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Geoff Gz Zhang

from Vernon Hills, IL
Age ~58
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Also known as:
Geoff G Zhang, Geoff Z Zhang, Guangzhong Z Zhang, Guangzho G Zhang, Guang Zhong Zhang, Guangzhong G Zhang, N Zhang, George Zhang, Guang-Zhong Zhang, N Zhuang
Phone and address:
1600 Cypress Pointe Dr, Indian Creek, IL 60061
(224) 587-3849
Related to:
Lixiao L Zhu, 61Jian Zheng, 65Jingzhu ZhangWu Zhuang, 70
Connected to:
Agata Zhang, 47Aiguo Zhang, 48Aiyi Zhang, 29Al D Zhang, 54Andi Zhang, 42Angeli W Zhang, 55Bao S ZhangBaoguo Zhang, 54Becky Q Zhang, 68Benyuan Zhang, 61

Geoff Zhang Phones & Addresses

  • 1600 Cypress Pointe Dr, Vernon Hills, IL 60061 (224) 587-3849
  • 1014 Dawes St, Libertyville, IL 60048 (847) 968-5447
  • Park City, IL
  • Saint Paul, MN
  • Lafayette, CO
  • Minneapolis, MN
  • Eden Prairie, MN
  • Lane, IL

Resumes

Resumes

Geoff Zhang Photo 1

Senior Research Fellow

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Location:
1372 Maidstone Dr, Vernon Hills, IL 60061
Industry:
Pharmaceuticals
Work:
Drug Product Development Abbvie
Senior Research Fellow
Materials Science Research and Development Abbvie Jan 2013 - Jul 2013
Senior Research Fellow, Head
Abbott Sep 2012 - Dec 2012
Senior Research Fellow, Head
Abbott Jan 2010 - Sep 2012
Associate Research Fellow, Project Leader
Abbott Jun 2009 - Jan 2010
Associate Research Fellow, Project Leader
Education:
University of Minnesota 1994 - 1998
Doctorates, Doctor of Philosophy Fudan University 1984 - 1988
Bachelors, Bachelor of Science, Chemistry
Skills:
Drug Delivery
Drug Development
Formulation
Pharmaceutical Industry
Drug Discovery
Pharmaceutical Research
Technology Transfer
Pharmaceutics
Analytical Chemistry
Hplc
Quality By Design
Glp
Chemistry
Gmp
Clinical Development
Validation
Chromatography
Lc Ms
R&D
Biopharmaceuticals
Ind
Uv/Vis
Interests:
Football
Horses
Exercise
Sweepstakes
Home Improvement
Sports
Watching Basketball
Fishing
Home Decoration
Watching Sports
Cooking
Cruises
Outdoors
Electronics
Fitness
Music
Family Values
Movies
Collecting
Christianity
Travel
Boating
Investing
Traveling
Basketball
Self Improvement
Watching Football
Languages:
Mandarin
English
Geoff Zhang Photo 2

Advisor

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Work:
Ccba Organization
Advisor

Publications

Us Patents

Methods Of Manufacturing Crystalline Forms Of Rapamycin Analogs

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US Patent:
7820812, Oct 26, 2010
Filed:
Jul 23, 2007
Appl. No.:
11/781807
Inventors:
Shekhar Viswanath - Vernon Hills IL, US
Larry Bartelt - Highland Park IL, US
Robert Leanna - Grayslake IL, US
Michael Rasmussen - Racine WI, US
Madhup Dhaon - Mundelein IL, US
Rodger Henry - Wildwood IL, US
Thomas Borchardt - Kenosha WI, US
Shuang Chen - Gurnee IL, US
Geoff Zhang - Libertyville IL, US
Assignee:
Abbott Laboratories - Abbott Park IL
International Classification:
C07D 498/18
US Classification:
540456
Abstract:
A process for preparing a crystalline rapamycin analog includes: combining the rapamycin analog with an organic medium to form a mixture; incubating the mixture until the rapamycin analog crystallizes; and recovering the crystalline rapamycin analog. The organic medium can be a solvent, and the process can include causing the rapamycin analog to dissolve into the solvent, and incubating the solvent until the rapamycin analog crystallizes. The following can also be performed: forming a slurry of crystalline rapamycin analog; stirring the rapamycin analog mixture until the rapamycin analog crystallizes; saturating the rapamycin analog solution; forming a supersaturated rapamycin analog solution; combining an antisolvent with the rapamycin analog and the solvent to form a biphasic mixture, and incubating the biphasic mixture to cause a liquid-liquid phase split.

