Search

Erin M Schuman

from Yorba Linda, CA
Get Report
Also known as:
Erin Margaret Schuman, Erin Chuman, Erin Schuman, Erin Laurent, Schuman Erin
Related to:
Lucille A DyerSusan M Arant, 85Rj SchumanJohn Avenson, 56Perry A Avenson, 27Kay J Laurent, 60Gilles J Laurent, 64Rod J Schuman, 91Nancy T Jang, 51Catherine S Avenson, 57
Connected to:
Adam R Schumann, 44Alex Schuman, 35Alexandra M Schuman, 37Alison K Schumann, 45Alissa A Schumann, 47Anita L Schuman, 118Anne L Schuman, 78Anthony I Schumann, 68April Schumann, 45Arthur Schuman, 84

Erin Schuman Phones & Addresses

  • Yorba Linda, CA
  • 766 Oak Knoll Ave, Pasadena, CA 91106 (626) 792-8055
  • Minnetonka, MN
  • Palo Alto, CA
  • Monrovia, CA
  • Bloomington, IN
  • Huntington Beach, CA

Publications

Us Patents

Methods For Proteomic Profiling Using Non-Natural Amino Acids

View page
US Patent:
20060216760, Sep 28, 2006
Filed:
Dec 21, 2005
Appl. No.:
11/314323
Inventors:
Daniela Dieterich - Pasadena CA, US
David Tirrell - Pasadena CA, US
Erin Schuman - Pasadena CA, US
Aaron Link - Austin TX, US
Assignee:
California Institute of Technology - Pasadena CA
International Classification:
G01N 33/53
C07K 1/02
US Classification:
435007500, 530409000
Abstract:
The invention provides methods, reagents and systems for incorporating non-natural amino acids into proteins, preferably in vivo, using the endogenous protein synthesis machinery of an organism. The incorporated non-natural amino acids contain reactive groups for further chemical reagents, which may serve as a “handle” to enrich the proteins or fragments thereof in a number of uses, such as proteomic analysis, imaging of diseased tissues/cells, etc.

Use Of Non-Canonical Amino Acids As Metabolic Markers For Rapidly-Dividing Cells

View page
US Patent:
20100247433, Sep 30, 2010
Filed:
Oct 16, 2006
Appl. No.:
11/581713
Inventors:
David Tirrell - Pasadena CA, US
Daniela C. Dieterich - Pasadena CA, US
Aaron J. Link - Austin TX, US
Erin Schuman - Pasadena CA, US
Assignee:
California Institute of Technology - Pasadena CA
International Classification:
A61K 51/04
A61K 49/00
A61K 31/655
A61K 31/4164
A61K 31/56
A61K 31/7076
A61K 31/445
A61K 38/46
G01N 33/53
US Classification:
424 165, 424 91, 514151, 514398, 514169, 514 46, 514328, 424 946, 435 71
Abstract:
The invention provides methods, reagents and systems to preferentially mark fast-proliferating cells/tissues (such as cancer), by incorporating non-natural amino acids into proteins, preferably in vivo, using the endogenous protein synthesis machinery of an organism. The incorporated non-natural amino acids contain reactive groups for further chemical reagents, which may serve as a “handle” to for a number of uses, such as imaging of cancer cells, targeting drugs to preferentially kill cancer cells, and proteomic analysis in the context of large scale or high throughput screening for candidate drug leads that affects the proliferation of a target cell, etc.

Detection Of Protein Expression In Vivo Using Fluorescent Puromycin Conjugates

View page
US Patent:
20060057069, Mar 16, 2006
Filed:
Jun 7, 2005
Appl. No.:
11/147813
Inventors:
Harry Green - Berkeley CA, US
Richard Roberts - South Pasadena CA, US
Erin Schuman - Pasadena CA, US
William Smith - La Jolla CA, US
Bruce Hay - Los Angeles CA, US
Assignee:
CALIFORNIA INSTITUTE OF TECHNOLOGY - Pasadena CA
International Classification:
A61K 49/00
C07K 14/47
US Classification:
424009600, 530352000
Abstract:
Disclosed is a class of reagents for examining protein expression in vivo that does not require transfection, radiolabeling, or the prior choice of a candidate gene. Further, a series of puromycin conjugates was constructed bearing various labeling moieties. These conjugates were readily incorporated into expressed protein products in cell lysates in vitro and efficiently cross cell membranes to function in protein synthesis in vivo as indicated by flow cytometry, selective enrichment studies, and western analysis. The present invention demonstrates that labeled-puromycin conjugates offer a general means to examine protein expression in vivo.

Methods For Proteomic Profiling Using Non-Natural Amino Acids

View page
US Patent:
20210223252, Jul 22, 2021
Filed:
Oct 9, 2020
Appl. No.:
17/067028
Inventors:
- Pasadena CA, US
David Tirrell - Pasadena CA, US
Erin Schuman - Pasadena CA, US
Aaron J. Link - Pasadena CA, US
Assignee:
California Institute of Technology - Pasadena CA
International Classification:
G01N 33/58
G01N 33/68
G01N 33/50
C07K 7/06
Abstract:
The invention provides methods, reagents and systems for incorporating non-natural amino acids into proteins, preferably in vivo, using the endogenous protein synthesis machinery of an organism. The incorporated non-natural amino acids contain reactive groups for further chemical reagents, which may serve as a “handle” to enrich the proteins or fragments thereof in a number of uses, such as proteomic analysis, imaging of diseased tissues/cells, etc.

Methods For Proteomic Profiling Using Non-Natural Amino Acids

View page
US Patent:
20170292958, Oct 12, 2017
Filed:
Apr 24, 2017
Appl. No.:
15/495414
Inventors:
- Pasadena CA, US
David Tirrell - Pasadena CA, US
Erin Schuman - Pasadena CA, US
Aaron J. Link - Pasadena CA, US
Assignee:
California Institute of Technology - Pasadena CA
International Classification:
G01N 33/68
Abstract:
The invention provides methods, reagents and systems for incorporating non-natural amino acids into proteins, preferably in vivo, using the endogenous protein synthesis machinery of an organism. The incorporated non-natural amino acids contain reactive groups for further chemical reagents, which may serve as a “handle” to enrich the proteins or fragments thereof in a number of uses, such as proteomic analysis, imaging of diseased tissues/cells, etc.
Control profile
Erin M Schuman from Yorba Linda, CA Get Report