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Elizabeth A Reap

from Durham, NC
Age ~65

Elizabeth Reap Phones & Addresses

  • 12 Swallows Ridge Ct, Durham, NC 27713 (919) 403-5459
  • Chapel Hill, NC
  • 106 Twin Oaks, Pittsboro, NC 27312 (919) 929-3947
  • Oak Park, IL
  • Deerfield, IL
  • Clemson, SC
  • 12 Swallows Ridge Ct, Durham, NC 27713

Work

Position: Precision Production Occupations

Education

Degree: High school graduate or higher

Emails

Publications

Us Patents

Alpha Virus-Based Cytomegalovirus Vaccines

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US Patent:
7419674, Sep 2, 2008
Filed:
Jul 8, 2004
Appl. No.:
10/886773
Inventors:
Jeffrey D. Chulay - Chapel Hill NC, US
Sergey Dryga - Chapel Hill NC, US
Elizabeth A. Reap - Durham NC, US
Robert A. Olmsted - Chapel Hill NC, US
John S. Morris - Cary NC, US
Assignee:
Alpha Vax, Inc. - Research Triangle Park NC
International Classification:
A61K 39/295
A61K 39/245
C12N 7/01
C12N 15/86
US Classification:
4241991, 4241921, 4242301, 4352351, 4353201
Abstract:
The present invention provides methods and compositions comprising a population of alphavirus replicon particles comprising alphavirus replicon RNAs, wherein a first replicon RNA comprises nucleic acid encoding cytomegalovirus pp65 and IE1 protein or immunogenic fragments thereof, and a second replicon RNA comprises nucleic acid encoding cytomegalovirus gB protein or an immunogenic fragment thereof, and wherein each of the two replicon RNAs is contained within a separate alphavirus replicon particle.

Tc-83-Derived Alphavirus Vectors, Particles And Methods

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US Patent:
20050266550, Dec 1, 2005
Filed:
May 18, 2005
Appl. No.:
11/132711
Inventors:
Jon Rayner - Apex NC, US
Jonathan Smith - Cary NC, US
Bolyn Hubby - Chapel Hill NC, US
Elizabeth Reap - Durham NC, US
Assignee:
Alphavax, Inc. - Research Triangle Park NC
International Classification:
C12P021/06
A61K039/12
C12N015/00
C12N015/09
C12N015/63
C12N015/70
C12N015/74
US Classification:
435320100, 424199100, 424204100, 435069100
Abstract:
The present disclosure provides TC-83 VEE-derived replicons, alphaviral replicon particles and immunogenic compositions containing TC-83 alphaviral replicon particles which direct the expression of at least one antigen when introduced into a suitable host cell. The TC-83 VEE-derived ARPs described herein are improved in that they are subject to a lower vector-specific immune response than prior art ARPs.

Tc-83-Derived Alphavirus Vectors, Particles And Methods

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US Patent:
20110027306, Feb 3, 2011
Filed:
Jul 6, 2010
Appl. No.:
12/831017
Inventors:
Jon O. Rayner - Olathe KS, US
Jonathan F. Smith - Cary NC, US
Bolyn Hubby - Cary NC, US
Elizabeth A. Reap - Durham NC, US
Assignee:
AlphaVax, Inc. - Research Triangle Park NC
International Classification:
A61K 39/385
C12P 21/02
C07H 21/00
A61P 37/04
A61P 31/14
US Classification:
42419611, 435 693, 536 231
Abstract:
The present disclosure provides TC-83 VEE-derived replicons, alphaviral replicon particles and immunogenic compositions containing TC-83 alphaviral replicon particles which direct the expression of at least one antigen when introduced into a suitable host cell. The TC-83 VEE-derived ARPs described herein are improved in that they are subject to a lower vector-specific immune response than prior art ARPs.

Tc-83-Derived Alphavirus Vectors, Particles And Methods

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US Patent:
20160348132, Dec 1, 2016
Filed:
Aug 11, 2016
Appl. No.:
15/234949
Inventors:
- Research Triangle Park NC, US
Jonathan F. SMITH - Cary NC, US
Bolyn HUBBY - Chapel Hill NC, US
Elizabeth A. REAP - Durham NC, US
International Classification:
C12N 15/86
A61K 39/21
A61K 39/00
C12N 7/00
C07K 14/005
A61K 39/12
Abstract:
The present disclosure provides TC-83 VEE-derived replicons, alphaviral replicon particles and immunogenic compositions containing TC-83 alphaviral replicon particles which direct the expression of at least one antigen when introduced into a suitable host cell. The TC-83 VEE-derived ARPs described herein are improved in that they are subject to a lower vector-specific immune response than prior art ARPs.

Tc-83-Derived Alphavirus Vectors, Particles And Methods

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US Patent:
20150299728, Oct 22, 2015
Filed:
Jul 6, 2015
Appl. No.:
14/792247
Inventors:
- Research Triangle Park NC, US
Jonathan F. Smith - Cary NC, US
Bolyn Hubby - Chapel Hill NC, US
Elizabeth A. Reap - Durham NC, US
International Classification:
C12N 15/86
C12N 7/00
Abstract:
The present disclosure provides TC-83 VEE-derived replicons, alphaviral replicon particles and immunogenic compositions containing TC-83 alphaviral replicon particles which direct the expression of at least one antigen when introduced into a suitable host cell. The TC-83 VEE-derived ARPs described herein are improved in that they are subject to a lower vector-specific immune response than prior art ARPs.

Tc-83-Derived Alphavirus Vectors, Particles And Methods

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US Patent:
20140205629, Jul 24, 2014
Filed:
Mar 28, 2014
Appl. No.:
14/229736
Inventors:
- Research Triangle Park NC, US
Jonathan F. SMITH - Cary NC, US
Bolyn HUBBY - Chapel Hill NC, US
Elizabeth A. REAP - Durham NC, US
Assignee:
AlphaVax, Inc. - Research Triangle Park NC
International Classification:
C07K 14/005
US Classification:
42419611, 536 2372, 435325, 4352351, 435239
Abstract:
The present disclosure provides TC-83 VEE-derived replicons, alphaviral replicon particles and immunogenic compositions containing TC-83 alphaviral replicon particles which direct the expression of at least one antigen when introduced into a suitable host cell. The TC-83 VEE-derived ARPs described herein are improved in that they are subject to a lower vector-specific immune response than prior art ARPs.
Elizabeth A Reap from Durham, NC, age ~65 Get Report