Crystalline Forms Of Rapamycin Analogs

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US Patent:
8030326, Oct 4, 2011
Filed:
Sep 20, 2010
Appl. No.:
12/886410
Inventors:
Shekhar Viswanath - Vernon Hills IL, US
Larry Bartelt - Highland Park IL, US
Robert Leanna - Grayslake IL, US
Michael Rasmussen - Racine IL, US
Madhup Dhaon - Mundelein IL, US
Rodger Henry - Wildwood IL, US
Thomas Borchardt - Kenosha WI, US
Shuang Chen - Gurnee IL, US
Geoff Zhang - Libertyville IL, US
Assignee:
Abbott Laboratories - Abbott Park IL
International Classification:
A61K 31/395
A61P 37/06
US Classification:
514291
Abstract:
Provided is a rapamycin analog composition including a crystalline form of a rapamycin analog. The crystal can be a hydrate. dehydrate, solvate, or desolvate. The rampamycin analog can have a structure of Formula 1, which is optionally a prodrug, salt, derivative, or combination thereof:.

Methods Of Manufacturing Crystalline Forms Of Rapamycin Analogs

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US Patent:
8034926, Oct 11, 2011
Filed:
Sep 20, 2010
Appl. No.:
12/886398
Inventors:
Shekhar Viswanath - Vernon Hills IL, US
Larry Bartelt - Highland Park IL, US
Robert Leanna - Grayslake IL, US
Michael Rasmussen - Racine WI, US
Madhup Dhaon - Mundelein IL, US
Rodger Henry - Wildwood IL, US
Thomas Borchardt - Kenosha WI, US
Shuang Chen - Gurnee IL, US
Geoff Zhang - Libertyville IL, US
Assignee:
Abbott Laboratories - Abbott Park IL
International Classification:
C07D 498/18
US Classification:
540456
Abstract:
A process for preparing a crystalline rapamycin analog includes: combining the rapamycin analog with an organic medium to form a mixture; incubating the mixture until the rapamycin analog crystallizes; and recovering the crystalline rapamycin analog. The organic medium can be a solvent, and the process can include causing the rapamycin analog to dissolve into the solvent, and incubating the solvent until the rapamycin analog crystallizes. The following can also be performed: forming a slurry of crystalline rapamycin analog; stirring the rapamycin analog mixture until the rapamycin analog crystallizes; saturating the rapamycin analog solution; forming a supersaturated rapamycin analog solution; combining an antisolvent with the rapamycin analog and the solvent to form a biphasic mixture, and incubating the biphasic mixture to cause a liquid-liquid phase split.

Ritonavir Bis-Hydrochloride

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US Patent:
8598216, Dec 3, 2013
Filed:
Dec 16, 2011
Appl. No.:
13/328043
Inventors:
Maurizio Acquasaliente - Kent, GB
Didier Houllemare - West Malling, GB
Geoff Zhang - Vernon Hills IL, US
Pulla Singam - Northbrook IL, US
John Morris - Grayslake IL, US
Kennan Marsh - Lake Forest IL, US
Martin Babcock - Pleasant Prairie WI, US
John Pavlina - Pleasant Prairie WI, US
Yi Shi - Libertyville IL, US
Yuchuan Gong - Waukegan IL, US
Assignee:
Abbvie Inc. - North Chicago IL
International Classification:
A61K 31/426
A61K 31/41
US Classification:
514365, 514183, 514359
Abstract:
The invention relates to ritonavir bis-hydrochloride, processes for the preparation of the ritonavir bis-hydrochloride, pharmaceutical compositions containing the ritonavir bis-hydrochloride and made from it, and methods of using the ritonavir bis-hydrochloride to inhibit HIV protease or enhance the pharmacokinetics of compounds which are metabolized by cytochrome P3A4.

