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Fathy D Majadly

from Frederick, MD
Age ~60
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Also known as:
Fathy Michelle Majadly, Fathy Michelle Wichman Majadly, Fathy M Majadly, Majadly Fathy, Fathy Y
Phone and address:
4963 Flossie Ave, Frederick, MD 21703
(301) 662-9314
Related to:
Ahlam Majadly, 24Michelle Wichman, 58
Connected to:
Nabeel R Majahid, 40Nadeem Majaj, 69Javier Majak, 63John J Majak, 79Erin L Majakey, 39Saja Majali, 56Samuel Majam, 49John A Majane, 83Kimberly A Majane, 56Angelina Majano, 40

Fathy Majadly Phones & Addresses

  • 4963 Flossie Ave, Frederick, MD 21703 (301) 662-9314
  • 5640 Wade Ct, Frederick, MD 21703

Publications

Us Patents

Poly-Gamma-Glutamic Conjugates For Eliciting Immune Responses Directed Against Bacilli

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US Patent:
7803386, Sep 28, 2010
Filed:
Jun 4, 2004
Appl. No.:
10/559825
Inventors:
Rachel Schneerson - Bethesda MD, US
Stephen Leppla - Bethesda MD, US
John B. Robbins - Chevy Chase MD, US
Joseph Shiloach - Rockville MD, US
Darrell Liu - Bethesda MD, US
Fathy Majadly - Frederick MD, US
Assignee:
The United States of America as represented by the Secretary of the Department of Health and Human Services - Washington DC
International Classification:
A61K 39/02
A61K 49/00
A61K 39/07
US Classification:
4242341, 424 91, 424 92, 4241841, 4241921, 4241931, 42419711, 4242031, 4242461, 4242781
Abstract:
Immunogenic compositions and methods for eliciting an immune response against and other bacilli are provided that include immunogenic conjugates of a poly-γ-glutamic acid (γPGA) polypeptide of , or of another that expresses a γPGA polypeptide. The γPGA conjugates elicit an effective immune response against , or against another , in mammalian hosts to which the conjugates are administered.

Conjugates Of Surface Proteins As Malaria Vaccines

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US Patent:
8383133, Feb 26, 2013
Filed:
Oct 15, 2007
Appl. No.:
12/444963
Inventors:
Rachel Schneerson - Bethesda MD, US
Yimin Wu - Frederick MD, US
Louis Miller - Cabin John MD, US
Fathy D. Majadly - Frederick MD, US
John B. Robbins - New York NY, US
Assignee:
The United States of America, as Represented by the Secretary, Department of Health and Human Services - Washington DC
International Classification:
A61K 39/015
C07K 14/445
US Classification:
4242721, 4242681, 530350
Abstract:
Conjugates of ookinete surface protein Pfs25 are provided that are efficacious as vaccines against , the most severe form of malaria. Conjugates of ookinete surface protein Pvs25 for use as a vaccine against are also provided. Methods for preparing the conjugates, which comprise the ookinete surface protein bound onto itself or onto another protein by a linking group, are also provided.

Multicomponent Vaccine For Malaria Providing Long-Lasting Immune Responses Against Plasmodia

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US Patent:
8444996, May 21, 2013
Filed:
Oct 1, 2009
Appl. No.:
13/121574
Inventors:
Rachel Schneerson - Bethesda MD, US
John B. Robbins - New York NY, US
Fathy Majadly - Frederick MD, US
Christopher P. Mocca - Columbia MD, US
Jerry Keith - Olney NC, US
Louis Miller - Cabin John MD, US
Ruth Nussenzweig - New York NY, US
Darrell T. Liu - Bethesda MD, US
Assignee:
The United States of America, as represented by the Secretary, Department of Health and Human Services - Washington DC
New York University - New York NY
International Classification:
A61K 39/015
A61K 39/385
US Classification:
4241931, 4241941, 4242651, 4242721
Abstract:
Disclosed are immunogenic conjugates which elicit an immune response to proteins. In particular examples, the proteins include sexual stage surface proteins, circumsporozoite protein (CSP), or immunogenic portions of CSP. Also provided herein are immunogenic compositions including one or more of the disclosed immunogenic conjugates and a pharmaceutically acceptable carrier. Further provided is a method of eliciting an immune response to in a subject, comprising administering to the subject an immunogenic composition disclosed herein.

Methods For Preparing Immunogenic Conjugates

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US Patent:
8481048, Jul 9, 2013
Filed:
Oct 20, 2009
Appl. No.:
12/582420
Inventors:
Rachel Schneerson - Bethesda MD, US
Fathy Majadly - Frederick MD, US
Stephen H. Leppla - Bethesda MD, US
John B. Robbins - Bethesda MD, US
Darrell T. Liu - Bethesda MD, US
Joseph Shiloach - Rockville MD, US
Assignee:
The United States of America as represented by the Secretary of the Department of Health and Human Services, National Institutes of Health - Rockville MD
International Classification:
A61K 39/385
C07K 17/00
A61P 37/04
US Classification:
4241941, 4241931, 530345, 530405
Abstract:
Methods for making an immunogenic conjugate that includes a hapten or an antigen covalently linked to a carrier. The methods include reacting a first agent with a dihydrazide resulting in a hydrazine-modified first agent, wherein the first agent is a hapten, an antigen or a carrier; reacting a second agent with a benzaldehyde compound resulting in a benzaldehyde-modified second agent, wherein the second agent is a hapten, an antigen or a carrier, provided that the first agent or the second agent is a carrier; and reacting the hydrazine-modified first agent with the benzaldehyde-modified second agent resulting in an immunogenic conjugate comprising a hapten or an antigen covalently linked to a carrier via a hydrazone linkage.

