US Patent:
20100298407, Nov 25, 2010
Inventors:
Joshua T. Mendell - Baltimore MD, US
Duonan Yu - Philadelphia PA, US
Assignee:
THE JOHNS HOPKINS UNIVERSITY - Baltimore MD
International Classification:
C07H 21/02
C12N 15/63
A61K 31/7105
C12N 5/00
C12N 5/09
C12Q 1/68
C40B 40/06
US Classification:
514 44 A, 536 231, 4353201, 435375, 435366, 435 6, 506 16
Abstract:
The invention provides compositions and methods for the treatment of a neoplasia. The methods of the invention involve expressing a microRNA usually repressed by Myc in a cell of a subject diagnosed as having a neoplasia.