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George S Amato

from Cary, NC
Age ~62
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Also known as:
George M Amato, George Amsto
Phone and address:
103 Chapel Creek Ct, Cary, NC 27513
(910) 987-2772
Related to:
Camille L Amato, 67Salvatore AmatoLori D Sumter, 61Nina M Amato, 52Lorraine V HodgeMatthew J Amato, 58Kelly E Amato, 57Willa M DodsonTracee Farley, 61William W DodsonGregory W Dodson, 53Richard T Dodson, 89
Connected to:
Alex Amato, 34Anita L Amato, 92Anne C Amato, 68Annie Amato, 40Arthur J Amato, 84Athena C Amato, 44Bethany Amato, 39Camila Amato, 42Carly J Amato, 29Carol Amato, 60

George Amato Phones & Addresses

  • 103 Chapel Creek Ct, Cary, NC 27513 (910) 987-2772
  • 101 Ashley Dr, Cary, NC 27513 (919) 463-5422 (919) 460-1520
  • 230 Park St, Cary, NC 27511 (919) 460-1520
  • Norristown, PA
  • Astoria, NY
  • Wade, NC
  • Knoxville, TN
  • Bloomington, IN

Resumes

Resumes

George Amato Photo 1

Medicinal Chemist

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Location:
351 California St, San Francisco, CA 94104
Industry:
Biotechnology
Work:
Pfizer since Nov 2011
Principal Scientist
Icagen, Inc Apr 1996 - Oct 2011
Senior Scientist
Rhone-Poulenc Rorer Jul 1992 - Feb 1996
Senior Scientist
Education:
Indiana University Bloomington 1989 - 1992
Postdoc, Organic Synthesis The University of Connecticut 1984 - 1989
Ph.D., Medicinal Chemistry Carnegie Mellon University 1980 - 1984
B.S., Chemistry
Skills:
Medicinal Chemistry
Drug Discovery
Ion Channels
Organic Chemistry
Analytical Chemistry
Lc Ms
Ehs
Drug Development
Interests:
Education
Children
Languages:
Italian
George Amato Photo 2

George Amato

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George Amato Photo 3

George Amato

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Business Records

Name / Title
Company / Classification
Phones & Addresses
George Amato
Manager
Abby Funeral Directors
1076 Madison Ave, New York, NY 10028
(212) 288-1900, (212) 288-5717
George Amato
Manager
FRANK E CAMPBELL FUNERAL
Funeral Homes · Funeral Homes & Funeral Svcs
1076 Madison Ave, New York, NY 10028
(212) 288-3500, (212) 288-5717
George Amato
Medical Doctor, Scientist
Neusentis
Commercial Physical Research
4222 Emperor Blvd, Durham, NC 27703
PO Box 14487, Durham, NC 27709
(919) 941-5206
George M. Amato
Treasurer, Secretary
Sanctuary Acquisition, Inc

Publications

Us Patents

Pyridine-Substituted Benzanilides As Potassium Ion Channel Openers

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US Patent:
6495550, Dec 17, 2002
Filed:
Feb 2, 2001
Appl. No.:
09/776791
Inventors:
Paul Christopher Fritch - Durham NC
George Salvatore Amato - Cary NC
Assignee:
ICAgen, Inc. - Durham NC
International Classification:
C07D40102
US Classification:
5142355, 51425505, 514256, 514332, 514336, 514341, 514343, 514352, 544124, 544333, 544405, 546255, 5462727, 5462764, 5462834, 546309
Abstract:
The present invention provides a genus of pyridine-substituted benzanilides that are useful as openers of potassium ion channels. The compounds of the invention are of use in both therapeutic and diagnostic methods.

