Inventors:
Michael Augello - Marlboro NJ
Sheila M. Dell - New Hope PA
George A. Agyilirah - Plainsboro NJ
George E. Reier - Somerset NJ
Assignee:
FMC Corporation - Philadelphia PA
International Classification:
A61K 920
Abstract:
Rapidly disintegrating and readily suspendible tablets and their method of preparation are disclosed in which there is a therapeutic amount of a pharmacologically active ingredient, 1 to 6 percent croscarmellose sodium, 10 to 50 percent microcrystalline cellulose, and 10 to 50 percent of a coprocessed additive consisting essentially of 75 to 95 percent microcrystalline cellulose and 5 to 25 percent calcium, sodium alginate complex. The tablets are suitable for oral administration of measured-dose suspensions of either water soluble or water insoluble pharmaceuticals.