Methods For Preparing Immunogenic Conjugates

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US Patent:
20050271675, Dec 8, 2005
Filed:
Dec 6, 2004
Appl. No.:
11/005851
Inventors:
Rachel Schneerson - Bethesda MD, US
Fathy Majadly - Frederick MD, US
Stephen Leppla - Bethesda MD, US
John Robbins - Bethesda MD, US
Darrell Liu - Bethesda MD, US
Joseph Shiloah - Rockville MD, US
International Classification:
A61K039/00
C07K014/005
C07K014/195
US Classification:
424185100, 530403000
Abstract:
Methods for making an immunogenic conjugate that includes a hapten or an antigen covalently linked to a carrier. The methods include reacting a first agent with a dihydrazide resulting in a hydrazino-modified first agent, wherein the first agent is a hapten, an antigen or a carrier; reacting a second agent with a benzaldehyde compound resulting in a benzaldehyde-modified second agent, wherein the second agent is a hapten, an antigen or a carrier, provided that the first agent or the second agent is a carrier; and reacting the hydrazine-modified first agent with the benzaldehyde-modified second agent resulting in an immunogenic conjugate comprising a hapten or an antigen covalently linked to a carrier via a hydrazone linkage.

Conjugates Of Plasmodium Falciparum Surface Proteins As Malaria Vaccines

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US Patent:
20130129777, May 23, 2013
Filed:
Jan 25, 2013
Appl. No.:
13/750495
Inventors:
The United States of America as represented by the Secretary, Department of Health and Human Services - Bethesda MD, US
Yimin Wu - Frederick MD, US
Louis Miller - Cabin John MD, US
Fathy Majadly - Frederick MD, US
John B. Robbins - New York City NY, US
Assignee:
The United States of America as represented by the Secretary, Department of Health and Human Service - Bethesda MD
International Classification:
C07K 14/705
C07K 14/21
US Classification:
42419711, 530405, 4241931, 530404
Abstract:
Conjugates of ookinete surface protein Pfs25 are provided that are efficacious as vaccines against , the most severe form of malaria. Conjugates of ookinete surface protein Pvs25 for use as a vaccine against are also provided. Methods for preparing the conjugates, which comprise the ookinete surface protein bound onto itself or onto another protein by a linking group, are also provided.

Multicomponent Vaccine For Malaria Providing Long-Lasting Immune Responses Against Plasmodia

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US Patent:
20130216570, Aug 22, 2013
Filed:
Apr 25, 2013
Appl. No.:
13/870547
Inventors:
The United States of America, as represented by the Secretary, Department of Health and Human Services - , US
New York University - , US
John B. Robbins - New York NY, US
Fathy Majadly - Frederick MD, US
Christopher P. Mocca - Columbia MD, US
Jerry Keith - Olney MD, US
Louis Miller - Cabin John MD, US
Ruth Nussenzweig - New York NY, US
Darrell T. Liu - Bethesda MD, US
Assignee:
New York University - New York NY
Services - Bethesda MD
International Classification:
C07K 14/00
US Classification:
4241931, 530363, 530367, 530350
Abstract:
Disclosed are immunogenic conjugates which elicit an immune response to proteins. In particular examples, the proteins include sexual stage surface proteins, circumsporozoite protein (CSP), or immunogenic portions of CSP. Also provided herein are immunogenic compositions including one or more of the disclosed immunogenic conjugates and a pharmaceutically acceptable carrier. Further provided is a method of eliciting an immune response to in a subject, comprising administering to the subject an immunogenic composition disclosed herein.

Conjugates Of Plasmodium Falciparum Surface Proteins As Malaria Vaccines

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US Patent:
20150050314, Feb 19, 2015
Filed:
Oct 29, 2014
Appl. No.:
14/527676
Inventors:
- Bethesda MD, US
Yimin Wu - Frederick MD, US
Louis Miller - Cabin John MD, US
Fathy Majadly - Frederick MD, US
John B. Robbins - New York NY, US
Assignee:
The United States of America as represented by the Secretary, Department of Health and Human Service - Bethesda MD
International Classification:
C07K 14/445
US Classification:
4241931, 530405, 530404
Abstract:
Conjugates of ookinete surface protein Pfs25 are provided that are efficacious as vaccines against , the most severe form of malaria. Conjugates of ookinete surface protein Pvs25 for use as a vaccine against are also provided. Methods for preparing the conjugates, which comprise the ookinete surface protein bound onto itself or onto another protein by a linking group, are also provided.
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Fathy D Majadly from Frederick, MD, age ~60 Get Report