Search

Ethan S Burstein

from San Diego, CA
Age ~64
Get Report
Also known as:
Ehtan Burstein
Phone and address:
4168 Sturgeon Ct, San Diego, CA 92130
(858) 481-1693
Related to:
Sheila M Mccluster, 69David R Mcalmond, 49
Connected to:
Alan T Burstein, 59Albert Burstein, 101Chad D Burstein, 34Cindi H Burstein, 52Ester Burstein, 67Gordon L Burstein, 82Heather J Burstein, 57Herman Burstein, 106Janet H Burstein, 91Jay A Burstein, 69

Ethan Burstein Phones & Addresses

  • 4168 Sturgeon Ct, San Diego, CA 92130 (858) 481-1693
  • 3834 Creststone Pl, San Diego, CA 92130 (858) 481-1693 (858) 720-0406
  • 13707 Ruette Le Parc, Del Mar, CA 92014 (858) 481-1693
  • Framingham, MA
  • South Burlington, VT
  • Medford, MA

Work

Company: Acadia pharmaceuticals Position: Director

Industries

Biotechnology

Resumes

Resumes

Ethan Burstein Photo 1

Director

View page
Location:
San Diego, CA
Industry:
Biotechnology
Work:
ACADIA Pharmaceuticals
Director

Business Records

Name / Title
Company / Classification
Phones & Addresses
Ethan Burstein
Director
JB Therapeutics, Inc.
Biotechnology · Mfg Pharmaceutical Preparations
508 Dudley Rd, Newton Center, MA 02459
100 Riv Rdg Dr, Norwood, MA 02062
4168 Sturgeon Ct, San Diego, CA 92130
(617) 413-3020

Publications

Us Patents

G-Protein Coupled Receptors High-Throughput Functional Assay

View page
US Patent:
20050123964, Jun 9, 2005
Filed:
Nov 2, 2004
Appl. No.:
10/980885
Inventors:
Ethan Burstein - San Diego CA, US
Fabrice Piu - San Diego CA, US
Jian-Nong Ma - San Diego CA, US
Jacques Weissman - Carlsbad CA, US
David Weiner - San Diego CA, US
Audra Scully - Carlsbad CA, US
Norman Nash - San Diego CA, US
Tracy Spalding - San Diego CA, US
Erika Currier - San Diego CA, US
International Classification:
C12Q001/68
C07H021/04
C07K014/705
C12N015/85
US Classification:
435006000, 435069100, 435455000, 435320100, 435325000, 530350000, 536023500
Abstract:
Disclosed herein are methods for enabling or improving functional assays of G-protein coupled receptors through the use of co-expression of helper genes. In some cases, chimeras linking the regulatory domain of the rap1B protein to the effector region of the ras oncogene are used in conjuction with existing functional assays for cellular proliferation. Furthermore, overexpression of other genes can further augment the enabling properties of ras/rap chimeras.

Compounds Useful For The Treatment And Prevention Of Pain And Screening Methods Therefor

View page
US Patent:
20060217370, Sep 28, 2006
Filed:
Feb 21, 2006
Appl. No.:
11/359209
Inventors:
Ethan Burstein - San Diego CA, US
Leila Malik - Copenhagen, DK
Nicholas Kelly - Bagsvaerd, DK
International Classification:
A61K 31/551
C07D 487/22
US Classification:
514219000, 540494000, 540555000
Abstract:
The present invention relates to the composition of compounds having the generic structure: and to a method of treatment or prevention of pain using the above compounds.

Use Of N-Desmethylclozapine And Related Compounds As Dopamine Stabilizing Agents

View page
US Patent:
20060252744, Nov 9, 2006
Filed:
Apr 3, 2006
Appl. No.:
11/397248
Inventors:
Ethan Burstein - San Diego CA, US
International Classification:
A61K 31/554
A61K 31/553
A61K 31/551
A61K 31/55
US Classification:
514211130, 514217000, 514220000
Abstract:
Disclosed herein is the use of N-desmethylclozapine (NDMC) and related compounds to treat a variety of neuropsychiatric diseases including psychosis. It is shown that NDMC and related compounds are agonists or partial agonists at D2 and D3 dopamine receptors and thus may be effective as a dopamine stabilizing agent, allowing it to be used to treat or provide reduced incidence of Extrapyramidal symptoms (EPS) and/or tardive dyskinesias (TD). Also disclosed is administering NDMC and related compounds in combination with other anti-psychotic agents.

Bicyclic-Nitrogen Compounds As Modulators Of Ghrelin Receptor And Uses Thereof

View page
US Patent:
20070213359, Sep 13, 2007
Filed:
Dec 29, 2006
Appl. No.:
11/618724
Inventors:
Ethan Burstein - San Diego CA, US
Anne Knapp - Frederiksberg C., DK
Roger Olsson - Bunkeflostrand, SE
Jorgen Eskildsen - Copenhagen, DK
Fredrik Ek - Lund, SE
Assignee:
ACADIA Pharmaceuticals Inc. - San Diego CA
International Classification:
C07D 471/02
A61K 31/4745
A61K 31/405
C07D 403/02
US Classification:
514300000, 514419000, 546113000, 548465000, 548495000, 514414000
Abstract:
Disclosed herein are compounds of Formula I as defined herein, or a pharmaceutically acceptable salt, ester, amide, or prodrug thereof, that modulates the activity of a ghrelin receptor. Disclosed herein are also methods of treating diseases or conditions that comprise administering to a subject in need thereof a therapeutically effective amount of a compound of Formula I.

