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Enzo R Paoletti

from Piercefield, NY
Deceased
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Also known as:
Enzo E Paoletti, Donnette M Paoletti, Enzo Poletti, O I
Related to:
Herbert E Schnipper, 99Simone P Albrecht, 57Donnette M Paoletti, 77Phillip J Albrecht, 56Karma Paoletti, 54Donnette M Padletti, 51Judith L Saren, 72Marco O Paoletti, 51Dana F Schnipper, 73Sherilyn W Albrecht, 77Debra D Bamberger, 69
Connected to:
Adam B Paoletti, 40Ann M Paoletti, 67Anthony M Paoletti, 55Betty M Paoletti, 66Fernando A Paoletti, 82Giovanni G Paoletti, 64Jules M Paoletti, 69Rita M Paoletti, 100Robert D Paoletti, 59Rose A Paoletti, 33

Enzo Paoletti Phones & Addresses

  • Piercefield, NY
  • Albany, NY
  • 297 Murray Ave, Delmar, NY 12054 (518) 439-7611
  • 4 Furman Pl, Delmar, NY 12054 (518) 439-0898
  • 20 Gull Pond Rd, Tupper Lake, NY 12986 (518) 359-7506
  • 4 Furman Pl, Delmar, NY 12054 (518) 466-8637

Work

Position: Sales Occupations

Education

Degree: Associate degree or higher

Resumes

Resumes

Enzo Paoletti Photo 1

President And Chief Executive Officer

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Location:
Albany, NY
Industry:
Biotechnology
Work:
V-Core Technologies
President and Chief Executive Officer
Skills:
Start Ups
Science
Drug Discovery
Life Sciences
Strategic Planning
Public Speaking
Immunology
Research
Enzo Paoletti Photo 2

Enzo Paoletti

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Business Records

Name / Title
Company / Classification
Phones & Addresses
Enzo Paoletti
V-CORE TECHNOLOGIES, INC
20 Gull Pond Rd, Piercefield, NY 12973
PO Box 140, Piercefield, NY 12973

Publications

Us Patents

Recombinant Avipox Virus

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US Patent:
6340462, Jan 22, 2002
Filed:
May 31, 1995
Appl. No.:
08/455345
Inventors:
Enzo Paoletti - Delmar NY
Assignee:
Health Research, Inc. - Albany NY
International Classification:
A61K 39275
US Classification:
4241991, 424 932, 4352351, 4353201, 435236
Abstract:
The present invention provides a method for inducing an immunological response in a vertebrate to a pathogen by inoculating the vertebrate with a synthetic recombinant avipox virus modified by the presence, in a non-essential region of the avipox genome, of DNA from any source which encodes for and expresses an antigen of the pathogen. The present invention further provides a synthetic recombinant avipox virus modified by the insertion therein of DNA from any source, and particularly from a non-avipox source, into a non-essential region of the avipox genome.

Equine Herpesvirus Type 1 Glyocoprotein D (Ehv-1Gd)

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US Patent:
6395283, May 28, 2002
Filed:
Nov 21, 2000
Appl. No.:
09/717577
Inventors:
Enzo Paoletti - Delmar NY
Assignee:
Health Research, Inc. - Rensselaer NY
International Classification:
A61K 39245
US Classification:
4242291, 4242041, 4241381, 435 911, 435 691, 514 44, 530300, 536 2372
Abstract:
What is described is a recombinant poxvirus, such as vaccinia virus, fowipox virus and canarypox virus, containing foreign DNA from herpesvirus. In one embodiment, the foreign DNA is expressed in a host by the production of a herpesvirus glycoprotein. In another embodiment, the foreign DNA is expressed in a host by the production of at least two, pdrticularly two or three, herpesvirus glycoproteins. What is also described is a vaccine containing the recombinant poxvirus for inducing an immunological response in a host animal inoculated with the vaccine. By the present invention, the barrier of maternal immunity in a newborn offspring can be overcome or avoided.

Vaccina Virus Comprising Cytokine And/Or Tumor Associated Antigen Genes

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US Patent:
6537594, Mar 25, 2003
Filed:
Mar 24, 2000
Appl. No.:
09/535370
Inventors:
Enzo Paoletti - Delmar NY
James Tartaglia - Schenectady NY
William I. Cox - Troy NY
Assignee:
Virogenetics Corporation - Troy NY
International Classification:
A61F 200
US Classification:
424932, 435 691, 435 693, 435 695, 435 6951, 435 6952, 435 701, 435 703, 4353201, 514 44, 424 936, 424 932, 4241911
Abstract:
Attenuated recombinant viruses containing DNA coding for a cytokine and/or a tumor associated antigen, as well as methods and compositions employing the viruses, are disclosed and claimed. The recombinant viruses can be NYVAC or ALVAC recombinant viruses. The DNA can code for at least on of: human tumor necrosis factor; nuclear phosphoprotein p53, wildtype or mutant; human melanoma-associated antigen; IL-2; IFN; IL-4; GNCSF; IL-12; B7; erb-B-2 and carcinoembryonic antigen. The recombinant viruses and gene products therefrom are useful for cancer therapy.

