Inventors:
Eric D. Schwoebel - Woburn MA, US
James D. Harper - Boston MA, US
Martha S. Petrovick - Barre MA, US
Frances E. Nargi - Littleton MA, US
Todd H. Rider - Littleton MA, US
Kristine E. Hogan - Danvers MA, US
Richard H. Mathews - Chelmsford MA, US
Joseph Lacirignola - Beverly MA, US
Mark Hennessy - Cambridge MA, US
Trina R. Vian - Groton MA, US
Rose M. Joseph - Westford MA, US
Raymond S. Uttaro - Lexington MA, US
Shaun Berry - Chelmsford MA, US
Bernadette Johnson - Hollis NH, US
Mark A. Hollis - Concord MA, US
Assignee:
Massachusetts Institute of Technology - Cambridge MA
International Classification:
G01N 33/53
Abstract:
The invention described herein provides methods for the detection of soluble antigens. In particular, the methods provide for the detection of soluble proteins and chemicals. In addition, the invention provides methods of detecting a nucleic acid sequence in a sample. Also described is an emittor cell comprising an Fc receptor and an emittor molecule for the detection of a target particle in a sample wherein the target particle to be detected is bound by one or more antibodies. Also provided is an optoelectronic sensor device for detecting a target particle in a plurality of samples.