Inventors:
Piotr Karpinski - Lincoln Park NJ, US
Dimitris Papoutsakis - Acton MA, US
Guy Yowell - Boonton NJ, US
International Classification:
A61K 31/496
A61P 37/06
A61P 3/10
A61P 37/00
A61P 37/02
A61P 35/00
C07D 401/14
A61P 29/00
Abstract:
The invention provides acid addition salts of 3-(1.H.-indol-3-yl)-4-[2-(4-methyl-piperazin-1-yl)-quinazolin-4-yl]-pyrrole-2,5-dione, crystalline forms thereof, processes for the preparation thereof, pharmaceutical compositions comprising them and uses thereof in therapeutic treatment.