Edouard S Bouvier

20030042206, Mar 6, 2003

Sep 5, 2002

10/235608

Edouard Bouvier - Stow MA, US
Randy Meirowitz - Somerville MA, US
Patrick McDonald - Holliston MA, US

Waters Investments Ltd. - Milford MA

B01D061/00
B01D015/08

210/660000, 210/635000, 210/651000

A method for removing an organic solute from a solution, comprising contacting the solution with a polymer formed by copolymerizing one or more hydrophobic monomers and one or more hydrophilic monomers, whereby the solute is adsorbed onto the polymer. The solution can comprise a polar solvent such as a polar organic solvent or water or an aqueous buffer. The hydrophobic monomer can be, for example, divinylbenzene. The hydrophilic monomer can be, for example, a heterocyclic monomer, such as a vinylpyridine or N-vinylpyrrolidone.

20030094206, May 22, 2003

Nov 19, 2001

09/997491

Geoff Gerhardt - Milbury MA, US
Edouard Bouvier - Stow MA, US
Theodore Dourdeville - Marion MA, US

F16K049/00

137/828000

Methods and devices for the management of fluid flow within nanoscale analytical systems, comprising a freeze thaw valve having differing geomentries to constrict a frozen plug within the freeze thaw segment. The freeze thaw valve is directed to use in high-pressure analytical systems. The geometry of an inner diameter of a channel or tube within a freeze thaw segment is configured to cause constriction of a freeze plug when axial force is applied. The constriction is used in the flow-path of a freeze thaw valve to prevent movement of the frozen plug at high pressures to avoid valve leakage.

20030116707, Jun 26, 2003

Aug 19, 2002

10/223401

Jeff Brown - Cheshire, GB
Dominic Gostick - Cheshire, GB
Edouard Bouvier - Stow MA, US
John Gebler - Hopkinton MA, US
Peter Lee - Westborough MA, US
James Langridge - Cheshire, GB
Emmanuelle Claude - Altrincham, GB
Weibin Chen - Holliston MA, US

Micromass Limited - Manchester

H01J049/04

250/288000

A MALDI sample plate is disclosed which comprises a metallic substrate having a circular groove or moat . A hydrophobic polytetrafluoroethylene layer is applied to the substrate and a central portion of the substrate is laser etched which roughens the surface of the substrate . A thin polystyrene layer is then applied to the polytetrafluoroethylene layer and the central portion

20030178370, Sep 25, 2003

Mar 19, 2002

10/100762

Raymond Fisk - Norton MA, US
Pamela Iraneta - Brighton MA, US
Yuri Tuvim - Gloucester MA, US
Edouard Bouvier - Stow MA, US
Jonathan Belanger - Whitinsville MA, US
Martin Gilar - Franklin MA, US

Waters Investments Limited

B01D015/08

210/656000, 210/638000, 210/636000, 210/198200, 210/510100, 210/335000, 422/101000, 436/178000

A solid phase extraction (SPE) device having a reservoir with an opening; a well comprising an internally tapered wall, the wall having a wider interior diameter at an end closest to the opening than at an exit spout; a first filter placed within the well; a bed of sorbent particles placed within the well below the first filter; and a second filter having a diameter smaller than the first filter placed within the well below the bed of sorbent particles and above the exit spout is provided. A method of performing SPE using the device is also provided.

20040011729, Jan 22, 2004

Jul 9, 2003

10/615820

Edouard Bouvier - Stow MA, US
Randy Meirowitz - Somerville MA, US
Patrick McDonald - Holliston MA, US

Waters Investments Ltd. - Milford MA

B01D035/00

210/435000, 210/511000, 210/634000, 422/070000, 422/101000

A method for removing an organic solute from a solution comprises contacting the solution with a polymer formed by copolymerizing one or more hydrophobic monomers and one or more hydrophilic monomers, whereby the solute is adsorbed onto the polymer. The solution can comprise a polar solvent such as a polar organic solvent or water or an aqueous buffer. The hydrophobic monomer can be, for example, divinylbenzene. The hydrophilic monomer can be, for example, a heterocyclic monomer, such as a vinylpyridine or N-vinylpyrrolidone.

20040166589, Aug 26, 2004

Feb 24, 2004

10/785754

Raymond Fisk - Norton MA, US
Pamela Iraneta - Brighton MA, US
Yuri Tuvim - Gloucester MA, US
Edouard Bouvier - Stow MA, US
Jonathan Belanger - Whitinsville MA, US
Martin Gilar - Franklin MA, US

WATERS INVESTMENTS LIMITED

G01N001/18

436/178000

A solid phase extraction (SPE) device having a reservoir with an opening; a well comprising an internally tapered wall, the well having a wider interior diameter at an end closest to the opening than at an exit spout; a first filter within the well; a bed of sorbent particles within the well below the first filter; and a second filter having a diameter smaller than the first filter within the well below the bed of sorbent particles and above the exit spout is provided. A method of performing SPE using the device is also provided.

20050087685, Apr 28, 2005

May 24, 2002

10/478399

Edouard Bouvier - Stow MA, US
Bruce Compton - Lexington MA, US
Dominic Gostick - Marlborough MA, US
Jeffrey Brown - Mottram-in-Longdendale via Hyde, GB

H01J049/00

250288000

A novel Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry (MALDI-MS) desalting sample support plate is described. The plate comprises a sample presentation surface, wherein the sample presentation surface comprises at least one receiving surface of an absorbent layer, wherein the absorbent layer retains selected molecules on the receiving surface. Methods for making and using the sample support plate in conventional and automated MALDI-MS are also described.

20050133424, Jun 23, 2005

Aug 4, 2004

10/911389

Edouard Bouvier - Stow MA, US
Randy Meirowitz - Somerville MA, US
Patrick McDonald - Holliston MA, US

Waters Investments Ltd. - Milford MA

B01D015/08

210198200, 422070000, 422101000, 210511000

A method for removing an organic solute from a solution comprises contacting the solution with a polymer formed by copolymerizing one or more hydrophobic monomers and one or more hydrophilic monomers, whereby the solute is adsorbed onto the polymer. The solution can comprise a polar solvent such as a polar organic solvent or water or an aqueous buffer. The hydrophobic monomer can be, for example, divinylbenzene. The hydrophilic monomer can be, for example, a heterocyclic monomer, such as a vinylpyridine or N-vinylpyrrolidone.