07D 471/04
C07D 401/10
US Classification:
51421207, 544284, 51426621, 5142662, 51426623, 544290, 51426624, 5142663, 544230, 540523, 514249, 544 66, 5142292, 51426622
Abstract:
This application provides for compounds of the formula Formula I or a pharmaceutically acceptable salt thereof, wherein the individual variables are defined herein, as well as processes to prepare these compounds, pharmaceutical compositions comprising the same and their use in treating disease state associated with the CRTHreceptor.