Salts Of Fenofibric Acid And Pharmaceutical Formulations Thereof

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US Patent:
20050148594, Jul 7, 2005
Filed:
Jun 30, 2004
Appl. No.:
10/880851
Inventors:
Russell Cink - Grayslake IL, US
Joseph Paterson - Vernon Hills IL, US
Yi Gao - Vernon Hills IL, US
Geoff Zhang - Libertyville IL, US
Michelle Long - Libertyville IL, US
John Morris - Grayslake IL, US
Joerg Rosenberg - Ellerstadt, DE
International Classification:
A61K031/495
A61K031/192
A61K031/205
C07C211/62
C07C059/66
US Classification:
514252120, 514554000, 514571000, 544358000, 562471000, 424472000
Abstract:
In one aspect, the present invention relates to a formulation in the form of molecular dispersion comprising i) fenofibric acid, a physiologically acceptable salt or derivative thereof and optionally other active substances, ii) a binder component comprising at least one enteric binder, and optionally iii) other physiologically acceptable excipients. In a second aspect, the present invention relates to novel salts of fenofibric acid that are photostable when compared to other salts of fenofibric acid.

(1S,5S)-3-(5,6-Dichloro-3-Pyridinyl)-3,6-Diazabicyclo[3.2.0]Heptane

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US Patent:
20060035936, Feb 16, 2006
Filed:
Jul 7, 2005
Appl. No.:
11/176087
Inventors:
Michael Buckley - McHenry IL, US
Jianguo Ji - Libertyville IL, US
Geoff Zhang - Libertyville IL, US
Rodger Henry - Wildwood IL, US
Weili Wang - Buffalo Grove IL, US
Gregory Wayne - Vernon Hills IL, US
Wenke Li - Gurnee IL, US
Timothy Towne - Lindenhurst IL, US
Steven Wittenberger - Mundelein IL, US
Steven Hannick - Highland Park IL, US
Brian Kotecki - Oak Creek WI, US
Bryan Macri - Gurnee IL, US
Timothy Robbins - Grayslake IL, US
International Classification:
A61K 31/4439
US Classification:
514339000, 546276700
Abstract:
The present invention discloses (1S,5S)-3-(5,6-dichloro-3-pyridinyl)-3,6-diazabicyclo[3.2.0]heptane, salts thereof, and its use to treat pain and other disorders associated with the nicotinic acetylcholine receptor.

(1S,5S)-3-(5,6-Dichloropyridin-3-Yl)-3,6-Diazabicyclo[3.2.0]Heptane Benzenesulfonate

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US Patent:
20060035937, Feb 16, 2006
Filed:
Jul 7, 2005
Appl. No.:
11/176088
Inventors:
Gregory Wayne - Vernon Hills IL, US
Sean Mellican - Gurnee IL, US
Geoff Zhang - Libertyville IL, US
David Willcox - Ridgefield CT, US
Jeffrey Breting - Evanston IL, US
International Classification:
A61K 31/4439
C07D 487/02
US Classification:
514339000, 546276700
Abstract:
The present invention relates to the salt (1S,5S)-3-(5,6-dichloropyridin-3-yl)-3,6-diazabicyclo[3.2.0]heptane benzenesulfonate and to methods of preparing the salt.

Preparation Of Pyridonecarboxylic Acid Antibacterials

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US Patent:
20060128686, Jun 15, 2006
Filed:
Jul 28, 2005
Appl. No.:
11/191319
Inventors:
Anthony Haight - Wadsworth IL, US
David Barnes - Lake Villa IL, US
Geoff Zhang - Libertyville IL, US
International Classification:
A61K 31/4709
C07D 401/14
C07D 215/36
C07D 215/16
US Classification:
514210210, 546156000, 548950000, 546268400, 546307000
Abstract:
A process for making 1-(6-amino-3,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-7-(3-hydroxyazetidin-1-yl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid, and therapeutically acceptable salts thereof, and intermediates used in the process are disclosed.
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Geoff Gz Zhang from Vernon Hills, IL, age ~58 Get Report