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George Tim Lountos

from Frederick, MD
Age ~46
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Also known as:
George T Lountos
Related to:
Sara M Ward, 42Tammy Ward, 55Tim LountosSpiridoula Lountos, 88Yiotis Lountos, 39
Connected to:
Blake Loup, 32Cassie K Loup, 40Ineta M Loup, 60Mary V Loup, 69Adam M Loupe, 30Alison A Loupe, 44Alton J Loupe, 61Elizabeth G Loupe, 74Jeff S Loupe, 74Joseph Loupe, 42

George Lountos Phones & Addresses

  • Frederick, MD
  • 311 Warren Ave, Thomasville, GA 31792 (404) 375-3180
  • Smyrna, GA
  • Atlanta, GA

Work

Company: National cancer institute at frederick May 2006 Position: Postdoctoral fellow

Education

Degree: PhD School / High School: Georgia Institute of Technology 2000 to 2005 Specialities: Chemistry

Skills

Protein Expression • Molecular Biology • Protein Chemistry • Fplc • X Ray Crystallography • Purification • Structural Biology • Biochemistry • Pcr • Drug Discovery • Protein Purification • Mass Spectrometry • Protein Engineering • Molecular Cloning • Assay Development • Drug Design • Laboratory • Cell • Uv/Vis • Sds Page • Crystallography • Site Directed Mutagenesis • Western Blotting • Fluorescence • Biophysics • Nmr • Protein Structure • Organic Chemistry • Enzymes • Polymerase Chain Reaction • Protein Crystallography • Structure Based Drug Design • Physical Chemistry • Enzyme Kinetics • Crystallization • High Throughput Screening • Enzyme Assays • Synchrotron X Ray Data Collection • Protein Structure Analysis • Structure Determination of Protein Inhib...

Languages

English • Greek

Interests

Education

Industries

Biotechnology

Resumes

Resumes

George Lountos Photo 1

Scientist I

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Location:
Gadsden, AL
Industry:
Biotechnology
Work:
National Cancer Institute at Frederick since May 2006
Postdoctoral Fellow
Education:
Georgia Institute of Technology 2000 - 2005
PhD, ChemistryThesis: Structural and Mechanistic Insights from High Resolution Crystal Structures of Toluene-4-Monooxygenase Catalytic Effector Protein, NAD(P)H Oxidase and Choline oxidase Advisor: Professor Allen M. Orville - crystallographic and mechanistic studies of the catalytic mechanism of flavoenzyme oxidases -served as graduate teaching assistant for courses in analytical and physical chemistry -7 peer-reviewed publications - supervised research of 1 undergraduate summer student and 1 lab technician Georgia Institute of Technology 1996 - 2000
BS, ChemistryUndergraduate research in Organic Chemistry Oxford Study Abroad Program (1999)
Skills:
Protein Expression
Molecular Biology
Protein Chemistry
Fplc
X Ray Crystallography
Purification
Structural Biology
Biochemistry
Pcr
Drug Discovery
Protein Purification
Mass Spectrometry
Protein Engineering
Molecular Cloning
Assay Development
Drug Design
Laboratory
Cell
Uv/Vis
Sds Page
Crystallography
Site Directed Mutagenesis
Western Blotting
Fluorescence
Biophysics
Nmr
Protein Structure
Organic Chemistry
Enzymes
Polymerase Chain Reaction
Protein Crystallography
Structure Based Drug Design
Physical Chemistry
Enzyme Kinetics
Crystallization
High Throughput Screening
Enzyme Assays
Synchrotron X Ray Data Collection
Protein Structure Analysis
Structure Determination of Protein Inhibitor Complexes
Interests:
Education
Languages:
English
Greek

Publications

Us Patents

Kinase Inhibitors, Compositions Thereof, And Methods Of Use Therewith

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US Patent:
20090018141, Jan 15, 2009
Filed:
Jun 9, 2008
Appl. No.:
12/135575
Inventors:
Robert Shoemaker - Boyds MD, US
John Cardellina - Walkersville MD, US
Michael Currens - Frederick MD, US
Sudhir Kondapaka - North Potomac MD, US
Yves Pommier - Bethesda MD, US
Andy Jobson - Rockville MD, US
Dominic Scudiero - Frederick MD, US
David Waugh - Walkersville MD, US
George Lountos - Frederick MD, US
Charles M. Cook - Mendham NJ, US
Guangtao Zhang - Princeton NJ, US
Andrew Colasanti - Scotch Plains NJ, US
Christopher R. Self - West Caldwell NJ, US
Janet Cicariello Cook - Mendham NJ, US
International Classification:
A61K 31/496
A61K 31/17
C07C 275/40
A61K 31/404
C07D 209/42
C07D 403/12
C12N 9/99
A61P 3/10
A61K 31/444
C07D 401/12
A61K 31/495
C07D 241/04
US Classification:
51425409, 564 51, 514597, 514419, 548492, 546265, 514332, 51425501, 544382, 544373, 435184
Abstract:
Provided herein are Compounds having the following structure:

Method Of Treating Hcv Infection With A Small Molecule Chk2 Inhibitor

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US Patent:
20140294767, Oct 2, 2014
Filed:
Oct 26, 2012
Appl. No.:
14/353976
Inventors:
- Bethesda MD, US
- Monmouth Junction NJ, US
Guangtao Zhang - Princeton NJ, US
Yves Pommier - Bethesda MD, US
Robert H. Shoemaker - Boyds MD, US
Michael Currens - Frederick MD, US
John Cardellina - Walkersville MD, US
Andrew Jobson - Balsall Common, GB
George Lountos - Frederick MD, US
Dominic Scudiero - Frederick MD, US
International Classification:
C07D 403/12
A61K 31/454
A61K 31/4184
C12N 9/96
A61K 31/404
A61K 45/06
A61K 31/4709
A61K 31/4178
C07D 401/12
C07D 209/42
US Classification:
424 854, 514313, 514323, 514394, 514397, 514414, 514419, 435188
Abstract:
A method of treating an Hepatitis C Virus infection in a patient, comprising providing a therapeutically effective amount, to a patient in need thereof, of a compound of Formula (I) or a pharmaceutically acceptable salt thereof, wherein: Gis a group of the formula or where n is 0, 1, 2, 3, or 4 and Het is a 5- or 6-membered heteroaryl group containing 1 to 4 heteroatoms independently chosen from N, O, and S, which Het is optionally substituted.
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George Tim Lountos from Frederick, MD, age ~46 Get Report