G-Protein Coupled Receptors High-Throughput Functional Assay

View page
US Patent:
20080280303, Nov 13, 2008
Filed:
May 12, 2008
Appl. No.:
12/119119
Inventors:
Ethan S. Burstein - San Diego CA, US
Fabrice Piu - San Diego CA, US
Jian-Nong Ma - San Diego CA, US
Jacques Weissman - Carlsbad CA, US
David M. Weiner - San Diego CA, US
Audra L. Scully - Carlsbad CA, US
Norman Nash - San Diego CA, US
Tracy Spalding - San Diego CA, US
Erika Currier - San Diego CA, US
International Classification:
C12Q 1/68
G01N 33/53
US Classification:
435 6, 435 72
Abstract:
Disclosed herein are methods for enabling or improving functional assays of G-protein coupled receptors through the use of co-expression of helper genes. In some cases, chimeras linking the regulatory domain of the rap1B protein to the effector region of the ras oncogene are used in conduction with existing functional assays for cellular proliferation. Furthermore, overexpression of other genes can further augment the enabling properties of ras/rap chimeras.

Par2-Modulating Compounds And Their Use

View page
US Patent:
20080318960, Dec 25, 2008
Filed:
May 16, 2006
Appl. No.:
11/435817
Inventors:
Ethan Burstein - San Diego CA, US
Anne Eeg Knapp - Frederiksberg C, DK
International Classification:
A61K 31/502
C07D 237/30
A61P 9/00
A61P 29/00
A61P 11/00
A61P 1/00
A61P 19/00
A61P 25/00
A61P 17/00
A61P 27/00
A61P 35/04
US Classification:
514248, 544237, 435 29
Abstract:
The present invention relates to compounds, and uses thereof, having the chemical formula:or a pharmaceutically acceptable salt or prodrug thereof, wherein the compound modulates the activity of PAR2 or a PAR2 subtype and thereby may be used to treat or prevent diseases involving abnormal PAR2 or PAR2 subtype activity.

Enabling Methods To Identify Allosteric Modulators Of Receptor Activity

View page
US Patent:
20090209525, Aug 20, 2009
Filed:
Dec 19, 2008
Appl. No.:
12/340393
Inventors:
Tracy A Spalding - San Diego CA, US
Mark R. Brann - Del Mar CA, US
Robert E. Davis - San Diego CA, US
Ethan S. Burstein - San Diego CA, US
International Classification:
A61K 31/551
C12Q 1/68
G01N 33/53
A61K 31/538
A61K 31/445
A61K 31/195
A61K 31/46
A61K 31/4439
A61K 31/4025
US Classification:
514220, 435 6, 435 71, 5142305, 514317, 514563, 514304, 514342, 514422
Abstract:
A method developed to identify receptor modulators, involving providing a mutant receptor, wherein said mutant receptor has a mutation that alters the activity of said mutant receptor compared to a wild type receptor; contacting said mutant receptor with a candidate compound; and determining whether said candidate compound modulates the activity of said mutant receptor.

Imidazol (1,2-A)Pyridines And Related Compounds With Activity At Cannabinoid Cb2 Receptors

View page
US Patent:
20110206607, Aug 25, 2011
Filed:
May 9, 2008
Appl. No.:
12/599306
Inventors:
Roger Olsson - Bunkeflostrand, SE
Ethan Burstein - San Diego CA, US
Anne Eeg Knapp - Frederiksberg, DK
Jorgen Eskildsen - Copenhagen, DK
Joel Castillo - Malmo, SE
James Nairne - St. Albans, GB
Veronique Morisson-Iveson - Amersham, GB
Edward Robins - London, GB
Alex Gibson - Oxford, GB
International Classification:
A61K 49/00
C07D 471/04
A61K 31/437
C07F 7/18
A61K 31/695
C07D 487/04
A61K 31/519
A61K 31/4985
A61P 43/00
A61P 25/00
A61P 29/00
C12N 5/00
G01N 33/53
US Classification:
424 181, 546121, 514300, 546 14, 514 63, 544281, 5142591, 544350, 514249, 544333, 514256, 435375, 435 72
Abstract:
Disclosed herein are compounds of Formula (I), or a pharmaceutically acceptable salt, ester, amide, thereof; and methods of modulating the activity of a cannabinoid CB2 receptor comprising contacting a compound of Formula I with the cannabinoid CB2 receptor. Also disclosed are methods of imaging of a tissue by positron emission tomography, the method comprising administering to the subject a compound of Formula I, wherein the compound comprises a radioisotope. Also disclosed are methods of measuring the relative concentration of cannabinoid CB2 receptors in tissue of a subject, by using a compound of Formula I which comprises a radioisotope. In addition, method of diagnosing a disorder in a subject are disclosed.
Control profile
Ethan S Burstein from San Diego, CA, age ~64 Get Report