Bisarylamines As Potassium Channel Openers

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US Patent:
6593349, Jul 15, 2003
Filed:
Mar 11, 2002
Appl. No.:
10/095617
Inventors:
George Salvatore Amato - Cary NC
Assignee:
ICAgen, Inc. - Durham NC
International Classification:
C07D40102
US Classification:
514333, 514256, 514338, 514373, 514379, 514405, 544333, 546256, 5462711, 5462721, 5462757, 548213, 548246, 5483621
Abstract:
Compounds, compositions and methods are provided which are useful in the treatment of diseases through the modulation of potassium ion flux through voltage-dependent potassium channels. More particularly, the invention provides bisarylamines, compositions and methods that are useful in the treatment of central or peripheral nervous system disorders (e. g. , migraine, ataxia, Parkinsons disease, bipolar disorders, trigeminal neuralgia, spasticity, mood disorders, brain tumors, psychotic disorders, myokymia, seizures, epilepsy, hearing and vision loss, Alzheimers disease, age-related memory loss, learning deficiencies, anxiety and motor neuron diseases) and as neuroprotective agents (e. g. , to prevent stroke and the like) by opening potassium channels associated with the onset or recurrence of the indicated conditions.

Pyrimidines As Novel Openers Of Potassium Ion Channels

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US Patent:
7205307, Apr 17, 2007
Filed:
Nov 27, 2002
Appl. No.:
10/305706
Inventors:
George S. Amato - Cary NC, US
Paul C. Fritch - Cary NC, US
Assignee:
Icagen, Inc. - Durham NC
International Classification:
C07D 239/26
C07D 239/30
A61K 31/505
A61P 25/08
A61P 29/00
C07D 239/34
C07D 239/52
US Classification:
514256, 544322, 544324, 544300, 544301, 544309, 544310, 544316, 544319
Abstract:
The present invention provides a genus of pyrimidine amides that are useful as openers of potassium ion channels. The compounds of the invention are of use in both therapeutic and diagnostic methods.

Fused Ring Heterocycles As Potassium Channel Modulators

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US Patent:
7223768, May 29, 2007
Filed:
Sep 10, 2004
Appl. No.:
10/937958
Inventors:
George Salvatore Amato - Cary NC, US
Assignee:
Icagen, Inc. - NC
International Classification:
A61K 31/517
C07D 239/72
US Classification:
5142663, 51426631, 544287, 544289
Abstract:
Compounds, compositions and methods are provided which are useful in the treatment of diseases through the modulation of potassium ion flux through voltage-dependent potassium channels. More particularly, the invention provides quinazolinone, compositions and methods that are useful in the treatment of central or peripheral nervous system disorders (e. g. , migraine, ataxia, Parkinson's disease, bipolar disorders, trigeminal neuralgia, spasticity, mood disorders, brain tumors, psychotic disorders, myokymia, seizures, epilepsy, hearing and vision loss, Alzheimer's disease, age-related memory loss, learning deficiencies, anxiety and motor neuron diseases, maintaining bladder control or treating urinary incontinence) and as neuroprotective agents (e. g. , to prevent stroke and the like) by modulating potassium channels associated with the onset or recurrence of the indicated conditions.

Fused Ring Heterocycles As Potassium Channel Modulators

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US Patent:
7741332, Jun 22, 2010
Filed:
Apr 26, 2007
Appl. No.:
11/740831
Inventors:
George Salvatore Amato - Cary NC, US
Assignee:
Icagen, Inc. - Durham NC
International Classification:
A61K 31/517
C07D 239/72
US Classification:
5142663, 51426631, 544287, 544289
Abstract:
Compounds, compositions and methods are provided which are useful in the treatment of diseases through the modulation of potassium ion flux through voltage-dependent potassium channels. More particularly, the invention provides quinazolinone, compositions and methods that are useful in the treatment of central or peripheral nervous system disorders (e. g. , migraine, ataxia, Parkinson's disease, bipolar disorders, trigeminal neuralgia, spasticity, mood disorders, brain tumors, psychotic disorders, myokymia, seizures, epilepsy, hearing and vision loss, Alzheimer's disease, age-related memory loss, learning deficiencies, anxiety and motor neuron diseases, maintaining bladder control or treating urinary incontinence) and as neuroprotective agents (e. g. , to prevent stroke and the like) by modulating potassium channels associated with the onset or recurrence of the indicated conditions.

