US Patent:
20050008616, Jan 13, 2005
Inventors:
Eirik Nestaas - San Francisco CA, US
Erno Pungor - Millbrae CA, US
Assignee:
Schering Aktiengesellschaft - Berlin
International Classification:
A61K038/21
Abstract:
The present invention relates to recombinant human interferon-β-1b (“IFN-β-1b”) polypeptides, or fragments, analogs, derivatives, or variants thereof, having an improved specific activity. The present invention also relates to pharmaceutical compositions comprising such IFN-β-1b polypeptides, or fragments, analogs, derivatives, or variants thereof, useful for treating multiple sclerosis. The present invention further relates to methods of producing such IFN-β-1b compositions.