Immunodeficiency Recombinant Poxvirus

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US Patent:
6596279, Jul 22, 2003
Filed:
Aug 14, 1998
Appl. No.:
09/136159
Inventors:
Enzo Paoletti - Delmar NY
James Tartaglia - Schenectady NY
William I. Cox - East Greenbush NY
Robert Gallo - Baltimore MD
Genoveffa Franchini - Washington DC
Assignee:
Virogenetics Corporation - Troy NY
International Classification:
A61K 3912
US Classification:
4241991, 4241881, 4242081, 4242021, 4242321, 4353201
Abstract:
Attenuated recombinant viruses containing DNA encoding an immunodeficiency virus and/or CTL antigen, as well as methods and compositions employing the viruses, expression products therefrom, and antibodies generated from the viruses or expression products, are disclosed and claimed. The recombinant viruses can be NYVAC or ALVAC recombinant viruses. The DNA can code for at least one of: HIV1gag(+pro)(IIIB), gp120(MN)(+transmembrane), nef(BRU)CTL, pol(IIIB)CTL, ELDKWA or LDKW epitopes, preferably HIV1gag(+pro)(IIIB), gp120(MN) (+transmembrane), two (2) nef(BRU)CTL and three (3) pol(IIIB)CTL etpitopes; or two ELDKWA in gp120 V3 or another region or in gp160. The two (2) nef(BRU)CTL and three (3) pol(IIIB)CTL epitopes are preferably CTL1, CTL2, pol1, pol2 and pol3. The recombinant viruses and gene products therefrom and antibodies generated by the viruses and gene products have several preventive, therapeutic and diagnostic uses. DNA from the recombinant viruses are useful as probes or, for generating PCR primers or for immunization.

Methods For Avoiding Maternal Immunity

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US Patent:
6605465, Aug 12, 2003
Filed:
Mar 8, 2002
Appl. No.:
10/094440
Inventors:
Enzo Paoletti - Delmar NY
Assignee:
Health Research, Inc. - Renesselaer NY
International Classification:
C12N 1500
US Classification:
4353201, 435 691, 435 6, 435 5, 435 9133
Abstract:
What is described is a recombinant poxvirus, such as vaccinia virus, fowlpox virus and canarypox virus, containing foreign DNA from herpesvirus. In one embodiment, the foreign DNA is expressed in a host by the production of a herpesvirus glycoprotein. In another embodiment, the foreign DNA is expressed in a host by the production of at least two, particularly two or three, herpesvirus glycoproteins. What is also described is a vaccine containing the recombinant poxvirus for inducing an immunological response in a host animal inoculated with the vaccine. By the present invention, the barrier of maternal immunity in a newborn offspring can be overcome or avoided.

Recombinant Poxvirus Cytomegalovirus, Compositions, And Uses

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US Patent:
6632438, Oct 14, 2003
Filed:
Jul 26, 2001
Appl. No.:
09/916963
Inventors:
Enzo Paoletti - Delmar NY
Steven E. Pincus - East Greenbush NY
William I. Cox - Troy NY
Elizabeth K. Kauffmann - Averill Park NY
Assignee:
Virogenetics Corporation - Troy NY
International Classification:
A61K 3912
US Classification:
4241991, 4242041, 4242301, 4242321, 4352351, 4353201, 530300, 5303881, 536 2372
Abstract:
Attenuated recombinant viruses containing DNA encoding an HCMV antigen, as well as methods and compositions employing the viruses, expression products therefrom, and antibodies generated from the viruses or expression products, are disclosed and claimed. The recombinant viruses can be NYVAC or ALVAC recombinant viruses. The recombinant viruses and gene products therefrom and antibodies generated by the viruses and gene products have several preventive, therapeutic and diagnostic uses. The DNA of the recombinant viruses can be used as probes or for generating PCR primers.

Pox Virus Comprising Dna Sequences Encoding Cea And B7 Antigen

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US Patent:
6780407, Aug 24, 2004
Filed:
Sep 15, 2000
Appl. No.:
09/663667
Inventors:
Enzo Paoletti - Delmar NY
James Tartaglia - Schenectady NY
William I. Cox - Troy NY
Assignee:
Aventis Pasteur - Swiftwater PA
International Classification:
A01N 6300
US Classification:
424 932, 424 936, 4241851, 4241991, 4353201
Abstract:
Attenutated recombinant viruses containing DNA coding for a cytokine and/or a tumor associated antigen, as well as methods and compositions employing the viruses, are disclosed and claimed. The recombinant viruses can be NYVAC or ALVAC recombinant viruses. The DNA can code for at least one of: human tumor necrosis factor; nuclear phosphoprotein p53, wiltype or mutant; human melanoma-associated antigen; IL-2; IFN; IL-4; GMCSF; IL-12; B7; erb-B-2 and carcinoembryonic antigen. The recombinant viruses and gene products therefrom are useful for cancer therapy.

Poxvirus-Rabies Recombinants And Compositions And Methods Employing The Recombinants

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US Patent:
7144578, Dec 5, 2006
Filed:
Sep 13, 2001
Appl. No.:
09/951061
Inventors:
Enzo Paoletti - Delmar NY, US
James Tartaglia - Aurora, CA
Jill Taylor - Albany NY, US
Russell Gettig - Averill Park NY, US
Assignee:
Connaught Technology Corporation - Greenville DE
International Classification:
A61K 39/275
A61K 39/285
C12N 7/01
C12N 15/863
C12N 15/47
US Classification:
4241991, 435 691, 435 693, 4352351, 4353201, 4242241, 4242321
Abstract:
Recombinant viruses containing DNA coding for a rabies virus antigen, such as rabies virus G are disclosed and claimed. The recombinant viruses can be NYVAC or ALVAC recombinant viruses. The recombinant viruses and gene products therefrom are useful for eliciting an immunological against rabies virus, and, the gene products and antibodies elicited thereby are useful in assays.

Wikipedia

Enzo Paoletti

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Enzo Paoletti is an Italian scientist who devised a strategy to produce recombinant DNA vaccines. Working with his colleague Dennis Panicali at the New York State department of ...

Recombinant DNA Vaccine

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Enzo Paoletti and Dennis Panicali at the New York State department of Health, devised a Strategy to produce recombinant DNA vaccines by using genetic engineering techniques.
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Enzo R Paoletti from Piercefield, NYDeceased Get Report