Fused Ring Heterocycles As Potassium Channel Modulators

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US Patent:
8329713, Dec 11, 2012
Filed:
Apr 9, 2010
Appl. No.:
12/757909
Inventors:
George Salvatore Amato - Cary NC, US
Assignee:
Icagen Inc. - Durham NC
International Classification:
A61K 31/517
C07D 239/72
US Classification:
5142663, 51426631, 544287, 544289
Abstract:
Compounds, compositions and methods are provided which are useful in the treatment of diseases through the modulation of potassium ion flux through voltage-dependent potassium channels. More particularly, the invention provides quinazolinone, compositions and methods that are useful in the treatment of central or peripheral nervous system disorders (e. g. , migraine, ataxia, Parkinson's disease, bipolar disorders, trigeminal neuralgia, spasticity, mood disorders, brain tumors, psychotic disorders, myokymia, seizures, epilepsy, hearing and vision loss, Alzheimer's disease, age-related memory loss, learning deficiencies, anxiety and motor neuron diseases, maintaining bladder control or treating urinary incontinence) and as neuroprotective agents (e. g. , to prevent stroke and the like) by modulating potassium channels associated with the onset or recurrence of the indicated conditions.

Heterocycles As Potassium Channel Modulators

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US Patent:
8431608, Apr 30, 2013
Filed:
Feb 16, 2010
Appl. No.:
12/706574
Inventors:
Thomas Eugene Christos - Wake Forest NC, US
George S. Amato - Cary NC, US
Robert N. Atkinson - Raleigh NC, US
Maria Graciela Barolli - Morrisville NC, US
Mark J. Suto - Chapel Hill NC, US
Assignee:
Icagen Inc. - Durham NC
International Classification:
A61K 31/4188
C07D 235/00
US Classification:
514393, 5483027
Abstract:
Compounds, compositions and methods are provided which are useful in the treatment of diseases through the modulation of potassium ion flux through voltage-dependent potassium channels. More particularly, the invention provides heterocycles, compositions and methods that are useful in the treatment of central or peripheral nervous system disorders (e. g. , migraine, ataxia, Parkinson's disease, bipolar disorders, trigeminal neuralgia, spasticity, mood disorders, brain tumors, psychotic disorders, myokymia, seizures, epilepsy, seizure, retinal degeneration, hearing and vision loss, Alzheimer's disease, age-related memory loss, learning deficiencies, anxiety, neuronal degeneration and motor neuron diseases, maintaining bladder control or treating urinary incontinence) and as neuroprotective agents (e. g. , to prevent stroke and the like) by modulating potassium channels associated with the onset or recurrence of the indicated conditions.

Quinazolinones As Potassium Channel Modulators

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US Patent:
20040198724, Oct 7, 2004
Filed:
Dec 23, 2003
Appl. No.:
10/746205
Inventors:
James Thomas - Efland NC, US
George Amato - Cary NC, US
Assignee:
ICAgen, Inc. - Durham NC
International Classification:
A61K031/542
A61K031/519
A61K031/517
US Classification:
514/223800, 514/264100, 514/265100, 514/266300, 544/011000, 544/279000, 544/286000
Abstract:
Compounds, compositions and methods are provided which are useful in the treatment of diseases through the modulation of potassium ion flux through voltage-dependent potassium channels. More particularly, the invention provides quinazolinone, compositions and methods that are useful in the treatment of central or peripheral nervous system disorders (e.g., migraine, ataxia, Parkinson's disease, bipolar disorders, trigeminal neuralgia, spasticity, mood disorders, brain tumors, psychotic disorders, myokymia, seizures, epilepsy, hearing and vision loss, Alzheimer's disease, age-related memory loss, learning deficiencies, anxiety and motor neuron diseases) and as neuroprotective agents (e.g., to prevent stroke and the like) by modulating potassium channels associated with the onset or recurrence of the indicated conditions.
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George S Amato from Cary, NC, age ~62 Get Report