Inventors:
Thomas M. Jessell - New York NY
Gabi Tremml - New York NY
Assignee:
The Trustees of Columbia University in the City of New York - New York NY
International Classification:
C12N 506
US Classification:
435377, 435375, 435368, 514 2, 4241981
Abstract:
This invention provides a composition comprising an amount of a purified protein selected from a group consisting of bone morphogenetic protein 4, bone morphogenetic protein, bone morphogenetic protein 7, dorsalin-1 and combinations thereof effective to stimulate neural crest cell differentiation and an acceptable carrier. This invention provides different uses of this composition.